N-(2-Phenoxyphenyl)methanesulfonamide CAS 51765-51-6 Purity >99.0% (HPLC)
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Chemical Name: N-(2-Phenoxyphenyl)methanesulfonamide
CAS: 51765-51-6
Chemical Name | N-(2-Phenoxyphenyl)methanesulfonamide |
Synonyms | 2'-Phenoxymethanesulfonanilide; (2-Phenoxy)Methylsulfonylaniline; Nimesulide Impurity B (EP/BP) |
CAS Number | 51765-51-6 |
CAT Number | RF-PI1160 |
Stock Status | In Stock |
Molecular Formula | C13H13NO3S |
Molecular Weight | 263.31 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | Brown or Off-White Solid Powder |
Purity / Analysis Method | >99.0% (HPLC) |
Melting Point | 122.0~124.0℃ |
Loss on Drying | ≤0.50% |
Single Impurity | ≤0.50% |
Total Impurities | <1.00% |
Test Standard | Enterprise Standard |
Usage | Pharmaceutical Intermediates |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
N-(2-Phenoxyphenyl)methanesulfonamide (CAS: 51765-51-6) is a metabolite of Nimesulide (CAS: 51803-78-2), Nimesulide Impurity B (EP/BP). Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. It is indicated for the treatment of acute pain, symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults. It mechanism of action is through targeting on various key mediators in the inflammatory process such as COX-2 mediated prostaglandins, free radicals, proteolytic enzymes and histamine.