1-Adamtanamine CAS 768-94-5 Chiyero>98.0% (GC)
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Dzina la Chemical | 1 - Adamtanamine |
Mawu ofanana ndi mawu | Amantadine;1-Aminoadamantane;1-Adamantylamine;Adamatan-1-Amine;Tricyclo[3.3.1.13,7]decane-1-amine |
Nambala ya CAS | 768-94-5 |
Nambala ya CAT | RF-PI2286 |
Stock Status | Mu Stock, Kupanga Mphamvu 20 MT/Mwezi |
Molecular Formula | C10H17N |
Kulemera kwa Maselo | 151.25 |
Kuchulukana | 1.066 g/cm3 |
Zomverera | Zosamva mpweya |
Kusungunuka (Kusungunuka mkati) | Methanol;Zosungunuka mu Organic Solvents.Zosasungunuka m'madzi |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera mpaka Kuwala Wachikasu kapena Crystal |
Kuyera / Kusanthula Njira | >98.0% (GC) |
Kuyera / Kusanthula Njira | 97.5 ~ 102.5% (Titration ndi HClO4) |
Melting Point | 207.0 ~ 209.0 ℃ |
Chinyezi (KF) | <0.50% |
Zotsalira pa Ignition | <0.50% |
Zonse Zonyansa | <2.00% |
Kusungunuka mu 1 N HCl | Zopanda Mtundu mpaka Kukomoka Chikaso, Zowoneka Kuti Zosawala Pang'ono 5% Pass |
Infrared Spectrum | Zimagwirizana ndi Kapangidwe |
Proton NMR Spectrum | Zimagwirizana ndi Kapangidwe |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Pharmaceutical Intermediates |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
1-Adamantanamine, yomwe imadziwikanso kuti Amantadine kapena 1-Aminoadamantane kapena 1-Adamantylamine (CAS: 768-94-5) imakhala ngati chothandizira mu enantioselective strecker reaction ya phosphinoyl imines.Ndiwothandizanso pakuphatikizika kwa zotumphukira za adamantane, mwachitsanzo, Amantadine Hydrochloride.1-Adamntanamine ndi membala wa gulu la adamantanes omwe amagwiritsidwa ntchito m'makampani opanga mankhwala monga antiviral ndi antiparkinsonian mankhwala.Chithandizo cha Parkinsonism ndi kuphatikiza Levodopa, anticholinergic mankhwala, ndi amantadine amapereka zotsatira zabwino kuposa kugwiritsa ntchito mankhwala aliwonse payekhapayekha.Ndiwotsutsa wofooka wa NMDA glutamate receptor, yomwe ingapangitse kutulutsidwa kwa dopamine ndikuletsa kubwezeretsanso kwa dopamine.Mankhwalawa amathanso kulimbikitsa kutulutsidwa kwa norepinephrine kuchokera kumapeto kwa mitsempha mu ubongo.Iwo akhoza kuchiza dyskinesia wa matenda Parkinson ndi kusintha dyskinesia pambuyo yaitali dopaminergic mankhwala.