(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8 ee ≥99.0% Purity ≥99.0% Bortezomib Intermediate High Purity
Perekani Othandizira a Bortezomib Okhala ndi Kuyera Kwambiri
(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8
(1R,2R,3S,5R)-(-)-2,3-Pinanediol CAS 22422-34-0
Bortezomib CAS 179324-69-7
| Dzina la Chemical | (1S,2S,3R,5S)-(+)-2,3-Pinanediol |
| Mawu ofanana ndi mawu | (1S,2S,3R,5S) -2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol |
| Nambala ya CAS | 18680-27-8 |
| Nambala ya CAT | Mtengo wa RF-CC290 |
| Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
| Molecular Formula | C10H18O2 |
| Kulemera kwa Maselo | 170.25 |
| Kusungunuka | Chloroform, Toluene |
| Mkhalidwe Wotumiza | Kutumizidwa Pansi pa Kutentha Kozungulira |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Woyera mpaka Woyera |
| Melting Point | 56.0 ~ 59.0 ℃ |
| Kutaya pa Kuyanika | ≤0.50% |
| Zotsalira pa Ignition | ≤0.50% |
| Enantiomeric Zowonjezera | ee≥99.0% |
| Kuyera / Kusanthula Njira | ≥99.0% (GC) |
| Kusinthasintha Kwachindunji [α]20/D | +8.5° mpaka +9.5° (C=6.5, Toluene) |
| Infrared Spectrum | Zimagwirizana |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | Chiral Compounds;Pharmaceutical Intermediates;Bortezomib Intermediate |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni Drum, 25kg/ng'oma, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Shanghai Ruifu Chemical Co., Ltd. ndiwopanga komanso ogulitsa (1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) okhala ndi mawonekedwe apamwamba, omwe amagwiritsidwa ntchito kwambiri muzachilengedwe. kaphatikizidwe, kaphatikizidwe wa intermediates mankhwala ndi kaphatikizidwe wabwino mankhwala.
Shanghai Ruifu Chemical Co., Ltd. imagwira ntchito yofunika kwambiri mu chemistry ya chiral, kampaniyo idadzipereka pakupanga mankhwala a chiral.Zogulitsa zathu zimayamikiridwa kwambiri ndi makasitomala.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8), ndi zothandiza Chiral reagent ntchito synthesis wa homochiral α-hydroxyketones ndi kuthetsa prolineboronate esters.Ndiwothandiziranso kalambulabwalo wa chiral allyl boronate wogwiritsidwa ntchito pokonzekera chiral β-hydroxyallylsilanes.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) ndi Pakati pa Bortezomib (CAS 179324-69-7) pochiza Multiple Myeloma.Bortezomib, wamphamvu ubiquitin proteasome (26S) inhibitor (Ki = 0.6 nM), inayambika ku US monga mankhwala a myeloma angapo.Proteasome iyi ndiyofunikira pakuwonongeka kwa proteinolytic ya mapuloteni ambiri am'ma cell ndipo imapezeka m'maselo onse.Ndikofunikira pakuwongolera njira zotupa, kuwongolera ma cell ndi mawonekedwe a jini ndipo ndi chandamale chapanthawi yake pamankhwala a khansa.
