2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4 Chiyero >99.5% (HPLC) Tipiracil Hydrochloride Intermediate Factory
Zopangira Zopanga, Ubwino Wapamwamba komanso Mtengo Wopikisana
Tipiracil Hydrochloride (CAS: 183204-72-0) Othandizira Ogwirizana
6-(Chloromethyl)uracil CAS: 18592-13-7
6-(Hydroxymethyl)uracil CAS: 22126-44-9
2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4
| Dzina la Chemical | 2-Amino-1-Pyrroline Hydrochloride |
| Mawu ofanana ndi mawu | 3,4-Dihydro-2H-Pyrrol-5-Amine Hydrochloride;2-Aminopyrrolidine HCl |
| Nambala ya CAS | 7544-75-4 |
| Nambala ya CAT | Mtengo wa RF-PI1838 |
| Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
| Molecular Formula | C4H8N2·HCl |
| Kulemera kwa Maselo | 120.58 |
| Melting Point | 171.0 mpaka 175.0 ℃ |
| Zomverera | Hygroscopic |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera | Zotsatira |
| Maonekedwe | Ufa Woyera | Ufa Woyera |
| Kuyera / Kusanthula Njira | > 99.5% (HPLC) | 99.8% |
| Kusayera Kwambiri Kumodzi | <0.50% | 0.09% |
| M'madzi (KF) | <0.50% | 0.45% |
| Proton NMR Spectrum | Zimagwirizana ndi Kapangidwe | Zimagwirizana |
| Test Standard | Enterprise Standard | |
| Kugwiritsa ntchito | Pakati pa Tipiracil Hydrochloride (CAS: 183204-72-0) | |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
2-Amino-1-Pyrroline Hydrochloride (CAS: 7544-75-4) ndi heterocyclic organic compound, yomwe ingagwiritsidwe ntchito ngati mankhwala apakati.2-Amino-1-Pyrroline Hydrochloride ndi yapakatikati ya Tipiracil Hydrochloride (CAS: 183204-72-0) pochiza Rectal Cancer.Tipiracil Hydrochloride ndi inhibitor yamphamvu komanso yampikisano ya thymidine phosphorylase (TPase) yokhala ndi mtengo wa IC50 wa 35 nM kwa TPase ya placental.Imasankha TPase kuposa ma pyrimidine-metabolizing enzymes (IC50s => 1 mM ya UPase, OPRTase, TK, ndi DPDase).TPI imalepheretsa phosphorolysis ndi kuwonongeka kwa trifluorothymidine, cytotoxic nucleoside, m'mawere a munthu ndi colon carcinoma tumor samples.Kuwongolera pakamwa kwa TPI (12.5-50 mg/kg) kumawonjezera ntchito yolimbana ndi chotupa cha trifluorothymidine mu mbewa AZ-521 ya khansa ya m'mimba ya xenograft.Mapangidwe okhala ndi TPI akhala akugwiritsidwa ntchito pochiza metastatic colorectal cancer.
