2-Chloro-5-Iodobenzoic Acid CAS 19094-56-5 Empagliflozin Intermediate Assay ≥99.0% (HPLC)

2-Chloro-5-Iodobenzoic Acid (CAS: 19094-56-5) itha kugwiritsidwa ntchito ngati mankhwala apakatikati mu synthesis ya Empagliflozin (CAS: 864070-44-0).Empagliflozin (dzina lamalonda Jardiance) ndi choletsa cha sodium glucose co-transporter-2 (SGLT-2), ndipo imapangitsa kuti shuga m'magazi atulutsidwe ndi impso ndikuchotsedwa mumkodzo.Pa Ogasiti 1, 2014, bungwe la Food and Drug Administration (FDA) lidavomereza mwalamulo mankhwala ochizira matenda amtundu wa 2, kuti apititse patsogolo ndikuwongolera shuga wamagazi mwa akulu.Empagliflozin ndi mankhwala achitatu oletsa SGLT-2 ovomerezedwa ndi FDA.Mankhwala ena awiri a SGLT-2 inhibitor, Canagliflozin ndi Dapagliflozin, a Johnson Pharmaceuticals, AstraZeneca ndi Bristol-Myers Squibb motsatana, adavomerezedwa ndi FDA mu Novembala 2013 ndi Januware 2014 motsatana.