2-Hydroxy-5-Methylpyridine CAS 1003-68-5 Purity ≥99.0% Pirfenidone Intermediate Factory
Wopanga Zinthu, Kuyera Kwambiri, Kupanga Zamalonda
Dzina la Mankhwala: 2-Hydroxy-5-Methylpyridine
CAS: 1003-68-5
Dzina la Chemical | 2-Hydroxy-5-Methylpyridine |
Mawu ofanana ndi mawu | 5-Methyl-2 (1H) -Pyridinone;2-Hydroxy-5-Picoline;6-Hydroxy-3-Picoline;5-Methyl-2-Pyridinol |
Nambala ya CAS | 1003-68-5 |
Nambala ya CAT | RF-PI549 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C6H7NO |
Kulemera kwa Maselo | 109.13 |
Melting Point | 183.0 mpaka 187.0 ℃ (lit.) |
Kusungunuka | Zosungunuka mu Methanol |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera-Woyera kupita ku Yellow Crystalline |
Chiyero | ≥99.0% |
Chinyezi (KF) | ≤0.50% |
Zotsalira pa Ignition | ≤0.50% |
Chidetso Chilichonse Chilichonse | ≤0.50% |
Zonse Zonyansa | ≤1.00% |
Zosungunulira Zotsalira | |
n-Butanol | ≤0.30% |
Ethanol | ≤0.30% |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Pakati pa Pirfenidone (CAS: 53179-13-8) |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
2-Hydroxy-5-Methylpyridine (CAS: 1003-68-5) imagwiritsidwa ntchito ngati mankhwala apakati a Pirfenidone (CAS: 53179-13-8).Pirfenidone (PFD) ndi mtundu waposachedwa wa ma ketoni a pyridine omwe ali ndi anti-fibrotic effect, amatha kuteteza ndikusintha mapangidwe a fibrosis ndi chipsera.Idalowa msika ku Shionogi, Japan mu 2008 ndipo idavomerezedwa ndi US Food and Drug Administration.Ndiwo mankhwala oyamba omwe adutsa muyeso lachipatala la gawo lachitatu (kuphatikizapo kubwereza, kusasintha, ndi kulamulira kwa placebo) zomwe zasonyeza mphamvu zake pochiza idiopathic pulmonary fibrosis (IPF);Komanso, mankhwalawa ali ndi mphamvu wachibale wabwino pochiza matenda ena fibrotic monga aimpso interstitial fibrosis ndi chiwindi fibrosis.