2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 Tolvaptan Intermediate Factory High Quality
Wopanga Zinthu, Ubwino Wapamwamba, Kupanga Zamalonda
Tolvaptan ndi Othandizira Ogwirizana:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
Dzina la Chemical | 2-Methyl-4-Nitrobenzoic Acid |
Mawu ofanana ndi mawu | 4-Nitro-o-Toluic Acid;4-Nitro-2-Methylbenzoic Acid |
Nambala ya CAS | 1975-51-5 |
Nambala ya CAT | RF-PI397 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C8H7NO4 |
Kulemera kwa Maselo | 181.15 |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Pafupifupi Ufa Wakristalo Woyera Kapena Wotuwa |
1H-NMR | Zogwirizana ndi Kapangidwe |
Kuyera / Kusanthula Njira | ≥98.0% (HPLC) |
Melting Point | 153.0 ~ 156.0 ℃ |
Chinyezi (KF) | ≤0.50% |
Zotsalira pa Ignition | ≤0.50% |
Zonse Zonyansa | ≤2.0% |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Wapakatikati wa Tolvaptan (CAS 150683-30-0) |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.
2-Methyl-4-Nitrobenzoic Acid (CAS 1975-51-5) imagwiritsidwa ntchito ngati mankhwala apakatikati mwa kaphatikizidwe ka Tolvaptan (CAS 150683-30-0).Tolvaptan ndi wosankha, wampikisano wa arginine vasopressin receptor 2 antagonist ndi IC50 ya 1.28μM pofuna kuletsa kuphatikizika kwa mapulateleti a AVP.Tolvaptan amagwiritsidwa ntchito pochiza hyponatremia (kuchepa kwa sodium m'magazi) komwe kumalumikizidwa ndi kulephera kwamtima kwamtima, matenda a cirrhosis, ndi matenda a inappropriate antidiuretic hormone (SIADH).Tolvaptan inavomerezedwa ndi US Food and Drug Administration pa May 19, 2009, ndipo imagulitsidwa ndi Otsuka Pharmaceutical Co. pansi pa dzina lamalonda la Samsca.