3-Ethynylaniline CAS 54060-30-9 Chiyero >99.0% (GC) Erlotinib Hydrochloride Intermediate

3-Ethynylaniline, yomwe imadziwikanso kuti 3-Aminophenylacetylene (CAS: 54060-30-9) imagwiritsidwa ntchito ngati mankhwala apakatikati.3-Ethynylaniline ndi yapakatikati ya Erlotinib Hydrochloride (CAS: 183319-69-9).Erlotinib Hydrochloride ndi molekyu yaing'ono yotchedwa tyrosine kinase inhibitor yomwe imagwira ntchito mosinthika pa epidermal growth receptors, hydrochloride ya erlotinib, mankhwala omwe amapangidwa ndi maselo.Bungwe la US Food and Drug Administration (FDA) lavomereza erlotinib (Tarceva) yophatikizidwa ndi gemcitabine ngati njira yoyamba yothandizira khansa yapakhungu yam'deralo komanso metastatic.Amagwiritsidwa ntchito kwambiri ngati chithandizo chamzere wachiwiri kapena wachitatu wa khansa yam'mapapo yapamwamba kapena ya metstatic non-small cell mapapo (NSCLC) komanso ngati chithandizo cha khansa ya kapamba.Amagwiritsidwa ntchito ngati tyrosine inhibitor pamankhwala a NSCLC.Erlotinib Hydrochloride, quinazoline yotengedwa ndi molekyu yaing'ono ya epidermal growth receptor (EDGFR) tyrosine kinase, inavomerezedwa mu November, 2004, pofuna kuchiza khansa ya m'mapapo yapamwamba kapena ya metastatic yosakhala yaying'ono.