3-Nitrophthalic Anhydride CAS 641-70-3 Pomalidomide Intermediate Purity>98.0% (HPLC)
Ruifu Chemical ndi amene amapanga 3-Nitrophthalic Anhydride (CAS: 641-70-3) yokhala ndi khalidwe lapamwamba, lapakati la Pomalidomide (CAS: 19171-19-8).Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, ntchito zabwino kwambiri, zochepa komanso zochulukirapo zomwe zilipo.Gulani 3-Nitrophthalic Anhydride,Please contact: alvin@ruifuchem.com
| Pomalidomide | Chithunzi cha CAS 19171-19-8 |
| 3-Nitrophthalic Anhydride | Chithunzi cha CAS 641-70-3 |
| 3-Aminopiperidine-2,6-Dione Hydrochloride | CAS 24666-56-6;2686-86-4 |
| N, N'-Carbonyldiimidazole (CDI) | CAS 530-62-1 |
| Dzina la Chemical | 3-Nitrophthalic Anhydride |
| Mawu ofanana ndi mawu | 3-Nitrophthalic Acid Anhydride;4-Nitro-2-Benzofuran-1,3-Dione;4-Nitroisobenzofuran-1,3-Dione;4-Nitro-1,3-isobenzofurandione;Pomalidomide Impurity A |
| Stock Status | Mu Stock, Commercial Production |
| Nambala ya CAS | 641-70-3 |
| Molecular Formula | C8H3NO5 |
| Kulemera kwa Maselo | 193.11 g / mol |
| Melting Point | 161.0 mpaka 165.0 ℃ |
| Zomverera | Sichinyezimira |
| Kusungunuka kwamadzi | Ikhoza Kuwola M'madzi |
| COA & MSDS | Likupezeka |
| Chiyambi | Shanghai, China |
| Mtundu | Ruifu Chemical |
| Zinthu | Miyezo Yoyendera | Zotsatira |
| Maonekedwe | Yellow Yellow to Yellow singano Crystal kapena Crystalline Ufa | Zimagwirizana |
| Melting Point | 161.0 ~ 165.0 ℃ | 163.0 ~ 165.0 ℃ |
| Kutaya pa Kuyanika | <0.50% | 0.10% |
| Kuyera / Kusanthula Njira | >98.0% (HPLC) | 98.85% |
| Infrared Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
| 1H NMR Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
| Mapeto | Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa | |
| Kugwiritsa ntchito | Pakati pa Pomalidomide (CAS: 19171-19-8) | |
Phukusi:Botolo la Fluorinated, thumba la Aluminiyamu zojambulazo, 25kg / Cardboard Drum, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Kuzindikira mpweya.Sungani chidebecho chotsekedwa mwamphamvu ndipo sungani m'nyumba yozizira, yowuma komanso yolowera mpweya wabwino kutali ndi zinthu zomwe sizingagwirizane.Khalani kutali ndi kuwala kwa dzuwa;pewani moto;pewani chinyezi.Khalani kutali ndi oxidizing agents.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
Zizindikiro Zowopsa Xi - Zokwiyitsa
Zizindikiro Zowopsa
36/37/38 - Zokwiyitsa maso, kupuma komanso khungu.
Kufotokozera Zachitetezo
S26 - Mukakhudzana ndi maso, muzimutsuka nthawi yomweyo ndi madzi ambiri ndipo funsani malangizo achipatala.
S36 - Valani zovala zoyenera zodzitetezera.
S37/39 - Valani magolovesi oyenera komanso chitetezo chamaso / kumaso
WGK Germany 3
FLUKA BRAND F MAKODI 10-21
TSCA Inde
HS kodi 2917399090
3-Nitrophthalic Anhydride (CAS: 641-70-3) imagwiritsidwa ntchito ngati pakati pa Pomalidomide (CAS: 19171-19-8).Mu February 2013, US FDA idavomereza Pomalidomide kuti azichiza angapo myeloma (MM) kwa odwala omwe akudwala matenda atalandira chithandizo china cha khansa.Pomalidomide ndi analogi ya 4-amino ya thalidomide yokhala ndi potency yowonjezereka komanso mawonekedwe a kawopsedwe.Pomalidomide ndi thalidomide zimagwiritsa ntchito mphamvu zake mwa kusintha chitetezo cha mthupi, kulepheretsa angiogenesis, kusokoneza fupa / chotupa microenvironment, ndi kulepheretsa puloteni ya cereblon.Pomalidomide imalepheretsa kufalikira kwa m'galasi m'magulu osiyanasiyana amtundu wa MM cell, IC50 ~ 10 nM, pamene thalidomide inasonyeza pafupifupi palibe cholepheretsa mpaka 100 μM.Mu mbewa MM chotupa zitsanzo, 50 mg/kg tsiku Mlingo wa pomalidomide anachititsa chizindikiro chopinga kukula chotupa pambuyo 15 masiku mankhwala ndi kubwerera wathunthu mu 3-6 milungu motsutsana thalidomide ankachitira amazilamulira pa mlingo womwewo.Pomalidomide imakonzedwa ndi condensation ya 3-Nitrophthalic Anhydride ndi 3-Aminopiperidine-2,6-Dione yotsatiridwa ndi catalytic hydrogenation ya gulu la nitro.
