4-Amino-2-Methylbenzoic Acid CAS 2486-75-1 Tolvaptan Intermediate Factory
Wopanga Zinthu, Ubwino Wapamwamba, Kupanga Zamalonda
Tolvaptan ndi Othandizira Ogwirizana:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
Dzina la Chemical | 4-Amino-2-Methylbenzoic Acid |
Mawu ofanana ndi mawu | 4-Amino-o-toluic Acid;Tolvaptan Wapakatikati N-2 |
Nambala ya CAS | 2486-75-1 |
Nambala ya CAT | RF-PI394 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C8H9NO2 |
Kulemera kwa Maselo | 151.17 |
Kusungunuka | Zosungunuka mu Methanol |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Wakristalo Woyera kapena Wachikasu |
Kuyera/Kusanthula Njira | ≥99.0% (HPLC) |
Chinyezi | ≤0.50% (KF) |
Melting Point | 161.0 ~ 168.0 ℃ |
Zotsalira pa Ignition | ≤0.50% |
Chidetso Chimodzi | ≤0.50% |
Zonse Zonyansa | ≤1.0% |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Pakati pa Tolvaptan (CAS 150683-30-0), chithandizo cha Hyponatremia |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.
4-Amino-2-Methylbenzoic Acid (CAS 2486-75-1) imagwiritsidwa ntchito ngati yapakatikati pakupanga mankhwala apakatikati ndi Active Pharmaceutical Ingredient (API) synthesis.4-Amino-2-Methylbenzoic Acid ndi yapakatikati ya Tolvaptan (CAS 150683-30-0).Tolvaptan ndi wotsutsa pakamwa wosankha vasopressin wopangidwa ndi Otsuka pochiza hyponatremia, ndipo ndi antidiuretic hormone receptor antagonist yomwe si peptide.Mankhwala akhoza kuonjezera ndende ya sodium ayoni mu plasma, ndi kuthandiza owonjezera madzi kumaliseche mu mkodzo.Mankhwala akhoza kumapangitsanso luso la impso kuthana ndi madzi, komanso kuchepetsa kwambiri kulemera ndi edema ya odwala, koma osatsagana ndi kuchuluka kwa electrolyte excretion, popanda kuwononga magazi a electrolyte.Mankhwala angagwiritsidwe ntchito pochiza hyponatremia chifukwa congestive mtima kulephera, zosiyanasiyana edematous matenda, matenda enaake ndi antidiuretic timadzi akusowa syndrome.