5-Bromo-2-Chloro-4′-Ethoxydiphenylmethane CAS 461432-23-5 Dapagliflozin Intermediate Factory
Wopanga Zinthu, Kuyera Kwambiri, Kupanga Zamalonda
Dapagliflozin (CAS: 461432-26-8) Zowonjezera Zogwirizana:
5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
| Dzina la Chemical | 5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane |
| Mawu ofanana ndi mawu | 4-Bromo-1-Chloro-2-(4-Ethoxybenzyl)benzene;4-(5-Brom-2-Chlorbenzyl)phenyl-Ethylether;Dapagliflozin Bromo Impurity |
| Nambala ya CAS | 461432-23-5 |
| Nambala ya CAT | RF-PI447 |
| Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
| Molecular Formula | Chithunzi cha C15H14BrClO |
| Kulemera kwa Maselo | 325.63 |
| Melting Point | 41.0 mpaka 43.0 ℃ |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Woyera mpaka Pael Yellow Crystalline |
| Kuyera / Kusanthula Njira | ≥99.0% (HPLC) |
| Madzi (KF) | ≤0.50% |
| Zonse Zonyansa | ≤1.0% |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | Wapakatikati wa Dapagliflozin (CAS: 461432-26-8), mtundu II shuga mellitus |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni Drum, 25kg/ng'oma, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.
4-Bromo-1-Chloro-2-(4-Ethoxybenzyl)benzene (CAS: 461432-23-5) amagwiritsidwa ntchito ngati wapakatikati pakuphatikizika kwa Dapagliflozin (CAS: 461432-26-8).Dapagliflozin ndi choletsa champhamvu, chosankha aimpso chodalira glucose cotransporter 2 (SGLT2) pochiza matenda amtundu wa 2.Dapagliflozin ndi mankhwala atsopano oletsa shuga omwe amapangidwa molumikizana ndi Bristol-Myers Squibb ndi AstraZeneca, kuvomerezedwa ndi European Medicines Agency (EMA) pa Novembara 12, 2012. Pa Januware 8, 2014, US Food and Drug Administration (FDA) idavomereza. kuti agwiritsidwe ntchito pochiza matenda amtundu wa II.
