4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Purity>98.5% (HPLC) Lenvatinib Mesylate Intermediate Factory
Ruifu Chemical Supply Lenvatinib Mesylate Intermediates Ndi Kuyera Kwambiri
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Dzina la Chemical | 4-Chloro-7-Methoxyquinoline-6-Carboxamide |
Mawu ofanana ndi mawu | 4-Chloro-7-Methoxy-6-Quinolinecarboxemide;Lenvatinib Chidetso 12;Lenvatinib Chidetso B;Lenvatinib Impurity LFS-B |
Nambala ya CAS | 417721-36-9 |
Nambala ya CAT | RF-PI1971 |
Stock Status | Mu Stock, Mphamvu Yopanga 50MT/Chaka |
Molecular Formula | C11H9ClN2O2 |
Kulemera kwa Maselo | 236.65 |
Melting Point | > 205 ℃ (Dec.) |
Kuchulukana | 1.380±0.060 g/cm3 |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera mpaka Wachikasu Wowala |
Kuyera / Kusanthula Njira | > 98.5% (HPLC) |
Kutaya pa Kuyanika | <0.50% |
Zotsalira pa Ignition | <0.50% |
Zonse Zonyansa | <1.50% |
Proton NMR Spectrum | Zimagwirizana ndi Kapangidwe |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Pakati pa Lenvatinib Mesylate (CAS: 857890-39-2) |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
4-Chloro-7-Methoxyquinoline-6-Carboxamide (CAS: 417721-36-9) amagwiritsidwa ntchito makamaka ngati wapakatikati wa Lenvatinib Mesylate (CAS: 857890-39-2).Yopangidwa ndi Eisai Inc., lenvatinib mesylate ndi vascular endothelial growth factor receptor (VEGF) inhibitor yomwe imakhala ndi zochita zotsutsana ndi VEGF subtypes 1, 2, ndi 3 ndipo idavomerezedwa ndi FDA mu 2015 kuchiza khansa ya chithokomiro yosiyana yomwe imapezeka kwanuko. mobwerezabwereza, metastatic, kapena kupita patsogolo ndipo sanayankhe chithandizo cha radioactive ayodini.Mu Meyi 2016, a FDA adavomereza mankhwalawa ngati mankhwala ophatikizika ndi everolimus pochiza matenda a renal cell carcinoma.Chifukwa chakuti VEGF (ndi fibroblast growth factor receptors, yotchedwa FGFRs) imaganiziridwa kuti imakhala ndi gawo la njira zowonetsera mtima, VEGF2R ndi FGFR zoletsa zimaganiziridwa kuti ndizo njira zomwe zimayambitsa zotsatira za lenvatinib mesylate, zomwe ndi matenda oopsa.