4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Purity>98.5% (HPLC) Lenvatinib Mesylate Intermediate Factory

Kufotokozera Kwachidule:

Dzina: 4-Chloro-7-Methoxyquinoline-6-Carboxamide

CAS: 417721-36-9

Kuyera:> 98.5% (HPLC)

Maonekedwe: Woyera-Woyera mpaka Ufa Wachikasu Wowala

Pakati pa Lenvatinib Mesylate CAS 857890-39-2

Ubwino Wapamwamba, Kupanga Zamalonda

E-Mail: alvin@ruifuchem.com


Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Chemical Properties:

Dzina la Chemical 4-Chloro-7-Methoxyquinoline-6-Carboxamide
Mawu ofanana ndi mawu 4-Chloro-7-Methoxy-6-Quinolinecarboxemide;Lenvatinib Chidetso 12;Lenvatinib Chidetso B;Lenvatinib Impurity LFS-B
Nambala ya CAS 417721-36-9
Nambala ya CAT RF-PI1971
Stock Status Mu Stock, Mphamvu Yopanga 50MT/Chaka
Molecular Formula C11H9ClN2O2
Kulemera kwa Maselo 236.65
Melting Point > 205 ℃ (Dec.)
Kuchulukana 1.380±0.060 g/cm3
Mtundu Ruifu Chemical

Zofotokozera:

Kanthu Zofotokozera
Maonekedwe Ufa Woyera mpaka Wachikasu Wowala
Kuyera / Kusanthula Njira > 98.5% (HPLC)
Kutaya pa Kuyanika <0.50%
Zotsalira pa Ignition <0.50%
Zonse Zonyansa <1.50%
Proton NMR Spectrum Zimagwirizana ndi Kapangidwe
Test Standard Enterprise Standard
Kugwiritsa ntchito Pakati pa Lenvatinib Mesylate (CAS: 857890-39-2)

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi

Ubwino:

1

FAQ:

Ntchito:

4-Chloro-7-Methoxyquinoline-6-Carboxamide (CAS: 417721-36-9) amagwiritsidwa ntchito makamaka ngati wapakatikati wa Lenvatinib Mesylate (CAS: 857890-39-2).Yopangidwa ndi Eisai Inc., lenvatinib mesylate ndi vascular endothelial growth factor receptor (VEGF) inhibitor yomwe imakhala ndi zochita zotsutsana ndi VEGF subtypes 1, 2, ndi 3 ndipo idavomerezedwa ndi FDA mu 2015 kuchiza khansa ya chithokomiro yosiyana yomwe imapezeka kwanuko. mobwerezabwereza, metastatic, kapena kupita patsogolo ndipo sanayankhe chithandizo cha radioactive ayodini.Mu Meyi 2016, a FDA adavomereza mankhwalawa ngati mankhwala ophatikizika ndi everolimus pochiza matenda a renal cell carcinoma.Chifukwa chakuti VEGF (ndi fibroblast growth factor receptors, yotchedwa FGFRs) imaganiziridwa kuti imakhala ndi gawo la njira zowonetsera mtima, VEGF2R ndi FGFR zoletsa zimaganiziridwa kuti ndizo njira zomwe zimayambitsa zotsatira za lenvatinib mesylate, zomwe ndi matenda oopsa.

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