4-Hydroxycoumarin CAS 1076-38-6 Chiyero>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga 4-Hydroxycoumarin (CAS: 1076-38-6) yokhala ndipamwamba kwambiri.Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, zochepa komanso zochulukirapo zomwe zilipo.Gulani 4-Hydroxycoumarin,Please contact: alvin@ruifuchem.com
| Dzina la Chemical | 4-Hydroxycoumarin |
| Mawu ofanana ndi mawu | 4-Hydroxy-1-Benzopyran-2-imodzi;4-Coumarinyl Mowa;4-Coumarinol;4-Hydroxy-2H-Benzo[b]pyran-2-one;4-Hydroxy-2H-Chromen-2-imodzi;4-Hydroxychromen-2-imodzi;Benzotetronic Acid |
| Stock Status | Mu Stock, Manufactured Commerce |
| Nambala ya CAS | 1076-38-6 |
| Molecular Formula | C9H6O3 |
| Kulemera kwa Maselo | 162.14 g / mol |
| Melting Point | 213.0 ~ 217.0 ℃ (lit.) |
| Kuchulukana | 1.446 |
| Kusungunuka kwamadzi | Zosasungunuka m'madzi |
| Kusungunuka | Zosungunuka mu Ethanol ndi Dimethyl Formamide |
| Kusungirako Temp. | Malo Ozizira & Owuma |
| COA & MSDS | Likupezeka |
| Gulu | Pharmaceutical Intermediates |
| Mtundu | Ruifu Chemical |
| Zinthu | Miyezo Yoyendera | Zotsatira |
| Maonekedwe | Ufa Woyera Kapena Woyera Wamakristalo | Zimagwirizana |
| Melting Point | 213.0 ~ 217.0 ℃ | 213.6 ~ 214.7 ℃ |
| Kutaya pa Kuyanika | <0.50% | 0.32% |
| Zotsalira pa Ignition | <0.20% | 0.08% |
| Zitsulo Zolemera (Pb) | ≤10ppm | <10ppm |
| Chidetso Chimodzi | <0.30% | Zimagwirizana |
| Kuyera / Kusanthula Njira | >99.0% (HPLC) | 99.64% |
| Infrared Spectrum | Zimagwirizana ndi Kapangidwe | Zimagwirizana |
| 1 H NMR Spectrum | Zimagwirizana ndi Kapangidwe | Zimagwirizana |
| Mapeto | Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa | |
Phukusi:Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani mu chidebe chotsekedwa mwamphamvu.Sungani m'nyumba yosungiramo yozizirira, youma komanso mpweya wabwino.Tetezani ku kuwala ndi chinyezi.Zosagwirizana ndi ma oxidizing amphamvu komanso maziko amphamvu.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
4 Njira yoyesera
4.1 Maonekedwe (kuyang'ana m'maso)
4.2 Kutaya pakuyanika
4.3 Kutsimikiza kwa 4-Hydroxycoumarin
4.3.1 Njira yotsimikizira
Zitsanzozo zidasungunuka m'magawo am'manja ndikutsimikiziridwa ndi chromatography yamadzimadzi yogwira ntchito kwambiri pazambiri za C18 ndi njira yokhazikika yamalo okhazikika.
4.3.2 Regent
a) Acetonitrile: chromatographic koyera (kuchokera kunja);
b) Madzi: Madzi osungunuka kapena madzi osungunuka.
4.3.3 Chida
a) High ntchito madzi chromatography;
b) UV-chosinthika wavelength spectrometer;
c) Mzere wowunikira: C18 column;
d) Akupanga oscillators.
4.3.4 Chromatographic magwiridwe antchito
a) Mobile gawo: acetonitrile: madzi: asidi phosphoric = 700:300:1 (V/V/ V);
b) Kuthamanga: 1.0ml / min;
c) Kutentha kwa gawo: kutentha kwa chipinda;
d) Kutalika kwa mawonekedwe: 254nm
e) Kukula kwachitsanzo: 20μL
4.3.5 Kukonzekera yankho la mayeso
Kuyeza chitsanzo 20mg (zolondola 0.002g), ikani mu 25ml volumetric botolo, kupasuka ndi mafoni gawo mu 4.2.4 a) kuti sikelo, gwedezani bwino mu akupanga shaker ntchito mtsogolo.
4.3.6 Kutsimikiza kwa zomwe zili
Pansi pa zikhalidwe za 4.3.4 pamwambapa, yankho loyesa lidzatsimikiziridwa pambuyo poti chida chikhazikika.
4.3.7 Kuwerengera
Njira yokhazikika yokhazikika pamalo apamwamba idagwiritsidwa ntchito kuwerengera zotsatira.
4.3.8 Kupatuka kololedwa
Kupatuka kwa miyeso iwiriyi sikuposa 0.5%, ndipo mtengo wapakati wowerengedwa umatengedwa ngati zotsatira zoyesa.
4.4 Kutsimikiza kwa malo osungunuka.
5 Malamulo Oyendera
5.1 Gulu lililonse lazinthu lidzayesedwa ndi dipatimenti yoyang'anira zabwino malinga ndi zomwe zili mulingo uwu musanachoke kufakitale.
5.2 Kutsimikiza kwa magulu
Gulu lazinthu zopangidwa ndi kuchuluka kwa chakudya (pafupifupi 200kg).
5.3 Chitsanzo
Matumba awiri (migolo) amasankhidwa mwachisawawa kuchokera pagulu lililonse lazinthu.Pambuyo pa zitsanzo ndi kusakaniza mofanana, amagawidwa mu 50g ndi njira ya magawo anayi, omwe amagawidwa m'magawo awiri, imodzi yomwe imagwiritsidwa ntchito poyesa ndipo ina imasungidwa kuti igwiritsidwe ntchito.
5.4 Chisankho
Gulu lililonse lazinthu liyenera kuyesedwa molingana ndi zofunikira zomwe zili mulingo uwu.Ngati chinthu chilichonse chikulephera kukwaniritsa zofunikira zomwe zafotokozedwa mu muyezo uwu, chidzaloledwa kuyesedwanso ndi zitsanzo ziwiri.Ngati pali chinthu chimodzi chomwe chikulephera kukwaniritsa zofunikira zomwe zafotokozedwa mu muyezo uwu, gulu lazinthu lidzaweruzidwa kuti silinayenere.
5.5 Kuwongolera
Wogwiritsa ntchito ali ndi ufulu woyesa kuvomereza mkati mwa masiku 15 atalandira katunduyo molingana ndi zomwe zili mulingo uwu.Pakakhala kutsutsa kulikonse, mbali zonse ziwiri zitha kukambirana kuti zithetse, kapena kupatsa bungwe lovomerezeka lovomerezeka lomwe lagwirizana ndi onse awiri kuti lichite zotsutsana malinga ndi zomwe zili mulingowu.
6 Zolemba ndi zolemba
Zizindikiro zotsatirazi zidzapachikidwa ku phukusi lazinthu:
a) Dzina la malonda;
b) Nambala yokhazikika;
c) Kulemera kwa Net;
d) Tsiku lopanga kapena nambala ya batch;
e) Dzina ndi adilesi ya fakitale;
f) Moyo wa alumali.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
Zizindikiro Zowopsa
R22 - Zowopsa ngati zitamezedwa
R36/37/38 - Zokwiyitsa maso, kupuma komanso khungu.
Kufotokozera Zachitetezo
S26 - Mukakhudzana ndi maso, muzimutsuka nthawi yomweyo ndi madzi ambiri ndipo funsani malangizo achipatala.
S36 - Valani zovala zoyenera zodzitetezera.
WGK Germany 3
RTECS DJ3100000
TSCA Inde
HS kodi 2932201000
Hazard Note Irritant
4-Hydroxycoumarin (CAS: 1076-38-6) ndi hydroxycoumarin yomwe ili coumarin momwe hydrogen pa malo 4 imasinthidwa ndi gulu la hydroxy.Ndi conjugate acid ya 4-hydroxycoumarin (1-).
4-Hydroxycoumarin ndi chomera chochokera ku antioxidant, choteteza ku lipid peroxidation, komanso choletsa choletsa HIV-1 Integrase.4-Hydroxycoumarins ndi gulu lofunika kwambiri la mankhwala omwe amagwira ntchito mwachilengedwe omwe amagwiritsidwa ntchito kwambiri ngati anticoagulants-Warfarin ndi Acenocoumarol.
4-Hydroxycoumarin, yochokera ku coumarin, ndi imodzi mwazinthu zosunthika kwambiri za heterocyclic scaffolds ndipo imagwiritsidwa ntchito mobwerezabwereza popanga zinthu zosiyanasiyana.4-Hydroxycoumarin ili ndi ma electrophilic ndi nucleophilic properties.4-Hydroxycoumarin zotumphukira amagwiritsidwa ntchito monga anticoagulant, antibacterial, antifungal, antiviral, antitumor, antiprotozoal, insecticidal, antimycobacterial, antimutagenic, antioxidant, anti-inflammatory agents, HIV protease inhibitors ndi tyrosine kinase inhibitors.
4-Hydroxycoumarin imakhudzidwa ndi machitidwe a annulation, chifukwa cha kuchuluka kwa acidity kwa CH chomangira pa 3-position: magawo atatu a zochita ndi isocyanides ndi dialkyl acetylene dicarboxylates amapereka annulated 4H-pyrans.
4-Hydroxycoumarin ndi mankhwala apakati komanso mankhwala ophera tizilombo.
4-Hydroxycoumarin ndi zokometsera, ndipo ma coumarins amagawidwa kwambiri muzomera.
