4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine CAS 35144-22-0 Purity ≥99.0% (HPLC) Factory

Kufotokozera Kwachidule:

4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine

CAS: 35144-22-0

Maonekedwe: Ufa Wachikasu Wamakristalo

Kuyera: ≥99.0% (HPLC)

Intermediate of API (CAS: 177036-94-1) pochiza Pulmonary Arterial Hypertension (PAH)

Lumikizanani ndi Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com 


Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Chemical Properties:

Dzina la Chemical 4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine
Chidule Mtengo wa DLMSP
Nambala ya CAS 35144-22-0
Stock Status Mu Stock, Kupanga Kukula Mpaka Matani
Molecular Formula Chithunzi cha C7H10N2O2S
Kulemera kwa Maselo 186.23
Melting Point 80.0 ~ 84.0 ℃
Kuchulukana 1.239g/cm3
Kusungunuka (Kusungunuka mkati) Methanol
COA & MSDS Likupezeka
Chitsanzo Likupezeka
Chiyambi Shanghai, China
Mtundu Ruifu Chemical

Zofotokozera:

Kanthu Zofotokozera Zofotokozera
Maonekedwe Ufa wa Yellow Crystalline Ufa wa Yellow Crystalline
Kuyera / Kusanthula Njira ≥99.0% (HPLC) 99.60%
Melting Point 80.0 ~ 84.0 ℃ 80.0 ~ 82.0 ℃
Chinyezi (KF) ≤0.50% 0.33%
Zotsalira pa Ignition ≤0.30% 0.09%
Chidetso Chimodzi ≤0.50% <0.50%
Zitsulo Zolemera ≤20ppm <20ppm
1 H NMR Spectrum Zogwirizana ndi Kapangidwe Zimagwirizana
Mapeto Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa
Kugwiritsa Ntchito Kwambiri Intermediate of API (CAS: 177036-94-1) 

4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine (CAS: 35144-22-0) Njira Yopanga

35144-22-0

Phukusi & Kusunga:

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35144-22-0 - Zowopsa ndi Chitetezo:

Zizindikiro Zowopsa Xi - Zokwiyitsa
Zizindikiro Zowopsa
36/37/38 - Zokwiyitsa maso, kupuma komanso khungu.
Kufotokozera Zachitetezo
S26 - Mukakhudzana ndi maso, muzimutsuka nthawi yomweyo ndi madzi ambiri ndipo funsani malangizo achipatala.
S36 - Valani zovala zoyenera zodzitetezera.

35144-22-0 - Kugwiritsa Ntchito:

Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga 4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine (CAS: 35144-22-0) ndi apamwamba kwambiri.Ndi pharmaceutical Intermediate itha kugwiritsidwa ntchito popanga API (CAS: 177036-94-1).(CAS: 177036-94-1) ndi wosankha endothelin-A (ETA) receptor antagonist yomwe imayambitsidwa kuti ichiritse odwala omwe ali ndi pulmonary arterial hypertension (PAH), kuti apititse patsogolo mphamvu zolimbitsa thupi komanso kuchepetsa kuwonjezereka kwachipatala.Ndi mdani wachitatu wa ET-receptor kuti agulitsidwe chifukwa chaziwonetserozi kumbuyo kwa bosentan ndi sitaxsentan.PAH ndi matenda osowa kwambiri a mitsempha yaing'ono ya m'mapapo yomwe imadziwika ndi kuwonjezeka kwa mitsempha ndi kukonzanso, zomwe zimapangitsa kuti pakhale kuwonjezeka kwapang'onopang'ono kwa pulmonary vascular resistance ndi pulmonary arterial pressure, ndipo potsirizira pake, kulephera kwa ventricular ndi kufa msanga.Zizindikiro zoyamba za PAH zimaphatikizapo kupuma pang'ono pang'onopang'ono, kutopa, kugunda kwa mtima, edema, ndi kukomoka.

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