5-Amino-1-(2-Hydroxyethyl)pyrazole CAS 73616-27-0 Purity>99.0% (HPLC) Cefoselis Intermediate
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Dzina la Chemical | 5-Amino-1-(2-Hydroxyethyl)pyrazole |
Mawu ofanana ndi mawu | 3-Aminopyrazole-2-Ethanol;3-amino-2-Pyrazoleethanol;5-Amino-1-(beta-Hydroxyethyl)pyrazole |
Nambala ya CAS | 73616-27-0 |
Nambala ya CAT | Mtengo wa RF2586 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | Chithunzi cha C5H9N3O |
Kulemera kwa Maselo | 127.15 |
Melting Point | 107.0 mpaka 109.0 ℃ |
Boiling Point | 140 ℃/0.04 mmHg |
Kuchulukana | 1.35±0.10 g/cm3 |
Zomverera | Simamva Kutentha, Kutentha |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Wachikasu Wopepuka mpaka Wofiira Wachikasu |
Kuyera / Kusanthula Njira | >99.0% (HPLC) |
Kuyera / Kusanthula Njira | > 98.0% (Nonaqueous Titration) |
Melting Point | 107.0 mpaka 109.0 ℃ |
Kutaya pa Kuyanika | <0.50% |
Zonse Zonyansa | <1.00% |
1 H NMR Spectrum | Zogwirizana ndi Kapangidwe |
Kugwiritsa ntchito | Pakati pa Cefoselis (CAS: 122841-10-5) & Cefoselis Sulfate (CAS: 122841-12-7) |
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Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
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5-Amino-1- (2-Hydroxyethyl) pyrazole (CAS: 73616-27-0) ndi intermediates Cefoselis (CAS: 122841-10-5) & Cefoselis Sulfate (CAS: 122841-12-7).Cefoselis ndi cephalosporin yatsopano ya m'badwo wachinayi ndipo idakhazikitsidwa ku Japan ngati mankhwala oletsa matenda osiyanasiyana kuphatikiza Staphylococcus aureus (makamaka MRSA yolimbana ndi methicillin) ndi Pseudornonas aeruginosa.Itha kukonzedwa m'njira zofananira za 3, zonse zimagwiritsa ntchito 2-pyrazolomethyl-3-cephem-4-carboxylic ngati chinsinsi chapakati.M'maphunziro a preclinical, Cefolesis anali ndi ma MIC50 abwinoko kuposa Ceftazidime motsutsana ndi Streptococcus pneurnoniae kapena Staphflococcus aureus (MSSA yomva methicillin kapena kusamva MRSA) ndipo adawonetsa ntchito yayikulu yolimbana ndi Citrobacter ndi Enterobacter.Cefolesis imalekerera bwino m'maphunziro azachipatala, ndikuchotsedwa makamaka kudzera mu kusefera kwa glomerular mwa anthu.