5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4 Dapagliflozin Intermediate Factory
Wopanga Zinthu, Kuyera Kwambiri, Kupanga Zamalonda
Dapagliflozin (CAS: 461432-26-8) Zowonjezera Zogwirizana:
5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
| Dzina la Chemical | 5-Bromo-2-Chlorobenzoic Acid |
| Mawu ofanana ndi mawu | 2-Chloro-5-Bromobenzoic Acid |
| Nambala ya CAS | 21739-92-4 |
| Nambala ya CAT | RF-PI439 |
| Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
| Molecular Formula | C7H4BrClO2 |
| Kulemera kwa Maselo | 235.46 |
| Melting Point | 154.0 mpaka 156.0 ℃ (lit.) |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Woyera mpaka Wachikasu Wowala |
| Kuyesa | ≥99.0% |
| Madzi (KF) | ≤0.50% |
| Zotsalira pa Ignition | ≤0.30% |
| 2-Chlorobenzoic Acid | ≤0.30% |
| 2-Chloro-3-Bromobenzoic Acid | ≤0.30% |
| Zonse Zonyansa | ≤1.0% |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | Wapakatikati wa Dapagliflozin (CAS: 461432-26-8), mtundu II shuga mellitus |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.
5-Bromo-2-Chlorobenzoic Acid (CAS: 21739-92-4) imagwiritsidwa ntchito ngati chiyambi cha Dapagliflozin (CAS: 461432-26-8), chosankha sodium-glucose cotransporter-2 inhibitor yomwe imachepetsa aimpso. Glucose reabsorption ndipo amagwiritsidwa ntchito pochiza odwala omwe ali ndi matenda amtundu wa II.Dapagliflozin ndi choletsa champhamvu komanso chosankha cha SGLT-2(SLC5A2) chokhala ndi EC50 ya 1.1 nM.Ili ndi kupenya kwabwino pama cell a Caco-2 ndipo ndi gawo laling'ono la P-glycoprotein (P-gp).Dapagliflozin idavomerezedwa ndi FDA mu 2012.
