6-Fluoro-3-Hydroxypyrazine-2-Carbonitrile CAS 356783-31-8 Purity ≥98.0% (HPLC) Favipiravir Intermediate COVID-19

6-Fluoro-3-Hydroxypyrazine-2-Carbonitrile (CAS 356783-31-8) ndi Wapakatikati wa Favipiravir (CAS 259793-96-9).Favipiravir ndi mankhwala atsopano olimbana ndi ma virus omwe akulunjika ku RNA-dependent RNA polymerase (RdRp).Favipiravir idapangidwa kumapeto kwa zaka za m'ma 1990 ndi kampani yomwe pambuyo pake idagulidwa ndi kampani yaku Japan ya Fujifilm ngati gawo losinthira kuchoka kubizinesi yazithunzi kupita kuchipatala.Pambuyo poyesedwa motsutsana ndi ma virus angapo, mankhwalawa adavomerezedwa ku Japan mu 2014 kuti agwiritsidwe ntchito mwadzidzidzi polimbana ndi miliri ya chimfine kapena kuchiza mitundu yatsopano ya chimfine.Pakuphulika kwa coronavirus yatsopano, zotsatira za kafukufuku wazachipatala wa Phase I pamankhwala omwe adasindikizidwa mu Marichi 2020 adawonetsa kuti mankhwalawa atha kukhala ndi mphamvu yofulumizitsa kuchotsedwa kwa kachilomboka kuti achepetse kupita patsogolo kwa chibayo chatsopano cha coronavirus.Favipiravir itha kugwiritsidwa ntchito pochiza odwala omwe ali ndi COVID-19 omwe akulimbikitsidwa ndi WHO.Zinayeretsedwa ndi Drug Controller General of India (DCGI) kuti agwiritse ntchito "zoletsedwa mwadzidzidzi" pakati pa odwala COVID-19.