6-Mercaptopurine 6-MP CAS 50-44-2 Mayeso 97.0 ~ 102.0% Factory USP Standard

6-Mercaptopurine (CAS: 50-44-2) imagwiritsidwa ntchito kwambiri ndi antileukemic agent ndi immunosuppressive mankhwala omwe amalepheretsa de novo purine synthesis kupyolera mu kuphatikizira kwa thiopurine methyltransferase metabolites mu DNA ndi RNA.6-Mercaptopurine ndi analogue ya purine yomwe imakhala ngati yotsutsana ndi ma purines amkati ndipo imagwiritsidwa ntchito kwambiri ngati antileukemic agent ndi immunosuppressive mankhwala.Mercaptopurine imalepheretsa purine nucleotide synthesis ndi metabolism mwa kuletsa puloteni yotchedwa Phosphoribosyl pyrophosphate amidotransferase (PRPP Amidotransferase).Mercaptopurine imalepheretsa kutembenuka kwa nucleotide ndi kaphatikizidwe ka glycoprotein.Mercaptopurine, yogulitsidwa pansi pa dzina la Purinethol, makamaka imagwiritsidwa ntchito pochiza acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, ndi ulcerative colitis.