6-O-Methylguanine CAS 20535-83-5 Nelzarabine Intermediate Factory
Perekani Ndi Kuyera Kwambiri, Kupanga Zamalonda
Dzina la Mankhwala: 6-O-Methylguanine
CAS: 20535-83-5
| Dzina la Chemical | 6-O-Methylguanine |
| Mawu ofanana ndi mawu | 2-Amino-6-Methoxypurine |
| Nambala ya CAS | 20535-83-5 |
| Nambala ya CAT | RF-PI509 |
| Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
| Molecular Formula | C6H7N5O |
| Kulemera kwa Maselo | 165.16 |
| Melting Point | >300 ℃ (kuyatsa) |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Off-White Crystalline Powder |
| Njira Yoyesera / Kusanthula | ≥98.5% (HPLC) |
| Kutaya pa Kuyanika | ≤0.50% |
| Zotsalira pa Ignition | ≤0.50% |
| Zonse Zonyansa | ≤1.5% |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | Pakati pa Nelzarabine (CAS: 121032-29-9), T-ALL & T-LBL |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.
6-O-Methylguanine (CAS: 20535-83-5) angagwiritsidwe ntchito ngati wapakatikati mu kaphatikizidwe wa Nelzarabine (CAS: 121032-29-9).Nelarabine ndi mankhwala a deoxyguanosine analogue-9-beta-D-arabinofuranosyl guanine (ara-G).Nelarabine demethylates mu gawo la adenosine deaminase (ADA) ndipo imasandulika ara-G.Nelarabine idapangidwa bwino ndi GlaxoSmithKline.Pa Okutobala 28, 2005 movomerezedwa ndi US Food and Drug Administration, idakhala mankhwala atsopano ochiza T-cell acute lymphoblastic leukemia (T-ALL) ndi T-Cells lymphoblasticlymphoma (T-LBL) yomwe imagonjetsedwa ndi osachepera. mitundu iwiri ya mankhwala a chemotherapy kapena kubwereranso pambuyo pa chithandizo choyamba.Mankhwala atsopanowa adalembedwa ku United States mu 2006.
