7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Intermediate High Purity
Manufacturer Supply Irinotecan ndi Intermediates Zogwirizana:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Dzina la Chemical | 7-Ethyl-10-Hydroxycamptothecin |
| Mawu ofanana ndi mawu | Chithunzi cha SN-38 |
| Nambala ya CAS | 86639-52-3 |
| Nambala ya CAT | RF-PI242 |
| Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
| Molecular Formula | C22H20N2O5 |
| Kulemera kwa Maselo | 392.41 |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Wamakhiristo Woyera Wachikasu Wowala |
| Chizindikiritso (IR, UV) | (1) Ultraviolet ray mayamwidwe sipekitiramu sipekitiramu ndi zofuna (2) Infrared ray mayamwidwe sipekitiramu concordant ndi reference muyezo sipekitiramu ayenera kutsatira mayesero ovomerezeka |
| Melting Point | 228.0 ~ 235.0 ℃ |
| Zogwirizana nazo | ≤1.5% |
| 10-Hydroxycamptothecin | ≤0.30% |
| 7-Cthylcamptothecin | ≤0.70% |
| Maximum Unknown Chidetso | ≤0.50% |
| Kutaya pa Kuyanika | ≤1.0% |
| Zitsulo Zolemera | ≤10ppm |
| Zotsalira pa Ignition | ≤0.10% |
| Kumveka kwa Yankho | Zomveka |
| Kuyesa | ≥98.0% (HPLC) |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | Pharmaceutical Intermediate wa Irinotecan |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Shanghai Ruifu Chemical Co., Ltd. ndiwopanga komanso ogulitsa 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) yokhala ndipamwamba kwambiri.7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) ndi metabolite yogwira ya Topoisomerase I inhibitor Irinotecan.SN-38 (NK012) imalepheretsa DNA ndi RNA synthesis ndi IC50s ya 0.077 ndi 1.3 μM, motsatana.7-Ethyl-10-Hydroxycamptothecin (SN-38), ndi metabolite yogwira ya Irinotecan, semisynthetic yochokera ku camptothecin, alkaloid yochokera ku quinoline yomwe imapezeka mu khungwa la mtengo waku China camptotheca ndi mtengo waku Asia nothapodytes.Ngakhale kuti 7-Ethyl-10-Hydroxycamptothecin ndi yamphamvu kwambiri nthawi 1,000 kuposa Irinotecan, sinasinthidwe kukhala mankhwala osokoneza bongo chifukwa sichisungunuka.Pakali pano ikuyesedwa ndi mankhwala ophatikizana ndi magulu ena omwe pamapeto pake angalole kuti ikhale yogwira mtima ngati mankhwala a antineoplastic.
