7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1 Purity >99.0% (GC) Agomelatine Intermediate
Wopanga Wotsogola ndi Wogulitsa Agomelatine Intermediates
Agomelatine CAS 138112-76-2
7-Methoxy-1-Tetralone CAS 6836-19-7
7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
Please contact: alvin@ruifuchem.com
| Dzina la Chemical | 7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester |
| Mawu ofanana ndi mawu | Ethyl 2-(7-Methoxynaphthalen-1-yl) acetate |
| Nambala ya CAS | 6836-21-1 |
| Nambala ya CAT | Mtengo wa RF2687 |
| Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
| Molecular Formula | C15H16O3 |
| Kulemera kwa Maselo | 244.29 |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Zamadzimadzi Zowonekera Zachikasu Zowala |
| Kuyera / Kusanthula Njira | >99.0% (GC) |
| Madzi (wolemba Karl Fischer) | <0.50% |
| Zogwirizana nazo | <1.00% |
| Infrared Spectrum | Zimagwirizana ndi Kapangidwe |
| Chithunzi cha NMR | Zimagwirizana ndi Kapangidwe |
| Test Standard | Enterprise Standard |
| Kugwiritsa ntchito | Pharmaceutical Intermediate of Agomelatine (CAS: 138112-76-2) |
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7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester (CAS: 6836-21-1) is a useful organic synthetic intermediate, can used as pharmaceutical intermediate of Agomelatine (CAS: 138112-76-2).Agomelatine, yomwe imapangidwa ndi kampani yaku France Servier, ndiye woyamba padziko lonse lapansi melatonin receptors MT1 ndi MT2 agonist kalasi ya antidepressants.Zimakhudzanso chithandizo cha odwala akuluakulu omwe amavutika maganizo kwambiri.Agomelatine ndi antidepressant mankhwala.Agomelatine ndi agonist wa melatonin (MT) zolandilira komanso zotumphukira za melatonin.Imamangiriza ku MT1 ndi MT2 zolandilira (Kis = 0.14 ndi 0.41 nM, motsatira) ndipo ili ndi mtengo wa EC50 wa 0.1 nM mu [35S]GTPγS yomangirira pogwiritsa ntchito ma cell a CHO owonetsa MT2 zolandilira.Imatchulidwa ngati norepinephrine-dopamine disinhibitor (NDDI) chifukwa cha kusagwirizana ndi cholandilira cha 5-HT2C.Kutsegula kwa 5-HT2C receptors ndi serotonin kumalepheretsa dopamine ndi norepinephrine kumasulidwa.
