7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3 Purity >99.0% (HPLC) Agomelatine Intermediate

Kufotokozera Kwachidule:

Dzina la Mankhwala: 7-Methoxy-1-Naphthylacetonitrile

Mawu ofanana: 7-Methoxy-1-Naphthylmethylcyanide

CAS: 138113-08-3

Kuyera: > 99.0% (HPLC)

Maonekedwe: Ufa Wachikasu Wowala

Wapakatikati wa Agomelatine (CAS: 138112-76-2)

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Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Chemical Properties:

Dzina la Chemical 7-Methoxy-1-Naphthylacetonitrile
Mawu ofanana ndi mawu 7-Methoxy-1-Naphthylmethylcyanide;7-Methoxy-1-Naphthaleneacetinitrile;1-Cyanomethyl-7-Methoxynaphthalene;2-(7-Methoxy-1-Naphthyl)acetonitrile;2-(7-Methoxynaphthalen-1-yl)acetonitrile;Chidetso cha Agomelatine 12;Agomelatine Intermediate 1
Nambala ya CAS 138113-08-3
Nambala ya CAT Mtengo wa RF2504
Stock Status Mu Stock, Mphamvu Yopanga Matani 30 pamwezi
Molecular Formula C13H11NO
Kulemera kwa Maselo 197.24
Melting Point 83.0 mpaka 86.0 ℃
Kuchulukana 1.135±0.06 g/cm3
Refractive Index n20/D 1.44
Kusungunuka Zosungunuka mu Methanol
Mtundu Ruifu Chemical

Zofotokozera:

Kanthu Zofotokozera
Maonekedwe Ufa Wachikasu Wowala
Kuyera / Kusanthula Njira >99.0% (HPLC)
Melting Point 83.0 ~ 86.0 ℃
Kutaya pa Kuyanika <0.50%
Zotsalira pa Ignition <0.20%
Chidetso Chimodzi <0.50%
Zonse Zonyansa <1.00%
Zitsulo Zolemera <20ppm
Proton NMR Spectrum Zimagwirizana ndi Kapangidwe
Test Standard Enterprise Standard
Kugwiritsa ntchito Pharmaceutical Intermediates;Agomelatine Intermediate

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi

Ubwino:

Mphamvu Zokwanira: Malo okwanira ndi akatswiri

Utumiki Waukatswiri: Ntchito imodzi yosiya kugula

Phukusi la OEM: Phukusi lamwambo ndi zolemba zilipo

Kutumiza Mwachangu: Ngati mkati mwa katundu, kuperekedwa kwamasiku atatu kumatsimikizika

Zinthu Zokhazikika: Khalani ndi katundu wokwanira

Thandizo laukadaulo: Yankho laukadaulo likupezeka

Custom Synthesis Service: Kuchokera pa magalamu mpaka ma kilos

Ubwino Wapamwamba: Anakhazikitsa dongosolo lathunthu lotsimikizira zaubwino

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Ntchito:

7-Methoxy-1-Naphthylacetonitrile (CAS: 138113-08-3) ndi wapakatikati wa Agomelatine (CAS: 138112-76-2).Agomelatine, yomwe imapangidwa ndi kampani yaku France Servier, ndiye woyamba padziko lonse lapansi melatonin receptors MT1 ndi MT2 agonist kalasi ya antidepressants.Agomelatine amagwiritsidwa ntchito pochiza odwala akuluakulu omwe ali ndi vuto lalikulu lachisokonezo.Agomelatine ndi antidepressant yatsopano yokhala ndi zochita zosankhidwa za agonist pa melatonin zolandilira komanso zochita zotsutsana ndi serotonin 5HT-2C zolandilira.Izi sizimakhudza kutengeka kwa serotonin, noradrenaline kapena dopamine.Agomelatine ingathandize kuwongolera 'body clock' (circadian rhythm) yokhala ndi phindu pa kukhumudwa ndi kugona kwa tulo Agomelatine amagwiritsidwa ntchito pochiza kuvutika maganizo kapena kuteteza kuvutika maganizo kubwereranso, ndi kupezeka kokha ndi mankhwala a dokotala.Agomelatine - Matenda a Maganizo Gulu lina la "blockbuster" la mankhwala.Agomelatine ali ndi antidepressant, anti-nkhawa, kusintha kayimbidwe ka tulo ndikuwongolera momwe mawotchi achilengedwe amagwirira ntchito, komanso zoyipa zake, kuchita zogonana popanda zovuta, komanso kusayankha kosiya.Agomelatine imakhala ndi zotsatira zabwino kwa odwala omwe ali ndi vuto la kuvutika maganizo, ndipo zotsatira zake zimakhala zochepa kwambiri.Mlingo wovomerezeka wa Agomelatine nthawi zambiri ndi 25mg tsiku lililonse mkati mwa theka la ola musanagone.

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