S-Adenosyl-L-Methionine (Ademetionine; SAMe) CAS 29908-03-0

Kufotokozera Kwachidule:

Dzina Lamankhwala: S-Adenosyl-L-Methionine

Mawu ofanana: Ademetionine;S-adenosylmethionine;SAMENE

CAS: 29908-03-0

Maonekedwe: Pafupifupi Ufa Woyera Woyera (Wokwera Kwambiri)

Lumikizanani ndi Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Ruifu Chemical ndi amene amapanga S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) yokhala ndi khalidwe lapamwamba.Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, ntchito zabwino kwambiri, zochepa komanso zochulukirapo zomwe zilipo.Gulani S-Adenosyl-L-Methionine,Please contact: alvin@ruifuchem.com

Chemical Properties:

Dzina la Chemical	S-Adenosyl-L-Methionine
Mawu ofanana ndi mawu	Ademetionine;S-adenosylmethionine;SAMe;SAM;AdoMet
Stock Status	Mu Stock, Commercial Production
Nambala ya CAS	29908-03-0
Molecular Formula	Chithunzi cha C15H22N6O5S
Kulemera kwa Maselo	398.44 g / mol
Melting Point	267.0 ~ 269.0 ℃
Zomverera	Kwambiri Hygroscopic
Kusungunuka kwamadzi	Zosungunuka mu Madzi
Kununkhira & Kukoma	Makhalidwe
COA & MSDS	Likupezeka
Chitsanzo	Likupezeka
Chiyambi	Shanghai, China
Mtundu	Ruifu Chemical

Zofotokozera:

Zinthu	Zofotokozera	Zotsatira
Maonekedwe	Ufa Wabwino Woyera Kwambiri (Wokhala ndi Hygroscopic)	Zatsimikiziridwa
Kusungunuka	Zosungunuka mu Madzi
Chizindikiritso	1. Chemical anachita	Kuchita bwino
	2. IR: Mogwirizana ndi sipekitiramu yopezedwa ndi RS	Zatsimikiziridwa
	3. Nthawi yosungira pachimake chachikulu imakwaniritsa zopempha	Zatsimikiziridwa
Mtengo wa Acid	1.5-2.5	1.9
Kumveka ndi Mtundu wa Solution	Osati Wakuda Kwambiri Kuposa RS Y1	Zatsimikiziridwa
Madzi ndi Karl Fischer	≤3.00%	2.2%
Zotsalira pa Ignition	≤0.30%	0.14%
Zitsulo Zolemera (Pb)	≤10ppm	<10ppm
Endotoxin	≤0.3EU/mg	Zatsimikiziridwa
Microbiological	Ziyenera Kukwaniritsa Zofunikira
Total Plate Count	≤1000cfu/g	55cfu/g
Yisiti & Mold	≤100cfu/g	12cfu/g
E. Coli	Palibe / 10g	Zimagwirizana
S. Aureus	Palibe / 10g	Zimagwirizana
Salmonella	Palibe / 10g	Zimagwirizana
S-Adenosyl-L-Homocysteine	≤0.50%	0.10%
Methioadenosine	≤1.00%	0.24%
Adenine	≤0.50%	0.09%
Zogwirizana nazo
Zonyansa Zina Zazikulu Kwambiri	≤0.20%	0.01%
Zina Zonse Zonyansa	≤0.50%	0.006%
(S,S) Izomera	> 62.0%	79.4%
Butanedisulfonate	46.0 ~ 49.0% (Base on Dried)	47.5%
Ademetionine	50.0 ~ 53.0% (Base on Dried)	52.1%
Zonse Zamkatimu	> 97.5% (Base on Dried)	99.6%
Mapeto	Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa
Shelf Life	Zaka 2 Zosungidwa Moyenera

Phukusi/kusungirako/Manyamulidwe:

Phukusi:Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani chidebecho chotsekedwa mwamphamvu ndipo sungani m'nyumba yozizira, yowuma komanso yolowera mpweya wabwino kutali ndi zinthu zomwe sizingagwirizane.Tetezani ku kuwala ndi chinyezi.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.

Ubwino:

Mphamvu Zokwanira: Malo okwanira ndi akatswiri

Utumiki Waukatswiri: Ntchito imodzi yosiya kugula

Phukusi la OEM: Phukusi lamwambo ndi zolemba zilipo

Kutumiza Mwachangu: Ngati mkati mwa katundu, kuperekedwa kwamasiku atatu kumatsimikizika

Zinthu Zokhazikika: Khalani ndi katundu wokwanira

Thandizo laukadaulo: Yankho laukadaulo likupezeka

Custom Synthesis Service: Kuchokera pa magalamu mpaka ma kilos

Ubwino Wapamwamba: Anakhazikitsa dongosolo lathunthu lotsimikizira zaubwino

FAQ:

Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.

Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.

Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.

UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.

Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.

MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.

Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.

Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.

Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.

Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.

Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.

29908-03-0 - Zowopsa ndi Chitetezo:

Zizindikiro Zowopsa R49 - Zingayambitse khansa pokoka mpweya
R23 - Poizoni pokoka mpweya
R34 - Imayambitsa kuyaka
Kufotokozera Zachitetezo S53 - Pewani kuwonekera - pezani malangizo apadera musanagwiritse ntchito.
S23 - Osapumira nthunzi.
S36/37/39 - Valani zovala zodzitchinjiriza zoyenera, magolovesi ndi chitetezo chamaso/nkhope.
S45 - Pakachitika ngozi kapena ngati simukumva bwino, funsani upangiri wachipatala nthawi yomweyo (onetsani chizindikirocho ngati kuli kotheka.)
HS kodi 2934999099

29908-03-0 - Kugwiritsa Ntchito:

S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) ndi cosubstrate wamba yomwe imakhudzidwa ndi kusamutsidwa kwa gulu la methyl.SAMe idapezeka koyamba ku Italy ndi GL Cantoni mu 1952, SAMe ndi molekyulu yopangidwa nthawi zonse ndi maselo onse amoyo, imatha kuteteza khansa ya chiwindi, kulimbikitsa mapangidwe a minofu ya cartilaginous ndi concrescence, ingathandize kuthana ndi kukhumudwa, matenda a Alzheimer's, matenda a chiwindi, ndi ululu wamtima. Osteoarthritis, SAMe tsopano ikuvomerezedwa padziko lonse lapansi ngati mankhwala ofunikira kuchiza matenda a chiwindi.Masiku ano, SAMe imagwiritsidwa ntchito kwambiri pazamankhwala, m'makampani azakudya azaumoyo pamsika wapakhomo komanso wapadziko lonse lapansi.SAMe imagulitsidwa ku United States ngati chakudya chowonjezera.
1. S-Adenosyl-L-Methionine ndi chakudya chabwino cha chiwindi, chomwe chingalepheretse mowa, mankhwala osokoneza bongo ndi kuwonongeka kwa maselo a chiwindi;
2. S-Adenosyl-L-Methionine ali ndi mphamvu zodzitetezera pa matenda a chiwindi achangu ndi zinthu zina zomwe zimayambitsa kuwonongeka kwa chiwindi, matenda a mtima, khansa ndi zina zotero.
3. S-Adenosyl-L-Methionine yapezeka kuti ndi yothandiza ngati mankhwala ochizira nyamakazi ndi kuvutika maganizo kwakukulu.
4. Ku United States, SAM imagulitsidwa ngati chowonjezera cha zakudya pansi pa dzina lamalonda la SAM-e (lolembedwanso SAME kapena SAMe).Kafukufuku wina wasonyeza kuti kutenga SAM nthawi zonse kungathandize kuthana ndi kuvutika maganizo, matenda a chiwindi, ndi ululu wa osteoarthritis.Mayesero angapo azachipatala awonetsa kuti ndibwino kupsinjika maganizo, matenda ena a chiwindi ndi osteoarthritis.Zizindikiro zina zonse sizinatsimikizidwe.
5. Zachipatala ntchito kusintha chiwindi ntchito.Kuphatikiza ndi L-DOPA pochiza matenda a Parkinson kumatha kusintha mphamvu ya L-dopa ndikuchepetsa zotsatira zoyipa.Ululu wa m'deralo, nkhawa kwakanthawi komanso kusowa tulo pamalo opangira jakisoni zitha kuwoneka.

29908-03-0 - Zachipatala / Zaumoyo:

S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) imakhalanso ndi zotsatira zabwino zochizira nyamakazi, minofu ya fibrous, migraine ndi matenda ena, ndipo imakhala ndi zotsatira zochepa.Kumayambiriro kwa zaka za m'ma 1970, SAMe idagwiritsidwa ntchito ngati mankhwala a nyamakazi ku Ulaya.Mu 1999, US FDA idavomereza SAMe ngati mankhwala azaumoyo ndipo yakhala imodzi mwazakudya zogulitsidwa kwambiri ku United States.

29908-03-0 - Kukonzekera:

S-Adenosyl-L-Methionine imakonzedwa makamaka ndi kaphatikizidwe ka mankhwala, nayonso mphamvu ndi kusintha kwa enzymatic.The nayonso mphamvu njira ndi kuwonjezera kalambulabwalo L-Methionine kwa sing'anga zoyambira munali C ndi N magwero, ndipo kuchuluka kwa S-Adenosylmethionine angapezeke mwa culturing tizilombo maselo.Iyi ndiye njira yayikulu yopangira mafakitale a S-Adenosylmethionine.Pakati pawo, tizilombo toyambitsa matenda timene timagwiritsa ntchito kupesa titha kupezeka poyang'ana kapena kugwirizanitsa njira zomangira, zomwe zimalembedwa m'nkhani zambiri ndi zovomerezeka kunyumba ndi kunja.Kafukufuku wina wapereka njira yokonzekera S-adenosylmethionine, pogwiritsa ntchito ma polyhydroxy organic reagents kuteteza ntchito ya enzyme, pogwiritsa ntchito kalambulabwalo wa adenosine triphosphate, L-Methionine ndi ayoni a phosphate monga gawo lapansi, shuga kapena/ndi maltose monga opereka mphamvu, kuwonjezera kapangidwe kake. a ayoni zitsulo, ndi kugwiritsa ntchito permeable kupanga kupsyinjika kulimbikitsa kupanga S-Adenosylmethionine m'maselo athunthu.Ntchito zikuchokera zitsulo ayoni kulamulira otaya kagayidwe kachakudya kusintha mphamvu kudzikonda lumikiza dzuwa, kuwonjezera organic reagents kuteteza ntchito ya mabakiteriya ndi michere, ntchito permeable kupanga mavuto kukonzekera S-Adenosylmethionine, kufupikitsa kaphatikizidwe nthawi, ndi kupanga mankhwala kudziunjikira kunja kwa selo, zomwe zingapulumutse mtengo wa kupatukana wotsatira ndi kuphweka masitepe opareshoni.

29908-03-0 - Chitetezo ndi Zotsatira zake:

Zambiri zokhudzana ndi chitetezo chanthawi yayitali cha S-Adenosyl-L-Methionine ndizochepa chifukwa otenga nawo mbali m'maphunziro ambiri adazitenga kwakanthawi kochepa.Komabe, mu kafukufuku wina wa matenda a chiwindi okhudzana ndi mowa, ophunzira adatenga S-Adenosyl-L-methionine kwa zaka 2;mu phunziro limenelo, palibe zotsatira zoyipa zomwe zinanenedwa.
Anthu omwe ali ndi matenda ochititsa munthu kusinthasintha zochitika (matenda omwe amadziwika ndi kusinthasintha kwa maganizo, kuchoka ku maganizo kupita ku mania) sayenera kutenga SAMe chifukwa cha zizindikiro zawo zowawa kupatula pansi pa kuyang'aniridwa ndi wothandizira zaumoyo chifukwa SAMe ikhoza kuwonjezereka zizindikiro za mania.
Ngakhale S-Adenosyl-L-Methionine yakhala ikugwiritsidwa ntchito pochiza cholestasis pa nthawi ya mimba, chitetezo chake pa nthawi ya mimba sichinakhazikitsidwe.
SAMe ikhoza kuchepetsa zotsatira za levodopa (L-dopa), mankhwala omwe amagwiritsidwa ntchito pochiza matenda a Parkinson.N'zothekanso kuti SAMe ikhoza kuyanjana ndi mankhwala osokoneza bongo komanso zakudya zowonjezera zakudya zomwe zimawonjezera kuchuluka kwa serotonin (mankhwala opangidwa ndi mitsempha ya mitsempha), monga antidepressants, L-tryptophan, ndi St. John's wort.
Pali nkhawa yokhudzana ndi kugwiritsidwa ntchito kwa SAMe ndi anthu omwe alibe chitetezo chamthupi (monga omwe ali ndi kachilombo ka HIV).Anthu opanda chitetezo chamthupi ali pachiwopsezo cha matenda a Pneumocystis carinii, ndipo SAMe imathandizira kukula kwa kachilomboka.
Zotsatira za SAMe ndizosazolowereka, ndipo zikachitika nthawi zambiri zimakhala zovuta zazing'ono monga nseru kapena kugaya chakudya.