Afatinib Dimaleate Intermediate CAS 314771-88-5 Purity>99.0% (HPLC) Factory

Kufotokozera Kwachidule:

Dzina Lamankhwala: (S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine

CAS: 314771-88-5

Kuyera: > 99.0% (HPLC)

Maonekedwe: Ufa Wachikasu Kupita Kuwala Wachikasu

Wapakatikati wa Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Ruifu Chemical Supply Intermediates of Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-imodzi CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineChithunzi cha CAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5

Chemical Properties:

Dzina la Chemical	(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine
Mawu ofanana ndi mawu	N-(3-Chloro-4-Fluorophenyl) -6-Nitro-7-[(3S)-oxolan-3-yl]oxyquinazolin-4-Amine;7-((S)-Tetrahydrofuran-3-yloxy)-4-(3-Chloro-4-Fluorophenyl)amino-6-Nitroquinazoline;Afatinib Impurity
Nambala ya CAS	314771-88-5
Nambala ya CAT	RF-PI2027
Stock Status	Mu Stock, Kupanga Kukula Mpaka Matani
Molecular Formula	C18H14ClFN4O4
Kulemera kwa Maselo	404.78
Kuchulukana	1.534±0.060 g/cm3
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	Ufa Wachikasu mpaka Kuwala
Kuyera / Kusanthula Njira	>99.0% (HPLC)
Kutaya pa Kuyanika	<0.50%
Chidetso cha Munthu Payekha	<0.50%
Zonse Zonyansa	<1.00%
Zitsulo Zolemera	≤20ppm
Test Standard	Enterprise Standard
Kugwiritsa ntchito	Wapakatikati wa Afatinib Dimaleate (CAS: 850140-73-7)

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi

Ubwino:

FAQ:

Ntchito:

(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine (CAS: 314771-88-5) amagwiritsidwa ntchito Kukonzekera kwa Afatinib Dimaleate (CAS: 850140-73-7).Afatinib ndi mankhwala olimbana ndi khansa, m'badwo watsopano wamankhwala omwe akulimbana ndi khansa, mankhwala oyamba padziko lonse lapansi othana ndi khansa omwe amamangiriza ku banja la ErbB, ndipo ndiwothandiza komanso amayang'ana kwambiri Amaletsa chizindikiro chomwe chimayambitsa kukula kwa maselo a khansa. , kuchepetsa kapena kuchepetsa kuchuluka kwa maselo a khansa.Afatinib ali m'gulu la mankhwala omwe amadziwika kuti tyrosine kinase inhibitors.Zimagwira ntchito poletsa ntchito ya mapuloteni awiri ogwirizana kwambiri, epidermal growth factor receptor (EGFR) ndi human epidermal growth factor receptor 2 (HER2).Amagwiritsidwa ntchito pochiza odwala omwe ali ndi khansa ya m'mapapo yopanda maselo ang'onoang'ono a metastatic.Afatinib ndi mankhwala olimbana ndi khansa, m'badwo watsopano wamankhwala omwe akulimbana ndi khansa, mankhwala oyamba padziko lonse lapansi othana ndi khansa omwe amamangiriza ku banja la ErbB, ndipo ndiwothandiza komanso amayang'ana kwambiri Amaletsa chizindikiro chomwe chimayambitsa kukula kwa maselo a khansa. , kuchepetsa kapena kuchepetsa kuchuluka kwa maselo a khansa.