Atazanavir Sulfate CAS 229975-97-7 Purity ≥99.0% API Factory Anti-HIV HIV-1 Protease Inhibitor

Atazanavir Sulfate (BMS-232632 Sulfate) (CAS: 229975-97-7) ndi mtundu wa mchere wa sulphate wa atazanavir womwe ndi wosankha kwambiri wa HIV-1 protease inhibitor, ndiye woyamba wa protease inhibitor wovomerezedwa kuti agwiritsidwe ntchito kamodzi patsiku.Atazanavir Sulfate ndi gawo laling'ono komanso loletsa CYP3A4, komanso inhibitor ndi inducer ya P-glycoprotein (P-gp).Atazanavir Sulfate ndi choletsa cha SARS-CoV 3CLpro chokhala ndi IC50 ya 3.49 μM.Atazanavir Sulfate ndi azapeptide ndi HIV-protease inhibitor yomwe imagwiritsidwa ntchito pochiza matenda a HIV ndi Edzi kuphatikiza ndi Anti-HIV Agents, idapangidwa ndikukhazikitsidwa ndi Bristol-Myers Squibb (BMS), pansi pa chilolezo chapadziko lonse lapansi kuchokera ku Novartis, zochizira matenda a HIV.Atazanavir inakhazikitsidwa ku US ngati Reyataz™ mu July 2003. Antiviral.Atazanavir yawoneka kuti ndi yamphamvu kwambiri kuposa ma protease inhibitors asanu ovomerezeka pakali pano.Atazanavir mosankha imalepheretsa kusinthika kwa ma virus a Gag ndi Gag-Pol polyproteins m'maselo omwe ali ndi kachilombo ka HIV-1 pomanga malo omwe ali ndi HIV-1 protease, motero amalepheretsa kupangika kwa ma virioni okhwima.Atazanavir sagwira ntchito motsutsana ndi HIV-2.