Bicalutamide CAS 90357-06-5 API Factory High Quality Advanced Prostate Cancer
Zopanga Zopanga Zokhala ndi Chiyero Chapamwamba ndi Ubwino Wokhazikika
Dzina: Bicalutamide
CAS: 90357-06-5
Bicalutamide pochiza Advanced Prostate Cancer
API High Quality, Commercial Production
Dzina | Bicalutamide |
Mawu ofanana ndi mawu | N--[4-Cyano-3-(trifluoromethyl)phenyl]-3--[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropionamide |
Nambala ya CAS | 90357-06-5 |
Nambala ya CAT | RF-API76 |
Stock Status | Mu Stock, Kupanga Kufikira Mazana a Kilogram |
Molecular Formula | Chithunzi cha C18H14F4N2O4S |
Kulemera kwa Maselo | 430.37 |
Kutentha Kosungirako | 2-8 ℃ |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Wa Crystalline Woyera mpaka Woyera |
Chizindikiro A | IR: Spectrum yachitsanzo imafanana ndi muyezo wanthawi zonse |
Chizindikiro B | HPLC: Nthawi yosungira pachimake chachikulu cha yankho lachitsanzo imafanana ndi yankho lokhazikika |
Chizindikiro C | Chizindikiritso cha Organic Fluoride |
Kusungunuka | Zosungunuka Mwaulere mu Acetone ndi Tetrahydrofuran, Zosungunuka Pang'ono mu Ethyl Acetate |
Melting Point | 191.0 ~ 195.0 ℃ |
Mkati mwa Madzi (wolemba KF) | ≤0.20% |
Zomwe Fluoride | 15.9% ~ 18.5% |
Kutaya pa Kuyanika | ≤0.50% |
Zotsalira pa Ignition | ≤0.10% |
Zitsulo Zolemera | ≤10ppm |
Zosungunulira Zotsalira | |
Tetrahydrofuran | ≤0.072% |
Toluene | ≤0.089% |
N-Hexane | ≤0.029% |
Acetone | ≤0.50% |
Ethyl Acetate | ≤0.50% |
Zogwirizana nazo | |
N,N'-Dimethyl Acetamide | ≤0.109% |
Bicalutamide Aminobenzonitrile | ≤0.10% |
Bicalutamide Related Compound A Isomer A | ≤0.10% |
Bicalutamide Related Compound A Isomer B | ≤0.10% |
Mankhwala "Bicalutamide". | ≤0.20% |
2-Fluoro Bicalutamide | ≤0.20% |
Deoxy Bicalutamide | ≤0.20% |
Bicalutamide sulfide | ≤0.10% |
Chidetso Chilichonse Chosadziwika | ≤0.10% |
Zonse Zonyansa | ≤0.50% |
Tinthu Kukula | 90% <10um;50% <5um |
Kuyesa | 98.0% ~ 102.0% (zouma) |
Mayeso a Microbiological | |
Total Viable Aerobic Count | ≤500CFU/g |
Yisiti ndi Nkhungu | ≤50CFU/g |
Shelf Life | Miyezi 24 |
Test Standard | Enterprise Standard;USP Standard |
Kugwiritsa ntchito | API, pochiza Advanced Prostate Cancer |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Bicalutamide (CAS: 90357-06-5) ndi wotsutsa wa androgen wosakhala wa steroidal, yemwe amapikisana ndi androgen receptor ndi androgen, amalepheretsa kutengeka kwa androgen, ndikuletsa kumangirira kwa androgens ku chiwalo chofuna.Zimagwirizanitsa ndi androgen receptor yomwe imapanga receptor complex, yomwe imalowa mu nucleus ndikuphatikizidwa ndi nucleoprotein, motero imalepheretsa kukula kwa maselo a chotupa.Atha kukhala ngati mankhwala oyamba ochizira khansa ya prostate yapamwamba.Bicalutamide idakhazikitsidwa ku United Kingdom, msika wake woyamba padziko lonse lapansi, wochizira khansa ya prostate yapamwamba kuphatikiza ndi analogi ya LHRH kapena kuthena opaleshoni.Bicalutamide yosagwiritsa ntchito steroidal, yosankha mwapang'onopang'ono, imalepheretsa zochita za dihydrotestosterone ndi testosterone pa malo omwe akukhudzidwa ndi mpikisano womangirira ku cytosolic androgen receptor.Zinanenedwa kuti zidalekerera bwino popanda zotsatira zoyipa zamtima komanso kagayidwe kachakudya chifukwa chosowa ntchito iliyonse ya steroid.Mphamvu ya bicalutamide ngati monotherapy yawonetsedwa kuchipatala.Kuyankha koyembekezeka kudanenedwanso pochiza khansa ya colorectal, m'mawere, kapamba komanso khansa ya m'mapapo yomwe si yaying'ono.