Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8 Purity ≥99.5% (HPLC) Sitagliptin Phosphate Monohydrate Yapakatikati
Perekani Sitagliptin Phosphate Monohydrate Zogwirizana:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Wapakatikati CAS 486460-21-3
Dzina la Chemical | Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid |
Mawu ofanana ndi mawu | (R) -Sitagliptin N-Boc-Acid Chidetso |
Nambala ya CAS | 486460-00-8 |
Nambala ya CAT | Chithunzi cha RF-PI1192 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C15H18F3NO4 |
Kulemera kwa Maselo | 333.31 |
Melting Point | 136.0 ~ 138.0 ℃ |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera mpaka Woyera |
Kuzindikiridwa ndi HPLC | Nthawi Yosungira Zitsanzo ndi Concordant With Reference Standard |
Kutaya pa Kuyanika | ≤0.50% |
Phulusa la Sulfate | ≤0.50% |
Zitsulo Zolemera | <20ppm |
Isomer | ≤0.50% |
Zogwirizana nazo | |
Chidebe A | ≤0.50% |
Chidetso China Chilichonse Chimodzi | ≤0.50% |
Zonse Zonyansa | ≤0.50% |
Chiyero | ≥99.5% (HPLC) |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Wapakatikati wa Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani m'mitsuko yosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi.
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid (CAS: 486460-00-8) ndizofunikira zapakatikati pokonzekera sitagliptin.Sitagliptinphosphate ndiye choletsa choyamba cha dipeptidase -IV(DPP-4) chovomerezedwa ndi FDA mu 2006. Amagwiritsidwa ntchito pochiza matenda amtundu wa II.Imakhala ndi zotsatira zodziwikiratu za hypoglycemic ikagwiritsidwa ntchito yokha kapena kuphatikiza ndi metformin ndi pioglitazone, ndipo ndiyotetezeka kutengedwa, kulekerera bwino, popanda zovuta zingapo.Mu Ogasiti 2009, mankhwalawa adavomerezedwa ndi European Union ngati mankhwala oyamba ochizira matenda amtundu wa 2.Pambuyo pa 2011, mayiko ambiri adavomereza kuphatikiza kwa sitagliptin phosphate ndi alpha glycosidase inhibitors kapena insulin.Sitagliptin phosphate ndiye choletsa choyamba cha dipeptidyl peptidase-IV chovomerezedwa ndi FDA kuti chigwiritsidwe ntchito pochiza matenda a shuga amtundu wa 2 mpaka pano, pansi pa dzina lamalonda la Januvia.