Brexpiprazole CAS 913611-97-9 Purity>99.0% (HPLC) API Factory
Ruifu Chemical Supply Brexpiprazole Intermediates
Brexpiprazole CAS 913611-97-9
7-Hydroxyquinolinone CAS 70500-72-0
4-Bromobenzo[b]thiophene CAS 5118-13-8
1-(1-Benzothiophen-4-yl)piperazine Hydrochloride CAS 913614-18-3
7-(4-Chlorobutoxy)quinolin-2(1H)-imodzi CAS 913613-82-8
4-Chlorobenzo[b]thiophene CAS 66490-33-3
Dzina la Chemical | Brexpiprazole |
Mawu ofanana ndi mawu | OPC-34712;7-(4-(4-(Benzo[b]thiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-imodzi |
Nambala ya CAS | 913611-97-9 |
Nambala ya CAT | RF-PI1982 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | Chithunzi cha C25H27N3O2S |
Kulemera kwa Maselo | 433.57 |
Kuchulukana | 1.245±0.060 g/cm3 |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera kapena Woyera wa Crystalline |
Chizindikiritso | Ndi IR |
RT | Pansi chirality ayenera kutsatira |
Chloride | Amapereka zochita za kloridi |
Madzi | 3.0% ~ 4.5% |
Melting Point | 198.0 ~ 202.0 ℃ |
Zotsalira pa Ignition | <0.20% |
Zitsulo Zolemera | ≤10ppm |
Zogwirizana nazo | |
Chidetso cha Munthu Payekha | <0.50% |
Zonse Zonyansa | <1.00% |
EE | > 99.0% |
Kuyera / Kusanthula Njira | > 99.0% (HPLC, pa dry basis) |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | API |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
Brexpiprazole (CAS: 913611-97-9) ndi wothandizira mankhwala othandiza pochiza ndi kupewa matenda amisala kuphatikizapo CNS matenda.Brexpiprazole ndi mankhwala atsopano a antipsychotic omwe amagwira ntchito ngati serotonin ® dopamine zochita modulator ndipo awonetsa mphamvu ngati chithandizo chothandizira kwa odwala omwe ali ndi vuto lalikulu lachisokonezo (MDD).Brexpiprazole imawonetsa mawonekedwe apadera a pharmacological, akuchita ngati agonist pang'ono wa serotonin 5-HT1A ndi dopamine D2 receptors komanso ngati wotsutsa kwathunthu wa 5-HT2A ndi noradrenaline α1B / 2C receptors, ndi subnanomolar yomangirira yofanana.Brexpiprazole idapangidwa ndi Otsuka ndi Lundbeck, idavomerezedwa ndi FDA mu 2015 pochiza schizophrenia komanso ngati chithandizo chothandizira kupsinjika.Brexpiprazole amadziwika kuti ndi wolowa m'malo mwa mankhwala a Otsuka antipsychotic aripiprazole (dzina la malonda Abilify) yemwe chilolezo chake chinatha mu Ogasiti 2014.