Brimonidine Tartrate CAS 70359-46-5 Assay 99.0%~101.0%
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga Brimonidine Tartrate (CAS: 70359-46-5) yokhala ndipamwamba kwambiri.Kusankha α2-adrenergic receptor agonist, mankhwala omwe amagwiritsidwa ntchito pochiza glaucoma yotseguka kapena kuthamanga kwa magazi.Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, ntchito zabwino kwambiri, zochepa komanso zochulukirapo zomwe zilipo.Gulani Brimonidine tartrate,Please contact: alvin@ruifuchem.com
| Dzina la Chemical | Brimonidine tartrate |
| Mawu ofanana ndi mawu | Brimonidine L-Tartrate;UK 14304 Tartrate;AGN190342 Tartrate;5-Bromo-N- (4,5-Dihydro-1H-Imidazol-2-yl)quinoxalin-6-Amine Tartrate;5-Bromo-N- (4,5-Dihydro-1H-Imidazol-2-yl) -6-Quinoxalinamine Tartrate;5-Bromo-N-(4,5-Dihydro-1H-Imidazol-2-yl)quinoxalin-6-Amine (2R,3R) -2,3-Dihydroxysuccinate |
| Stock Status | Mu Stock, Commercial Production |
| Nambala ya CAS | 70359-46-5 |
| Molecular Formula | C11H10BrN5·C4H6O6 |
| Kulemera kwa Maselo | 442.23 g / mol |
| Melting Point | 207.0 ~ 208.0 ℃ (Dec.) |
| Zomverera | Simamva Kutentha, Kutentha |
| COA & MSDS | Likupezeka |
| Chiyambi | Shanghai, China |
| Shelf Life | Miyezi 24 Ngati Yasungidwa Moyenera |
| Gulu | API (Active Pharmaceutical Ingredient) |
| Mtundu | Ruifu Chemical |
| Zinthu | Zofotokozera | Zotsatira |
| Maonekedwe | Zoyera kapena Zachikasu Pang'ono kapena Pang'ono Brownish Powder | Zimagwirizana |
| Chizindikiro A | Specific Optical Rotation | Zimagwirizana |
| Chizindikiro B | Infrared Absorption Spectrophotometry | Zimagwirizana |
| Kusungunuka | Amasungunuka m'madzi, osasungunuka mu ethanol ya anhydrous ndi toluene | Zimagwirizana |
| Specific Optical Rotation | +9.0° ~ +10.5° | + 9.6 ° |
| Kutaya pa Kuyanika | ≤0.50% | 0.20% |
| Phulusa la Sulfated | ≤0.20% | 0.07% |
| Zitsulo Zolemera | ≤20ppm | <20ppm |
| Zogwirizana nazo | ||
| Zowonongeka Zodziwika | ||
| N-(imidazolidin2ylidene)quinoxalin-6-amine | ≤0.10% | Zimagwirizana |
| 5-bromoqulinoxalin-6-amine | ≤0.10% | Zimagwirizana |
| Quinoxalin-6-amine | ≤0.10% | Zimagwirizana |
| 1-(5-bromoquinoxalin-6-yl) thiourea | ≤0.10% | Zimagwirizana |
| 2-(5-bromoquinoxalin-6-yl) guanidine | ≤0.10% | Zimagwirizana |
| 5-bromo-N-(1H-imidazol-2-yl)Quinoxalin-6-amine | ≤0.10% | Zimagwirizana |
| 1-(2-aminoethyl)-3-(5-bromoquinoxalin-6-yl) urea | ≤0.10% | Zimagwirizana |
| Zidetso Zosadziŵika | ≤0.10% | Zimagwirizana |
| Zonse | ≤0.20% | 0.12% |
| Kuyesa | 99.0% ~ 101.0% (pa Maziko Ouma) | 99.8% |
| Mapeto | Izi poziwunika zimagwirizana ndi BP2015 Standard | |
Phukusi:Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani chidebecho chotsekedwa mwamphamvu ndikusunga pamalo ozizira, owuma (2~8 ℃) komanso molowera mpweya wabwino kutali ndi zinthu zomwe sizingagwirizane.Pewani kukhudzana ndi kuwala kwa dzuwa, chinyezi ndi kutentha kwambiri.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
Ndemanga Zowopsa H301: Zowopsa ngati zitamezedwa.
Ndemanga Zachitetezo
P501: Taya zamkati / chidebe kumalo ovomerezeka otaya zinyalala.
P270: Osadya, kumwa kapena kusuta mukamagwiritsa ntchito mankhwalawa.
P264: Tsukani khungu bwinobwino mukachigwira.
P301 + P310 + P330: NGATI KUMEZA: Nthawi yomweyo itanani POISON CENTRE/dotolo.Muzimutsuka pakamwa.
P405: Sitolo yotsekedwa.
Malamulo Ogwirizana:
Zambiri Zamayendedwe:
Nambala ya UN (DOT-AIR) UN2811
Kalasi (DOT-AIR) 6.1
Packing Group (TCI-A) III
Nambala ya HS 2933.29.9000
Brimonidine Tartrate (CAS: 70359-46-5) ndizosankha kwambiri α2-receptor blocker, yopangidwa bwino ndi US Company Allergan, yomwe ndi mankhwala a maso.Itha kuchepetsa kuthamanga kwa intraocular (IOP).Brimonidine Tartrate ophthalmic solution yogulitsa pamsika ndi mawonekedwe a Brimonidine Tartrate, omwe ndi mankhwala abwino otsitsa a IOP a glaucoma osatsegula komanso chithandizo cha matenda oopsa a odwala, komanso pamilingo ya argon laser IOP.Brimonidine tartrate ophthalmic njira ali wapawiri limagwirira ntchito ndi kuchepetsa amadzimadzi nthabwala kupanga ndi kuonjezera pigment wosanjikiza madzi scleral outflow achire zolinga.Pambuyo pogwera m'diso, zotsatira zake zimakhala mofulumira, ndipo zimatha kufika pachimake pogwiritsa ntchito mpaka 2h, ndipo nthawi yogwira ntchito imatha kusunga 12h.Magazi amatha kungozindikira kuchuluka kwa mankhwala.Mankhwalawa ali ndi kagayidwe kake kachiwindi, ndipo ma metabolites amachotsedwa mumkodzo ndi impso.Zokhudza zonse mayamwidwe ndi kugawa sizimakhudzidwa, ndipo okalamba safuna kusintha mlingo.Brimonidine tartrate ophthalmic njira poyerekeza ndi ena α-blockers, mafuta sungunuka ndi yaing'ono, pamene si kosavuta kudutsa magazi-ubongo chotchinga ndipo sabala sedation, hypotension ndi zina zofanana clonidine chapakati chokhwima zimachitikira.Brimonidine Tartrate Ophthalmic Solution imasankha kwambiri α2-adrenergic receptors, ndipo α2/α1 chiŵerengero cha receptor affinity ndi nthawi zoposa 1000.Zotsatira za ma receptor a alpha 2 zimatha kutsitsa kuthamanga kwa intraocular.Ndipo udindo wa alpha 1 receptors ukhoza kupangitsa kuti mitsempha ya mitsempha, kutsika kwa zikope kapena kuchepetsa komanso kukulitsa kwa wophunzira.Kugwiritsa ntchito mankhwalawa kwa nthawi yayitali sikuyambitsa kukhumudwa mwachangu.Komanso, poyerekeza ndi β-blockers, Brimonidine tartrate diso madontho kwa zazing'ono mtima zotsatira, alibe mphamvu m'mapapo ntchito, choncho ndi oyenera odwala olumala β-blockers.Kuphatikiza apo, ikagwiritsidwa ntchito yokha β-blocker, sikungakwaniritse zolinga zochiritsira, ndipo mutha kuwonjezera FDA nthawi imodzi.
