Candesartan Cilexetil CAS 145040-37-5 Purity>99.0% (HPLC) API Factory

Kufotokozera Kwachidule:

Dzina la mankhwala: Candesartan Cilexetil

CAS: 145040-37-5

Kuyera: > 99.0% (HPLC)

Maonekedwe: Ufa Woyera mpaka Woyera wa Crystalline

A Selective Angiotensin II Receptor Antagonist

API High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Ruifu Chemical Supply Candesartan Cilexetil Yapakatikati Ndi Kuyera Kwambiri
Candesartan Cilexetil CAS 145040-37-5
Candesartan CAS 139481-59-7
1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83-2
Candesartan Cilexetil Wapakatikati Eethyl Ester C6 CAS 139481-41-7
Candesartan Cilexetil Wapakatikati CAS 139481-44-0
Trityl Candesartan Cilexetil CAS 170791-09-0

Chemical Properties:

Dzina la Chemical	Candesartan Cilexetil
Mawu ofanana ndi mawu	TCV-116;1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H -benzo [d] imidazole-7-Carboxylate
Nambala ya CAS	145040-37-5
Nambala ya CAT	Mtengo wa RF-PI1891
Stock Status	Mu Stock, Kupanga Kukula Mpaka Matani
Molecular Formula	Chithunzi cha C33H34N6O6
Kulemera kwa Maselo	610.66
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	Ufa Wa Crystalline Woyera mpaka Woyera
Chizindikiro cha HPLC	Nthawi yosungira pachimake chachikulu mu chromatogram yachitsanzo imafanana ndi yomwe ili mu chromatogram yopezedwa ndi muyezo.
Chizindikiro cha IR	IR infrared mayamwidwe sipekitiramu ndi ofanana ndi Candesartan Cilexetil reference standard.
Clarity ndi Colour Solution	Njira yothetsera chloroform pa 5% ndiyowoneka bwino komanso yopanda utoto
Kuyera / Kusanthula Njira	>99.0% (HPLC)
Melting Point	155.0 ~ 160.0 ℃
Kutaya pa Kuyanika	<0.30%
Zotsalira pa Ignition	<0.10%
Zitsulo Zolemera	<10ppm
Arsenic (As)	<1ppm
Kugawa Kwakukulu kwa Particle	90% <30 μm
Zowonongeka Zachilengedwe	ndi HPLC
Ethyl Candesartan	<0.15%
Desethyl Candesartan	<0.15%
N2-Ethyl Candesartan Cilexei	<0.15%
Chidetso Chilichonse Chosadziwika	<0.15%
Zonse Zonyansa	<0.60%
Kuyesedwa ndi Potentiometry	99.0 ~ 101.0% ya C33H34N6O6, yowerengedwa pa chinthu cha anhydrous
Organic Volatile Impurity
Methano	<0.30%
Ethanol	<0.50%
Diethyl Ether	<0.50%
Aceton	<0.50%
Dichloromethan	<0.06%
Dimethylformamide	<0.088%
Kuwonongeka kwa Microbiological
Total Aerobic Microbial Count	<1000cfu/g
Nkhungu & Yisiti	<100cfu/g
E.Coli	Kulibe
Salmonella	Kulibe
Test Standard	Enterprise Standard
Kugwiritsa ntchito	API;Antihypertensive wothandizira

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi

Ubwino:

FAQ:

Ntchito:

Candesartan Cilexetil (TCV-116) (CAS: 145040-37-5) ndi angiotensin II receptor antagonist ndi IC50 ya 0.26 nM, yogwiritsidwa ntchito pochiza matenda oopsa.Candesartan ndi angiotensin-receptor blocker (ARB) yomwe ingagwiritsidwe ntchito yokha kapena ndi othandizira ena pochiza matenda oopsa.Imaperekedwa pakamwa ngati prodrug candesartan cilexetil, yomwe imasinthidwa mwachangu kukhala metabolite yake yogwira, candesartan, pakuyamwa m'mimba.Candesartan imachepetsa kuthamanga kwa magazi mwa kutsutsa dongosolo la renin-angiotensin-aldosterone (RAAS);imapikisana ndi angiotensin II pomanga mtundu wa 1 angiotensin II receptor (AT1) ndipo imalepheretsa kuthamanga kwa magazi kuwonjezereka kwa angiotensin II.Mosiyana ndi angiotensin-converting enzyme inhibitors (ACE) inhibitors, ma ARB alibe zotsatira zoyipa za chifuwa chowuma.Candesartan angagwiritsidwe ntchito pochiza matenda oopsa, akutali systolic matenda oopsa, kumanzere yamitsempha yamagazi hypertrophy ndi matenda a shuga nephropathy.Itha kugwiritsidwanso ntchito ngati njira ina yochizira kulephera kwa mtima, kukanika kwa systolic, infarction ya myocardial ndi matenda amitsempha yamagazi.