Capecitabine CAS 154361-50-9 Purity 98.0%~102.0% API High Quality
Zamalonda Zogwirizana ndi Capecitabine:
5-Fluorocytosine CAS: 2022-85-7
2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine CAS: 161599-46-8
1,2,3-Tri-O-acetyl-5-deoxy-β-D-ribofuranose CAS: 62211-93-2
Capecitabine CAS: 154361-50-9
Dzina la Chemical | Capecitabine |
Nambala ya CAS | 154361-50-9 |
Nambala ya CAT | RF-API08 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C15H22FN3O6 |
Kulemera kwa Maselo | 359.35 |
Melting Point | 110.0 ~ 121.0 ℃ |
Mkhalidwe Wotumiza | Pansi pa Kutentha kwa Ambient |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Woyera |
Chizindikiritso | Zitsanzo za IR Spectrum ziyenera kugwirizana ndi kuchuluka kwazomwe zimatchulidwa |
Chizindikiritso | HPLC: Nthawi yosungitsa pachimake chachikulu cha yankho lachitsanzo iyenera kufanana ndi muyezo wanthawi zonse. |
Chiyero | 98.0% ~ 102.0% (pa maziko a anhydrous ndi zosungunulira) |
Kuzungulira kwa Optical | +96.0°~+100° |
Chinyezi (KF) | ≤0.30% |
Zotsalira pakuyatsa | ≤0.10% |
Zitsulo Zolemera | ≤20ppm |
Zonyansa Zogwirizana A | ≤0.30% |
Zoyipa Zogwirizana B | ≤0.30% |
Zonyansa Zogwirizana ndi C | ≤0.10% (2',3'-Di O-Acety-5'-deoxy-5-Fluoroytidine) |
Chidetso Chimodzi Chosazindikirika | ≤0.10% |
Zonyansa Zonse Zosadziwika | ≤0.50% |
Zonse Zonyansa | ≤1.5% |
Zosungunulira Zotsalira (GC) | |
Methanol | ≤3000ppm |
Ethanol | ≤5000ppm |
Dichloromethane | ≤600ppm |
Ethyl Acetate | ≤5000ppm |
Toluene | ≤800ppm |
Pyridine | ≤200ppm |
Hexane | ≤290ppm |
Total Aerobic Microbial Count | ≤200cfc/g |
Yisiti ndi Nkhungu Zimawerengera | ≤50cfc/g |
Test Standard | United States Pharmacopoeia (USP) |
Kugwiritsa ntchito | Metastatic Breast Cancer |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Capecitabine (CAS: 154361-50-9) ndi mtundu watsopano wa mankhwala oral fluorinated pyrimidine.Capecitabine idapangidwa ndi Roche Pharmaceuticals, ndipo dzina lake lamalonda ndi Xeloda.Capecitabine ikhoza kusintha mu vivo kukhala 5- FU, anti-metabolizim fluorine pyrimidine deoxynucleoside carbamate mankhwala omwe amalimbana ndi maselo a khansa kuti aletse kugawanika kwa maselo ndi kusokoneza RNA ndi kaphatikizidwe ka mapuloteni.Zotsatira zake zimamangiriridwa kwambiri ku mlingo wa TP enzyme mawu mu minofu ya neoplastic ndi DPD enzyme mu vivo expression.Ndiwoyeneranso ngati chithandizo china kwa odwala khansa ya m'mawere yapamwamba kapena metastatic omwe sanayankhe paclitaxel kapena anthracycline antibiotics.Monga mankhwala oletsa khansa, amagwiritsidwa ntchito kwambiri pochiza khansa ya m'mawere yapamwamba kapena ya metastatic, komanso kuchiza khansa ya m'mapapo yopanda maselo, khansa ya m'mapapo, khansa ya m'chikhodzodzo, khansa ya m'matumbo, khansa ya m'matumbo, khansa ya m'mimba, ndi zotupa zina zolimba. .