Daclatasvir Dihydrochloride Yapakatikati CAS 1007882-23-6 Chiyero >98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga Daclatasvir Dihydrochloride Intermediate (CAS: 1007882-23-6) yokhala ndipamwamba kwambiri.Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, zochepa komanso zochulukirapo zomwe zilipo.Gulani Daclatasvir Dihydrochloride Intermediates,Please contact: alvin@ruifuchem.com
Dzina la Chemical | Di-tert-Butyl (2S,2'S)-2,2'-(4,4'-Biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-Pyrrolidinecarboxylate) |
Mawu ofanana ndi mawu | Daclatasvir Wapakatikati Ⅱ;Dacaltasvir Wapakatikati 02;Daclatasvir T-Butyl Ester;Bis(2-Methyl-2-Propanyl) (2S,2'S) -2,2'-[4,4'-Biphenyldiylbis(1H-Imidazole-4,2-diyl)]di(1-Pyrrolidinecarboxylate);Di-tert-butyl 2,2′-([1,1′-Biphenyl]-4,4′-diylbis(1H-Imidazole-5,2-diyl))(2S,2'S)-bis(Pyridineidine-1- Carboxylate);(2S,2'S)-2,2'-([1,1'-Biphenyl]-4,4'-diyldi-1H-Imidazole-5,2-diyl) bis-1-Pyrrolidinecarboxylic Acid 1,1'-Bis (1,1-Dimethylethyl) Ester;Daclatasvir Chidetso 4 |
Stock Status | Mu Stock, Commercial Production |
Nambala ya CAS | 1007882-23-6 |
Molecular Formula | C40H51ClN8O6 |
Kulemera kwa Maselo | 775.35 g / mol |
Boiling Point | 890.2±65.0℃ pa 760 mmHg |
Kuchulukana | 1.220±0.06 g/cm3 |
COA & MSDS | Likupezeka |
Chiyambi | Shanghai, China |
Gulu | Pakati pa Daclatasvir Dihydrochloride (CAS: 1009119-65-6) |
Mtundu | Ruifu Chemical |
Zinthu | Zofotokozera | Zotsatira |
Maonekedwe | Ufa Wachikasu Wopepuka mpaka Wachikasu | Ufa Wachikasu Wowala |
Kutaya pa Kuyanika | <1.00% | 0.65% |
Kusayera Kwambiri Kumodzi | <1.00% | 0.45% |
Zonse Zonyansa | <2.00% | 1.24% |
Kuyera / Kusanthula Njira | >98.0% (HPLC) | 98.76% |
Infrared Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
1H NMR Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
Mapeto | Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa | |
Kugwiritsa ntchito | Pakati pa Daclatasvir Dihydrochloride (CAS: 1009119-65-6) |
Phukusi:Botolo la Fluorinated, thumba la Aluminiyamu zojambulazo, 25kg / Cardboard Drum, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Sungani chidebecho chotsekedwa mwamphamvu ndipo sungani m'nyumba yozizira, yowuma komanso yolowera mpweya wabwino kutali ndi zinthu zomwe sizingagwirizane.Tetezani ku kuwala ndi chinyezi.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
Di-tert-Butyl (2S,2'S)-2,2'-(4,4'-Biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-Pyrrolidinecarboxylate) (CAS: 1007882-23-6) ndi wapakatikati wa Daclatasvir Dihydrochloride (CAS: 1009119-65-6).
Daclatasvir (Daklinza) wapeza udindo wa "preview review", kuphatikizapo Sorafenib pofuna kuchiza odwala akuluakulu a genotype III omwe ali ndi matenda aakulu a chiwindi C. Daklinza wakhala mankhwala oyamba omwe atsimikiziridwa kuti ndi othandiza pochiza kachilombo ka HIV ka genotype III. matenda popanda kugwiritsa ntchito limodzi ndi interferon kapena ribavirin.Interferon ndi Ribavirin ndi mankhwala awiri omwe amavomerezedwa ndi FDA pochiza matenda a hepatitis C.Hepatitis C ndi matenda a virus omwe angayambitse kutupa kwa chiwindi, zomwe zimapangitsa kuti chiwindi chizigwira ntchito bwino kapena kulephera kwa chiwindi.Odwala ambiri omwe ali ndi matenda a chiwindi C alibe zizindikiro mpaka kuwonongeka kwa chiwindi kukuwonekera, zomwe zingatenge zaka zingapo.Padziko lonse lapansi, mtundu wachitatu wa matenda a chiwindi C ndi mtundu wachiwiri wofala kwambiri wa matenda a chiwindi C pambuyo pa genotype 1 hepatitis C ndipo umatengedwa kuti ndi amodzi mwa matenda osagwirizana kwambiri ndi genotype.Daklinza ndi pan-genotype NS5A replication complex inhibitor, yokhala ndi mphamvu yoletsa kugawanika kwa RNA ndi msonkhano wa ma virus, wapawiri antiviral effect.Pa maphunziro a in vitro, Daklinza yawonetsedwa kuti ili ndi antivayirasi yolimbana ndi kachilombo ka 1 ~ 6 hepatitis C.Daklinza imatsagana ndi chenjezo loti kuphatikiza kwa amiodarone, Daklinza ndi Sofosbuvir kungayambitse kugunda kwa mtima kwambiri.Daklinza ndi piritsi pakamwa ndi mlingo woyenera wa 60 mg kwa 1 nthawi/d, molumikizana ndi Sofosbuvir kwa okwana 12 milungu.
Kampani yofufuza ndi chitukuko: Bristol-Myers Squibb.
Zolemba Patent: WO 2008021927A2 (August 9, 2007).
Nthawi yotsatsa: Julayi 24, 2015 yolembedwa ku United States, dzina lamalonda Daklinza.
Ntchito osakaniza Sofosbuvir zochizira genotype 3 matenda a chiwindi C (HCV) matenda.
Njira yochitira: HCV nonstructural protein 5A (NS5A) inhibitors.Zotsatira zoyipa: mutu ndi kutopa.
Mapangidwe ndi mawonekedwe: Mapiritsi, 30 ndi 60mg.