4-Isothiocyanato-2-(Trifluoromethyl)benzonitrile CAS 143782-23-4 Enzalutamide Intermediate Purity>98.0% (GC)
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga 4-Isothiocyanato-2-(Trifluoromethyl)benzonitrile (CAS: 143782-23-4) yokhala ndi mawonekedwe apamwamba, apakati a Enzalutamide (CAS: 915087-33-1).Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, ntchito zabwino kwambiri, zochepa komanso zochulukirapo zomwe zilipo.Gulani Enzalutamide Intermediates,Please contact: alvin@ruifuchem.com
Dzina la Chemical | 4-Isothiocyanato-2-(Trifluoromethyl) benzonitrile |
Mawu ofanana ndi mawu | 4-Cyano-3-(Trifluoromethyl)phenyl Isothiocyanate;Isothiocyanic Acid 4-Cyano-3-(Trifluoromethyl)phenyl Ester;4-Isothiocyanato-2-Trifluoromethylbenzonitrile;3-Fluoro-4-Methylphenylisothiocyanate |
Stock Status | Mu Stock, Commercial Production |
Nambala ya CAS | 143782-23-4 |
Molecular Formula | Chithunzi cha C9H3F3N2S |
Kulemera kwa Maselo | 228.19 g / mol |
Melting Point | 39.0 mpaka 43.0 ℃ |
Boiling Point | 331 ℃ |
Pophulikira | 154 ℃ |
Kuchulukana | 1.31 |
Zomverera | Sichinyezimira, Simamva Kutentha |
COA & MSDS | Likupezeka |
Chitsanzo | Likupezeka |
Chiyambi | Shanghai, China |
Mtundu | Ruifu Chemical |
Zinthu | Zofotokozera | Zotsatira |
Maonekedwe | Off-White Powder | Off-White Powder |
Melting Point | 39.0 mpaka 43.0 ℃ | 41.2 ℃ |
Kutaya pa Kuyanika | <0.50% | 0.19% |
Kuyera / Kusanthula Njira | >98.0% (HPLC) | 98.8% |
Infrared Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
1H NMR Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
Mapeto | Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa | |
Kugwiritsa ntchito | Pakati pa Enzalutamide (CAS: 915087-33-1) |
Phukusi:Botolo la Fluorinated, thumba la Aluminiyamu zojambulazo, 25kg / Cardboard Drum, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Sungani chidebecho chotsekedwa mwamphamvu ndikusunga pamalo ozizira, owuma (2~8 ℃) komanso molowera mpweya wabwino kutali ndi zinthu zomwe sizingagwirizane.Tetezani ku kuwala ndi chinyezi.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
H302 + H312 + H332: Zowopsa ngati zitamezedwa, pokhudzana ndi khungu kapena ngati mupuma mpweya.
H315: Imayambitsa kuyabwa pakhungu.
H319: Imayambitsa kukwiya kwambiri m'maso.
H335: Zingayambitse kupsa mtima.
P501: Taya zamkati / chidebe kumalo ovomerezeka otaya zinyalala.
P261: Pewani kupuma fumbi/ fume/ mpweya/ nkhungu/ nthunzi/ kutsitsi.
P270: Osadya, kumwa kapena kusuta mukamagwiritsa ntchito mankhwalawa.
P271: Gwiritsani ntchito panja pokha kapena pamalo olowera mpweya wabwino.
P264: Tsukani khungu bwinobwino mukachigwira.
P280: Valani magolovesi oteteza / zovala zoteteza / zoteteza maso / zoteteza kumaso.
P337 + P313: Ngati maso akuipiraipira: Pezani upangiri wachipatala/ chithandizo.
P305 + P351 + P338: NGATI M’MASO: Sambani mosamala ndi madzi kwa mphindi zingapo.Chotsani magalasi olumikizirana, ngati alipo komanso osavuta kuchita.Pitirizani kutsuka.
P332 + P313: Ngati kuyabwa pakhungu: Pezani malangizo achipatala.
P362: Chotsani zovala zomwe zili ndi kachilombo ndikusamba musanagwiritsenso ntchito.
P301 + P312 + P330: NGAMAKUMWA: Imbani POISON CENTER/dokotala ngati simukumva bwino.Muzimutsuka pakamwa.
P302 + P352 + P312: NGATI PAKHUMBA: Sambani ndi madzi ambiri.Imbani POISON CENTRE/dokotala ngati simukumva bwino.
P304 + P340 + P312: NGATI WOPHUNZITSIDWA: Chotsani munthu kumpweya watsopano ndikukhala womasuka kupuma.Itanani POISON CENTRE/dotolo ngati simukumva bwino.
P403 + P233: Sungani pamalo abwino mpweya wabwino.Sungani chidebe chotsekedwa mwamphamvu.
P405: Sitolo yotsekedwa.
4-Isothiocyanato-2-(Trifluoromethyl)benzonitrile (CAS: 143782-23-4) imagwiritsidwa ntchito ngati pakati pa Enzalutamide (CAS: 915087-33-1).Enzalutamide (XTANDI) ndi oral androgen receptor antagonist, omwe amavomerezedwa ndi kafukufuku waposachedwa wachipatala ndi US FDA (Food and Drug Administration), kuti apange chitukuko cha post-chemotherapy metastatic castration tolerance of Prostate cancer Treatment (ie odwala khansa ya prostate. pambuyo chemotherapy, khansa kapena maselo a khansa akukulabe mwa odwala oterowo), amatha kuwonjezera moyo wa odwala.Mu Ogasiti 2012, US FDA idavomereza enzalutamide kuti azichiza khansa ya prostate (mCRPC) kwa odwala omwe adalandirapo chithandizo m'mbuyomu.Docetaxel.