CAS 177036-94-1 Purity>99.0% (HPLC) API Factory High Purity

Kufotokozera Kwachidule:

CAS: 177036-94-1

Kuyera: > 99.0% (HPLC)

Maonekedwe: Ufa Woyera Kapena Woyera

Chithandizo cha Pulmonary Arterial Hypertension (PAH)

API High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Zogulitsa Zamalonda (CAS: 177036-94-1) Othandizira Ogwirizana:
CAS: 177036-94-1
Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate CAS: 178306-47-3
2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid CAS: 178306-51-9
(S) -2-Hydroxy-3-Methoxy-3,3-Diphenylpropionic Acid CAS: 178306-52-0
L-Proline Methyl Ester Hydrochlorid CAS: 2133-40-6
4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine CAS: 35144-22-0

Chemical Properties:

Dzina la Chemical	(S) -2- [(4,6-Dimethylpyrimidin-2-yl)oxy]-3-Methoxy-3,3-Diphenylpropionic Acid
Mawu ofanana ndi mawu	(+-)-(2S) -2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-Methoxy-3,3-Diphenylpropanoic Acid
Nambala ya CAS	177036-94-1
Stock Status	Mu Stock, Kupanga Kukula Mpaka Matani
Molecular Formula	Chithunzi cha C22H22N2O4
Kulemera kwa Maselo	378.43
Kuzungulira Kwachindunji [α]D20	+170.0° mpaka +176.0° (C=0.5, MeOH)
Melting Point	172.0 ~ 178.0 ℃ (Dec.)
Kusungunuka	Zosungunuka kwambiri mu Methanol;Zosungunuka mu Ethanol, acetone;Zosasungunuka m'madzi
Mtundu	Ruifu Chemical

Zofotokozera:

Kanthu	Zofotokozera
Maonekedwe	Ufa Woyera kapena Woyera
Chizindikiritso	HPLC;NMR;Chithunzi cha LC-MS
Zogwirizana nazo
Chidetso cha Munthu Payekha	≤0.50%
Zonse Zonyansa	<1.00%
Kutaya pa Kuyanika	≤0.50%
Zotsalira pa Ignition	≤0.20%
Zitsulo Zolemera	≤20ppm
Kuyera / Kusanthula Njira	>99.0% (HPLC)
Test Standard	Enterprise Standard
Kugwiritsa ntchito	Pharmaceutical Intermediates

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi

Ubwino:

FAQ:

Ntchito:

(CAS: 177036-94-1) APIndi wosankha endothelin-A (ETA) receptor antagonist yomwe imayambitsidwa kuti ichiritse odwala omwe ali ndi pulmonary arterial hypertension (PAH), kuti apititse patsogolo mphamvu zolimbitsa thupi komanso kuchepetsa kuwonjezereka kwachipatala.PAH ndi matenda osowa kwambiri a mitsempha yaing'ono ya m'mapapo yomwe imadziwika ndi kuwonjezeka kwa mitsempha ndi kukonzanso, zomwe zimapangitsa kuti pakhale kuwonjezeka kwapang'onopang'ono kwa pulmonary vascular resistance ndi pulmonary arterial pressure, ndipo potsirizira pake, kulephera kwa ventricular ndi kufa msanga.Zizindikiro zoyamba za PAH zimaphatikizapo kupuma pang'ono pang'onopang'ono, kutopa, kugunda kwa mtima, edema, ndi kukomoka.Endothelin-1 (ET-1), vasoconstrictor yamphamvu ndi mitogen yosalala ya minofu, ndiyomwe imathandizira kuti matendawa apitirire, ndipo zotsatira zake zimayanjanitsidwa ndi kuyambitsa kwa ETA ndi ETB receptors.Mu June 2007, a FDA adapereka chilolezo (CAS: 177036-94-1) API ya chithandizo cha PAH kamodzi patsiku.