Gefitinib Intermediate CAS 199327-61-2 Purity>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga 7-Methoxy-6-(3-Morpholin-4-ylpropoxy)quinazolin-4(3H)-One (CAS: 199327-61-2) yokhala ndi mawonekedwe apamwamba, apakati. wa Gefitinib (CAS: 184475-35-2).Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, ntchito zabwino kwambiri, zochepa komanso zochulukirapo zomwe zilipo.Gulani Gefitinib Intermediates,Please contact: alvin@ruifuchem.com
| Dzina la Chemical | 7-Methoxy-6-(3-Morpholin-4-ylpropoxy)quinazolin-4(3H)-Chimodzi |
| Mawu ofanana ndi mawu | 7-Methoxy-6-(3-Morpholinopropoxy)quinazolin-4(3H)-Mmodzi;7-Methoxy-6-[3- (4-Morpholinyl) propoxy] -4 (3H) -Quinazolinone;7-Methoxy-6-(3-Morpholinopropoxy)quinazolin-4-One |
| chidetso | Gefitinib chonyansa 5;Gefitinib EP Impurity A |
| Stock Status | Mu Stock, Commercial Production |
| Nambala ya CAS | 199327-61-2 |
| Molecular Formula | C16H21N3O4 |
| Kulemera kwa Maselo | 319.36 g / mol |
| Melting Point | 242.0 ~ 247.0 ℃ |
| Kuchulukana | 1.32±0.10 g/cm3 |
| COA & MSDS | Likupezeka |
| Chiyambi | Shanghai, China |
| Mtundu | Ruifu Chemical |
| Zinthu | Miyezo Yoyendera | Zotsatira |
| Maonekedwe | Ufa Woyera mpaka Woyera | Zimagwirizana |
| Melting Point | 242.0 ~ 247.0 ℃ | 243.6 ~ 244.5 ℃ |
| Kutaya pa Kuyanika | <0.50% | 0.15% |
| Zotsalira pa Ignition | <0.20% | 0.11% |
| Chidetso Chimodzi | <0.50% | <0.30% |
| Zonse Zonyansa | <1.00% | 0.30% |
| Kuyera / Kusanthula Njira | >99.0% (HPLC) | 99.7% |
| 1H NMR Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
| Mapeto | Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa | |
| Kugwiritsa ntchito | Pakati pa Gefitinib (CAS: 184475-35-2) | |
Phukusi:Botolo la Fluorinated, thumba la Aluminiyamu zojambulazo, 25kg / Cardboard Drum, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Sungani chidebecho chotsekedwa mwamphamvu ndikusunga pamalo ozizira, owuma (2~8 ℃) komanso molowera mpweya wabwino kutali ndi zinthu zomwe sizingagwirizane.Tetezani ku kuwala ndi chinyezi.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
7-Methoxy-6- (3-Morpholin-4-ylpropoxy)quinazolin-4 (3H)-Imodzi (CAS: 199327-61-2) ndi yapakatikati / yonyansa ya Gefitinib (CAS: 184475-35-2).Gefitinib ndi mankhwala ochiritsira omwe amatsutsana ndi zotupa omwe amapangidwa ndi AstraZeneca, UK.Gefitinib ndiye mankhwala oyamba omwe amayang'aniridwa ndi maselo ochizira khansa ya m'mapapo yopanda maselo yaying'ono.Zimagwira ntchito poletsa njira yosinthira ma siginali ya epidermal growth factor receptor tyrosine kinase (EGFR-TK).Mu Ogasiti 2002, Gefitinib idagulitsidwa koyamba ku Japan ngati chithandizo choyambirira cha khansa ya m'mapapo yopanda maselo ang'onoang'ono pansi pa dzina lamalonda la Iressa.Mu Meyi 2003, bungwe la US Food and Drug Administration lidavomereza Gefitinib ngati njira yachitatu yothandizira odwala omwe ali ndi khansa ya m'mapapo yopanda maselo ang'onoang'ono omwe sanagwiritse ntchito mankhwala oletsa khansa opangidwa ndi platinamu ndi docetaxel chemotherapy.Pakalipano, Gefitinib yavomerezedwa ndi Australia, Japan, Argentina, Singapore ndi South Korea pofuna kuchiza khansa yapakhungu yomwe si yaing'ono.Pa February 28, 2005, bungwe la China Food and Drug Administration lidavomereza Gefitinib kuti azichiza khansa ya m'mapapo yomwe inali yotsogola kwambiri kapena ya metastatic non-small cell cell (NSCLC) yomwe idalandirapo kale mankhwala a chemotherapy.Sichikuvomerezedwa kuti chigwiritsidwe ntchito ngati chithandizo choyambirira cha NSCLC yapamwamba.Pa Julayi 1, 2009, European Medicines Agency idavomereza mwalamulo Gefitinib kuti azichiza mzere woyamba, mzere wachiwiri komanso wachitatu wa khansa ya m'mapapo yomwe si yaing'ono kwambiri ya m'mapapo yomwe ili ndi EGFR mwa akulu.
