3-Chloro-4-(3-Fluorobenzyloxy)aniline CAS 202197-26-0 Lapatinib Intermediate Purity>98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga 3-Chloro-4-(3-Fluorobenzyloxy)aniline (CAS: 202197-26-0) yokhala ndi mtundu wapamwamba kwambiri.Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, ntchito zabwino kwambiri, zochepa komanso zochulukirapo zomwe zilipo.Gulani Lapatinib Intermediates,Please contact: alvin@ruifuchem.com
Dzina la Chemical | 3-Chloro-4-(3-Fluorobenzyloxy)aniline |
Mawu ofanana ndi mawu | 3-Chloro-4-[(3-Fluorophenyl)methoxy]aniline;4-(3-Fluorobenzyloxy) -3-Chlorobenzenamine;Lapatinib Intermediate B |
Stock Status | Mu Stock, Commercial Production |
Nambala ya CAS | 202197-26-0 |
Molecular Formula | Chithunzi cha C13H11ClFNO |
Kulemera kwa Maselo | 251.69 g / mol |
Melting Point | 78.0 mpaka 82.0 ℃ |
Kuchulukana | 1.306±0.06 g/cm3 |
COA & MSDS | Likupezeka |
Chitsanzo | Likupezeka |
Chiyambi | Shanghai, China |
Mtundu | Ruifu Chemical |
Zinthu | Miyezo Yoyendera | Zotsatira |
Maonekedwe | Brown mpaka Black Powder | Zimagwirizana |
Melting Point | 78.0 mpaka 82.0 ℃ | 80.7 ℃ |
Kutaya pa Kuyanika | <1.00% | Zimagwirizana |
Zotsalira pa Ignition | <0.50% | Zimagwirizana |
Zoyipa Zogwirizana ndi HPLC | <2.00% | 0.64% |
Kuyera / Kusanthula Njira | >98.0% (HPLC) | 99.36% |
1H NMR Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
Mapeto | Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa | |
Kugwiritsa ntchito | Pakati pa Lapatinib / Lapatinib Ditosylate Monohydrate |
Phukusi:Botolo la Fluorinated, thumba la Aluminiyamu zojambulazo, 25kg / Cardboard Drum, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Sungani chidebecho chotsekedwa mwamphamvu ndipo sungani m'nyumba yozizira, yowuma komanso yolowera mpweya wabwino kutali ndi zinthu zomwe sizingagwirizane.Tetezani ku kuwala ndi chinyezi.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
Ma ID a UN 3077
HS kodi 2921420090
Kalasi ya ngozi 9
Packing Gulu III
3-Chloro-4-(3-Fluorobenzyloxy)aniline (CAS: 202197-26-0) ndi yapakatikati mu kaphatikizidwe ka Lapatinib / Lapatinib Ditosylate Monohydrate.
Lapatinib ndi mankhwala omwe amalimbana ndi khansa ya m'mawere yopangidwa ndi British GlaxoSmithKline Co. Human ErbB receptors ali amtundu wa I tyrosine kinase (TK) receptor banja, kuphatikizapo ErbB1 (EGFR), ErbB2 (HER2), ErbB3 (HER3), ndi ErbB4 (HER4) .The ErbB-1 (EGFR) ndi ErbB-2 (HER-2) zolandilira nthawi zambiri mopambanitsa kapena kusinthidwa zina mwa odwala khansa.Human epidermal growth factor receptor 2 (ErbB-2, HER-2) amadziwika kuti ndi oncogene yamunthu yogwirizana kwambiri ndi khansa ya m'mawere.Mawonekedwe ake apamwamba mu khansa ya m'mawere nthawi zambiri amaneneratu za metastasis ya lymph node ndi kusiyana koyipa kwa chotupa, ndi kusazindikira bwino.HER-2 ndi amodzi mwa mamolekyu omwe amawathandizira pamankhwala okhudzana ndi khansa ya m'mawere.Lapatinib imatha kuchita nthawi imodzi pa Her-1 Her-2.Zotsatira zachilengedwe za njirayi zomwe zimalepheretsa kuchulukana ndi kukula kwa maselo a chotupa ndizokulirapo kuposa kungochita chandamale chimodzi.Kuphatikizika kwa Lapatinib ndi Capecitabine kumagwiritsidwa ntchito pochiza odwala omwe ali ndi khansa ya m'mawere yapamwamba kapena ya metastatic yokhala ndi epidermal receptor2 yamunthu, yomwe idathandizidwa kale ndi anthracyclines, paclitaxel, ndi trastuzumab.Mayesero azachipatala awonetsa kuti Lapatinib imathandiziranso bwino odwala khansa yamtundu wa HER2 omwe ali ndi Herceptin kukana.
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