Lapatinib Intermediate CAS 231278-84-5 Purity >98.0% (HPLC)
Dzina la Chemical | 5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde |
Mawu ofanana ndi mawu | Lapatinib Wapakatikati 3;5- [4- [[3-Chloro-4-[(3-Fluorophenyl))methoxy]phenyl]amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5--[4-((3-Chloro-4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-Furaldehyde |
Nambala ya CAS | 231278-84-5 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C26H17ClFN3O3 |
Kulemera kwa Maselo | 473.90 |
Melting Point | 225.0 mpaka 235.0 ℃ |
Kuchulukana | 1.407±0.06 g/cm3 |
Refractive Index | 1.694 |
COA & MSDS | Likupezeka |
Chiyambi | Shanghai, China |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Wolimba Wachikasu mpaka Wachikasu |
Kuyera / Kusanthula Njira | >98.0% (HPLC) |
Melting Point | 225.0 ~ 235.0 ℃ |
Kutaya pa Kuyanika | <1.00% |
Zotsalira pa Ignition | <0.50% |
Zonse Zonyansa | <2.00% |
Zitsulo Zolemera (monga Pb) | <20ppm |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Pakati pa API (CAS 388082-77-7) |
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5--[4--[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) ndi yapakatikati ya API (CAS 388082-77-7) ).(CAS 388082-77-7) ndi mankhwala okhudza khansa ya m'mawere opangidwa ndi British GlaxoSmithKline Co. Ndi tyrosine kinase inhibitor yomwe ingalepheretse bwino ntchito ya tyrosine kinase ya epidermal growth factor receptors 1 ndi 2 (ErbB1, ErbB2).Ikhoza kuchita mwapadera m'njira zosiyanasiyana, kuonetsetsa kuti maselo a khansa ya m'mawere sangalandire zizindikiro za kukula.Imalepheretsa malo ozungulira a EGFR (ErbB-1) ndi HER2 (ErbB-2) ATP, kuteteza maselo a chotupa phosphorylation ndi kutsegula, kutsekereza zizindikiro zapansi kudzera mu homogeneity ndi heterogeneity ya EGFR (ErbB-1) ndi HER2 (ErbB-1) dimerization.
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