Lapatinib Intermediate CAS 231278-84-5 Purity >98.0% (HPLC)

Kufotokozera Kwachidule:

5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde

CAS: 231278-84-5

Kuyera: > 98.0% (HPLC)

Maonekedwe: Ufa Wotuwa Wachikasu Kupita Wachikasu

Pakati pa API (CAS 388082-77-7)

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Lapatinib Intermediates:

Chemical Properties:

Dzina la Chemical 5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde
Mawu ofanana ndi mawu Lapatinib Wapakatikati 3;5- [4- [[3-Chloro-4-[(3-Fluorophenyl))methoxy]phenyl]amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5--[4-((3-Chloro-4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-Furaldehyde
Nambala ya CAS 231278-84-5
Stock Status Mu Stock, Kupanga Kukula Mpaka Matani
Molecular Formula C26H17ClFN3O3
Kulemera kwa Maselo 473.90
Melting Point 225.0 mpaka 235.0 ℃
Kuchulukana 1.407±0.06 g/cm3
Refractive Index 1.694
COA & MSDS Likupezeka
Chiyambi Shanghai, China
Mtundu Ruifu Chemical

Zofotokozera:

Kanthu Zofotokozera
Maonekedwe Ufa Wolimba Wachikasu mpaka Wachikasu
Kuyera / Kusanthula Njira >98.0% (HPLC)
Melting Point 225.0 ~ 235.0 ℃
Kutaya pa Kuyanika <1.00%
Zotsalira pa Ignition <0.50%
Zonse Zonyansa <2.00%
Zitsulo Zolemera (monga Pb) <20ppm
Test Standard Enterprise Standard
Kugwiritsa ntchito Pakati pa API (CAS 388082-77-7)

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231278-84-5 - Ntchito:

5--[4--[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) ndi yapakatikati ya API (CAS 388082-77-7) ).(CAS 388082-77-7) ndi mankhwala okhudza khansa ya m'mawere opangidwa ndi British GlaxoSmithKline Co. Ndi tyrosine kinase inhibitor yomwe ingalepheretse bwino ntchito ya tyrosine kinase ya epidermal growth factor receptors 1 ndi 2 (ErbB1, ErbB2).Ikhoza kuchita mwapadera m'njira zosiyanasiyana, kuonetsetsa kuti maselo a khansa ya m'mawere sangalandire zizindikiro za kukula.Imalepheretsa malo ozungulira a EGFR (ErbB-1) ndi HER2 (ErbB-2) ATP, kuteteza maselo a chotupa phosphorylation ndi kutsegula, kutsekereza zizindikiro zapansi kudzera mu homogeneity ndi heterogeneity ya EGFR (ErbB-1) ndi HER2 (ErbB-1) dimerization.

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