Lapatinib Ditosylate Monohydrate CAS 388082-78-8 Purity >99.0% (HPLC)

Kufotokozera Kwachidule:

Dzina la Mankhwala: Lapatinib Ditosylate Monohydrate

CAS: 388082-78-8

Kuyera: > 99.0% (HPLC)

Maonekedwe: Ufa Wotuwa Wachikasu Mpaka Wachikasu Wa crystalline

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E-Mail: alvin@ruifuchem.com


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Lapatinib Intermediates:

Chemical Properties:

Dzina la Chemical Lapatinib Ditosylate Monohydrate
Mawu ofanana ndi mawu N--[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
Nambala ya CAS 388082-78-8
Stock Status Zilipo
Molecular Formula C29H26ClFN4O4S·2(C7H8O3S)·H2O
Kulemera kwa Maselo 943.48
COA & MSDS Likupezeka
Chiyambi Shanghai, China
Mtundu Ruifu Chemical

Zofotokozera:

Kanthu Zofotokozera
Maonekedwe Ufa Wotuwa Wachikasu Mpaka Wachikasu Wa crystalline
Kuyera / Kusanthula Njira ≥99.0% (HPLC)
Melting Point 240.0 ~ 242.0 ℃
Chinyezi (KF) 1.9-2.4%
Chidetso Chimodzi ≤0.50%
Zonse Zonyansa ≤1.00%
Zitsulo Zolemera (monga Pb) ≤20ppm
Test Standard Enterprise Standard
Kugwiritsa ntchito API;Zochizira odwala khansa ya m'mawere

Phukusi & Kusungira:

Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala

Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi

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388082-78-8 - Kugwiritsa ntchito:

Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8) ndi mchere wa ditosylate waCAS 231277-92-2, quinazoline yopangidwa, yogwira pakamwa yokhala ndi ntchito yoletsa antiineoplastic.Imalepheretsanso phosphorylation ya epidermal growth factor receptor (EGFR), ErbB2, ndi Erk-1 ndi-2 ndi AKT kinases;imalepheretsanso kuchuluka kwa mapuloteni a cyclin D m'mizere yama cell chotupa chamunthu ndi ma xenografts.EGFR ndi ErbB2 zakhala zikukhudzidwa pakukula kwa mitundu yosiyanasiyana ya chotupa.Idayambitsidwa kuti azichiza khansa ya m'mawere yapamwamba kapena metastatic HER2 (ErbB2) mwa amayi omwe adalandirapo chithandizo choyambirira.Mankhwalawa adapezeka ndikupangidwa ndi GlaxoSmithKline.

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