Lapatinib Ditosylate Monohydrate CAS 388082-78-8 Purity >99.0% (HPLC)
Dzina la Chemical | Lapatinib Ditosylate Monohydrate |
Mawu ofanana ndi mawu | N--[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine |
Nambala ya CAS | 388082-78-8 |
Stock Status | Zilipo |
Molecular Formula | C29H26ClFN4O4S·2(C7H8O3S)·H2O |
Kulemera kwa Maselo | 943.48 |
COA & MSDS | Likupezeka |
Chiyambi | Shanghai, China |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Wotuwa Wachikasu Mpaka Wachikasu Wa crystalline |
Kuyera / Kusanthula Njira | ≥99.0% (HPLC) |
Melting Point | 240.0 ~ 242.0 ℃ |
Chinyezi (KF) | 1.9-2.4% |
Chidetso Chimodzi | ≤0.50% |
Zonse Zonyansa | ≤1.00% |
Zitsulo Zolemera (monga Pb) | ≤20ppm |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | API;Zochizira odwala khansa ya m'mawere |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
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Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8) ndi mchere wa ditosylate waCAS 231277-92-2, quinazoline yopangidwa, yogwira pakamwa yokhala ndi ntchito yoletsa antiineoplastic.Imalepheretsanso phosphorylation ya epidermal growth factor receptor (EGFR), ErbB2, ndi Erk-1 ndi-2 ndi AKT kinases;imalepheretsanso kuchuluka kwa mapuloteni a cyclin D m'mizere yama cell chotupa chamunthu ndi ma xenografts.EGFR ndi ErbB2 zakhala zikukhudzidwa pakukula kwa mitundu yosiyanasiyana ya chotupa.Idayambitsidwa kuti azichiza khansa ya m'mawere yapamwamba kapena metastatic HER2 (ErbB2) mwa amayi omwe adalandirapo chithandizo choyambirira.Mankhwalawa adapezeka ndikupangidwa ndi GlaxoSmithKline.
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