4,4′-Bis(2-Bromoacetyl)biphenyl CAS 4072-67-7 Daclatasvir Dihydrochloride Intermediate Purity>98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga 4,4'-Bis(2-Bromoacetyl) biphenyl (CAS: 4072-67-7) yokhala ndi mtundu wapamwamba kwambiri.Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, ntchito zabwino kwambiri, zochepa komanso zochulukirapo zomwe zilipo.Gulani 4,4'-Bis(2-Bromoacetyl)biphenyl,Please contact: alvin@ruifuchem.com
Dzina la Chemical | 4,4'-Bis(2-Bromoacetyl) biphenyl |
Mawu ofanana ndi mawu | 4,4'-Bis(Bromoacetyl)biphenyl;1,1'-[1,1'-Biphenyl]-4,4'-diylbis[2-Bromoethan-1-one];Daclatasvir Chidetso 7 |
Stock Status | Mu Stock, Commercial Production |
Nambala ya CAS | Zithunzi za 4072-67-7 |
Molecular Formula | C16H12Br2O2 |
Kulemera kwa Maselo | 396.07g/mol |
Melting Point | 226.0 ~ 227.0 ℃ |
Kuchulukana | 1.622±0.06 g/cm3 |
COA & MSDS | Likupezeka |
Chiyambi | Shanghai, China |
Gulu | Pakati pa Daclatasvir Dihydrochloride (CAS: 1009119-65-6) |
Mtundu | Ruifu Chemical |
Zinthu | Zofotokozera | Zotsatira |
Maonekedwe | Zolimba | Zolimba |
Kuyera / Kusanthula Njira | >98.0% (HPLC) | 98.5% |
Infrared Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
1H NMR Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
Mapeto | Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa | |
Kugwiritsa ntchito | Pakati pa Daclatasvir Dihydrochloride (CAS: 1009119-65-6) |
Phukusi:Botolo la Fluorinated, thumba la Aluminiyamu zojambulazo, 25kg / Cardboard Drum, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Sungani chidebecho chotsekedwa mwamphamvu ndipo sungani m'nyumba yozizira, yowuma komanso yolowera mpweya wabwino kutali ndi zinthu zomwe sizingagwirizane.Tetezani ku kuwala ndi chinyezi.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
4,4'-Bis (2-Bromoacetyl) biphenyl (CAS: 4072-67-7) ndi yapakatikati ya Daclatasvir Dihydrochloride (CAS: 1009119-65-6).
Daclatasvir Dihydrochloride (Daklinza) ndi inhibitor ya kachilombo ka hepatitis C (HCV) NS5A yomwe imakhala yothandiza pochiza matenda a genotype 3 aakulu a hepatitis C.
Pa Julayi 24, 2015, a FDA adavomereza mankhwala osatha a hepatitis C (Bristol-Myers Squibb) kuti azitha kutsatsa.
Dongosolo lovomerezeka la FDA la Daklinza (Bristol-Myers Squibb) ladutsa mopotoka.Idakanidwa kamodzi ndi FDA, koma pomaliza idavomerezedwa pakati pa 2015.A FDA adavomereza kuphatikiza kwa Daklinza ndi Sofosbuvir pochiza odwala amtundu wa 3 wa hepatitis C.
M'malo mwake, kale asanavomerezedwe ndi FDA, Daklinza idavomerezedwa kuti igulitsidwe ku Japan, European Union ndi South Korea ndi mayiko ena.Mu 2014, gawo la zaumoyo ku Japan lidavomereza kugwiritsa ntchito Daklinza ndi Asunaprevir (Sunvepra) pochiza matenda a genotype 1.European Union inavomerezanso kuti Daclatasvir igwiritsidwe ntchito pamodzi ndi mankhwala ena pochiza HCV genotypes 1, 2, 3 ndi 4 mu 2014. Daclatasvir ndiye woyamba NS5A complex inhibitor wovomerezedwa ndi European Union (EU).Mukagwiritsidwa ntchito limodzi ndi mankhwala ena, poyerekeza ndi kuphatikiza kwa interferon ndi ribavirin komwe kumatenga milungu 48, mankhwalawa amakhala ndi nthawi yayitali (masabata 12 kapena masabata 24).
Daclathavir monotherapy ndiyosavomerezeka, njira yodziwika bwino yomwe ilipo tsopano ndi mankhwala ophatikiza a Dacastavir+ Sofosbuvir, omwe amadziwika ndi mphamvu yabwino, SVR yapamwamba, zotsatirapo zing'onozing'ono komanso kufupikitsa njira yamankhwala kuposa njira zina.