Apixaban Intermediate CAS 545445-44-1 Chiyero >98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-one (CAS: 545445) -44-1) ndi khalidwe lapamwamba, lapakati la Apixaban (CAS: 503612-47-3).Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, ntchito zabwino kwambiri, zochepa komanso zochulukirapo zomwe zilipo.Gulani Apixaban Intermediates,Please contact: alvin@ruifuchem.com
| Dzina la Chemical | 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-chimodzi |
| Mawu ofanana ndi mawu | Apixaban Wapakatikati 1;5,6-Dihydro-3- (4-Morpholinyl) -1-[4-(2-Oxo-1-Piperidinyl) phenyl] -2 (1H) -Pyridinone;5-Morpholin-4-yl-1--[4-(2-Oxopiperidin-1-yl) phenyl] -2,3-Dihydropyridin-6-imodzi;Apixaban Impurity A |
| Stock Status | Mu Stock, Commercial Production |
| Nambala ya CAS | 545445-44-1 |
| Molecular Formula | C20H25N3O3 |
| Kulemera kwa Maselo | 355.43 g / mol |
| Melting Point | > 199 ℃ (Dec.) |
| Kuchulukana | 1.267g/mL |
| COA & MSDS | Likupezeka |
| Chiyambi | Shanghai, China |
| Gulu | Wapakatikati wa Apixaban (CAS: 503612-47-3) |
| Mtundu | Ruifu Chemical |
| Zinthu | Zofotokozera | Zotsatira |
| Maonekedwe | Ufa Wachikasu Wowala | Ufa Wachikasu Wowala |
| Kutaya pa Kuyanika | <0.50% | 0.16% |
| Zotsalira pa Ignition | <0.20% | 0.07% |
| Kuyera / Kusanthula Njira | >98.0% (HPLC Area) | 99.12% |
| Chidetso Chilichonse Chamunthu | <0.50% | <0.50% |
| Zonse Zonyansa | <2.00% | 0.88% |
| 1H NMR Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
| LC-MS ya Kuzindikiritsa | Zimagwirizana | Zimagwirizana |
| Mapeto | Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa | |
| Kugwiritsa ntchito | Wapakatikati wa Apixaban (CAS: 503612-47-3) | |
Phukusi:Botolo la Fluorinated, thumba la Aluminiyamu zojambulazo, 25kg / Cardboard Drum, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Sungani chidebecho chotsekedwa mwamphamvu ndipo sungani m'nyumba yozizira, yowuma komanso yolowera mpweya wabwino kutali ndi zinthu zomwe sizingagwirizane.Tetezani ku kuwala ndi chinyezi.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-one (CAS: 545445-44-1) ndi yapakatikati ya Apixaban (CAS: 503612-47-3).
Apixaban ndi mtundu watsopano wa oral Xa factor inhibitor wopangidwa pamodzi ndi Bristol-Myers Squibb ndi Pfizer.Dzina lamalonda ndi Eratol, lomwe ndi mtundu watsopano wa anticoagulant oral.Poletsa coagulation factor Xa, Apixaban imatha kuletsa kupanga thrombin ndi thrombosis.Pa Epulo 26, 2007, Bristol-Myers Squibb adalumikizana ndi Pfizer kuti alengeze mgwirizano pakupanga anticoagulant yatsopano yapakamwa ya Apixaban ya Bristol-Myers Squibb ngati njira yopititsira patsogolo ya Warfarin.Mu May 2011, Apixaban anali woyamba kuvomereza kupewa venous thrombosis kwa odwala akuluakulu omwe amachitidwa opaleshoni yosankha m'chiuno kapena mawondo m'mayiko a 27 EU, Iceland ndi Norway.Pa November 20, 2012, European Commission inavomereza Ererto (Apixaban) pofuna kupewa sitiroko ndi systemic embolism kwa odwala akuluakulu omwe ali ndi vuto la non-valvular atrial fibrillation (NVAF) ndi chimodzi kapena zingapo zoopsa.Pambuyo pake, a Canadian Food and Drug Administration, Japan, ndi US FDA adavomereza Ererto (Apixaban) pofuna kupewa sitiroko ndi systemic embolism mwa odwala akuluakulu omwe ali ndi vuto lopanda valvular atrial fibrillation (NVAF) ndi chimodzi kapena zingapo zoopsa.Pa Epulo 12, 2013, mankhwala atsopano a anticoagulant Eloto (ELIQUIS) (Apixaban) opangidwa ndi Bristol-Myers Squibb ndi Pfizer adalengezedwa kuti alembedwa ku China.
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