5-Amino-3-(Trifluoromethyl)picolinonitrile CAS 573762-62-6 Apalutamide Intermediate Purity>98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga 5-Amino-3-(Trifluoromethyl)picolinonitrile (CAS: 573762-62-6) yokhala ndi mawonekedwe apamwamba, apakatikati a Apalutamide (CAS: 956104-40-8).Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, ntchito zabwino kwambiri, zochepa komanso zochulukirapo zomwe zilipo.Gulani Apalutamide Intermediates,Please contact: alvin@ruifuchem.com
| Dzina la Chemical | 5-Amino-3-(Trifluoromethyl)picolinonitrile |
| Mawu ofanana ndi mawu | 5-Amino-3-(Trifluoromethyl)pyridine-2-Carbonitrile;5-Amino-3- (Trifluoromethyl) 2-Cyanopyridine;5-Amino-2-Cyano-3-(Trifluoromethyl)pyridine;Apalutamide Impurity 10 |
| Stock Status | Mu Stock, Commercial Production |
| Nambala ya CAS | 573762-62-6 |
| Molecular Formula | Chithunzi cha C7H4F3N3 |
| Kulemera kwa Maselo | 187.12 g / mol |
| Kuchulukana | 1.45±0.10 g/cm3 |
| COA & MSDS | Likupezeka |
| Chiyambi | Shanghai, China |
| Kalasi Yowopsa | 6.1 |
| Packing Group | Ⅲ |
| Gulu | Wapakatikati wa Apalutamide (CAS: 956104-40-8) |
| Mtundu | Ruifu Chemical |
| Zinthu | Miyezo Yoyendera | Zotsatira |
| Maonekedwe | Yellow Yopepuka mpaka Yellow Yolimba | Zimagwirizana |
| Madzi ndi Karl Fischer | <0.50% | 0.35% |
| Kuyera / Kusanthula Njira | >98.0% (HPLC) | 99.03% |
| Infrared Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
| 1H NMR Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
| Mapeto | Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa | |
| Kugwiritsa ntchito | Wapakatikati wa Apalutamide (CAS: 956104-40-8) | |
Phukusi:Botolo la Fluorinated, thumba la Aluminiyamu zojambulazo, 25kg / Cardboard Drum, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Sungani chidebecho chotsekedwa mwamphamvu ndipo sungani m'nyumba yozizira, yowuma komanso yolowera mpweya wabwino kutali ndi zinthu zomwe sizingagwirizane.Tetezani ku kuwala ndi chinyezi.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
5-Amino-3- (Trifluoromethyl) picolinonitrile (CAS: 573762-62-6), ndi pyridine heterocyclic organic compound, yomwe ingagwiritsidwe ntchito ngati mankhwala apakati.5-Amino-3-(Trifluoromethyl)picolinonitrile ndi apalutamide wapakatikati (CAS: 956104-40-8).Apalutamide ndi antiandrogen ya m'badwo wachiwiri yomwe imagwiritsidwa ntchito pochiza khansa ya prostate.Ndiwotsutsa wamphamvu wa androgen receptor ndi IC50 mtengo wa 16 nM.Amamanga ma androgen receptors, motero amalepheretsa kusuntha kwa nyukiliya, kumanga kwa DNA ndi kutsegulira kwa transcriptal.Apalutamide ali ndi chithandizo chamankhwala mu khansa ya prostate yopanda metastatic, yolimbana ndi castration.
Apalutamide amagwiritsidwa ntchito pochiza mitundu ina ya khansa ya prostate yolimbana ndi kutayika kapena khansa ya prostate yomwe siinafalikire ku ziwalo zina za thupi, koma sanathandizidwe ndi mankhwala ena.Apalutamide ali m'gulu la mankhwala otchedwa androgen receptor inhibitors.Zimagwira ntchito poletsa zotsatira za androgen kuti asiye kukula ndi kufalikira kwa maselo a khansa.Pa Seputembara 17, 2019, bungwe la Food and Drug Administration lidavomereza Apalutamide (ERLEADA, Janssen Biotech, Inc) kwa odwala omwe ali ndi metastatic castration-sensitive cancer prostate (mCSPC).Apalutamide idavomerezedwa koyamba mu 2018 kwa odwala omwe ali ndi khansa ya prostate yosagwirizana ndi metastatic castration.
