Trelagliptin Succinate Intermediate CAS 865759-24-6 Chiyero >98.0% (HPLC) Chithunzi Chowonetsedwa

Trelagliptin Succinate Yapakatikati CAS 865759-24-6 Chiyero >98.0% (HPLC)

Kufotokozera Kwachidule:

Trelagliptin Succinate Intermediate-int D

CAS: 865759-24-6

Kuyera: > 98.0% (HPLC)

Maonekedwe: Yoyera-Yoyera mpaka Kuwala kwa Yellow Crystal

Wapakatikati wa Trelagliptin Succinate (CAS: 1029877-94-8) pochiza Type 2 Diabetes

Lumikizanani ndi Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zogwirizana nazo

Zolemba Zamalonda

Kufotokozera:

Zogwirizana ndi Zamalonda za Trelagliptin Succinate:
6-Chloro-3-Methyluracil CAS 4318-56-3
2-Cyano-5-Flurobenzyl Bromide CAS 421552-12-7
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
Trelagliptin Succinate Yapakatikati-int D CAS 865759-24-6
Trelagliptin Succinate CAS 1029877-94-8
Please contact: alvin@ruifuchem.com

Chemical Properties:

Dzina la Chemical	Trelagliptin Succinate Intermediate-int D
Mawu ofanana ndi mawu	2-((6-Chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1 (2H)-yl)Methyl) -4-fluorobenzonitrile;2- [(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-4-fluorobenzonitrile
Chidetso	Chidetso cha Trelagliptin 17
Stock Status	Mu Stock, Commercial Scale
Nambala ya CAS	865759-24-6
Molecular Formula	C13H9ClFN3O2
Kulemera kwa Maselo	293.68 g / mol
Kuchulukana	1.49±0.10 g/cm3
Kusungirako Temp.	Malo Ozizira & Owuma
COA & MSDS	Likupezeka
Mtundu	Ruifu Chemical

Zofotokozera:

Zinthu	Miyezo Yoyendera	Zotsatira
Maonekedwe	Woyera-Woyera mpaka Kuwala Yellow Crystal	Zimagwirizana
Chizindikiritso
Mtengo wa HPLC	Nthawi yosungitsa pachimake chachikulu cha mayeso imagwirizana ndi muyezo	Zimagwirizana
IR - Infrared Spectrum	IR mayamwidwe sipekitiramu zitsanzo ndi muyezo ndi concordant	Zimagwirizana
Kuyendera
Kutaya pa Kuyanika	<0.50%	0.3%
Zonse Zonyansa	<2.00%	Zimagwirizana
Kuyera / Kusanthula Njira	>98.0% (HPLC)	99.1%
Mapeto	Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zanenedwa

Phukusi/kusungirako/Manyamulidwe:

Phukusi:Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zomata pamalo ozizira ndi owuma komanso olowera mpweya wabwino kutali ndi zinthu zosagwirizana.Tetezani ku kuwala ndi chinyezi.Pewani kuwala;Zopanda mpweya.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.

Ubwino:

Mphamvu Zokwanira: Malo okwanira ndi akatswiri

Utumiki Waukatswiri: Ntchito imodzi yosiya kugula

Phukusi la OEM: Phukusi lamwambo ndi zolemba zilipo

Kutumiza Mwachangu: Ngati mkati mwa katundu, kuperekedwa kwamasiku atatu kumatsimikizika

Zinthu Zokhazikika: Khalani ndi katundu wokwanira

Thandizo laukadaulo: Yankho laukadaulo likupezeka

Custom Synthesis Service: Kuchokera pa magalamu mpaka ma kilos

Ubwino Wapamwamba: Anakhazikitsa dongosolo lathunthu lotsimikizira zaubwino

FAQ:

Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.

Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.

Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.

UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.

Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.

MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.

Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.

Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.

Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.

Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.

Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.

Ntchito:

2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile (CAS: 865759-24-6) amagwiritsidwa ntchito ngati mankhwala. wapakatikati wa Trelagliptin Succinate (CAS: 1029877-94-8).Trelagliptin Succinate, yopangidwa ndi Takeda, Japan, yomwe idakhazikitsidwa mu Marichi 2015, pansi pa dzina lazamalonda la Zafatek, imagwiritsidwa ntchito pochiza matenda amtundu wa 2.Trelagliptin ndi ultra-acting dipeptidyl peptidase IV (DPP-4) inhibitor mwa kusankha komanso mosalekeza kuletsa DPP-4 kuwongolera kuchuluka kwa shuga m'magazi.Trelagliptin ndiye mankhwala oyamba a hypoglycemic pa sabata pamsika, ndipo zoletsa zofananira za DPP-4 pamsika zimafunika kutengedwa kamodzi patsiku.Ubwino wamankhwala a Zafatek mosakayikira upereka njira zothandizira odwala matenda ashuga.Zikuyembekezeka kupititsa patsogolo kumasuka komanso kutsata kwa odwala.pa Marichi 26, 2015, chimphona chamankhwala ku Japan Takeda adalengeza kuti mankhwala atsopano a shuga a Zafatek adavomerezedwa ndi Unduna wa Zaumoyo, Ntchito ndi Ubwino ku Japan (MHLW) pochiza matenda amtundu wachiwiri.Chivomerezochi chikuwonetsa kuti Zafatek kukhala mankhwala oyamba amkamwa a hypoglycemic pamsika padziko lonse lapansi, ndikuyimiranso blockbuster yomwe Takeda adatsika pamsika wa shuga.
Trelagliptin ndi choletsa cha dipeptidyl peptidase IV (DPP-4) kamodzi pa sabata chomwe chimawongolera kuchuluka kwa shuga m'magazi mwa kusankha komanso mosalekeza kuletsa DPP-4.DPP-4 ndi puloteni yomwe imatha kuyambitsa incretin (glucagon-like peptide -1 (GLP-1) ndi glucose-dependent insulinotropic polypeptide (GIP)), yomwe imagwira ntchito yofunika kwambiri pakuwongolera shuga wamagazi.Kuletsa kwa DPP-4 kumatha kukulitsa katulutsidwe ka insulini yodalira shuga m'magazi, motero kuwongolera kuchuluka kwa shuga m'magazi.Kupereka kwa Trelagliptin NDA kumatengera mphamvu komanso chitetezo cham'mayesero angapo azachipatala a gawo lachitatu la odwala aku Japan omwe ali ndi matenda a shuga a 2.Kugwira ntchito kwa Trelagliptin kwatsimikiziridwa m'mayesero onse, ndipo ili ndi chitetezo chabwino komanso kulekerera.Kuwongolera kwa Trelagliptin kamodzi pa sabata kumatha kuwongolera shuga m'magazi ndipo kukuyembekezeka kupititsa patsogolo kutsata kwamankhwala kwa odwala.