Enzalutamide CAS 915087-33-1 Purity>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ndiye wopanga wamkulu wa Enzalutamide (CAS: 915087-33-1) wokhala ndipamwamba kwambiri.Ruifu Chemical imatha kubweretsa padziko lonse lapansi, mtengo wampikisano, ntchito zabwino kwambiri, zochepa komanso zochulukirapo zomwe zilipo.Gulani Enzalutamide (CAS: 915087-33-1),Please contact: alvin@ruifuchem.com
Dzina la Chemical | Enzalutamide |
Mawu ofanana ndi mawu | MDV-3100;MDV 3100;4--[3---Cyano-3-(Trifluoromethyl)phenyl]-5,5-Dimethyl-4-Oxo-2-Thioxo-1-Imidazolidinyl]-2-Fluoro-N-Methylbenzamide |
Stock Status | Mu Stock, Mphamvu Yopanga 50 kgs pamwezi |
Nambala ya CAS | 915087-33-1 |
Molecular Formula | Chithunzi cha C21H16F4N4O2S |
Kulemera kwa Maselo | 464.44 g / mol |
Melting Point | 198.0 ~ 200.0 ℃ |
Kuchulukana | 1.49 |
COA & MSDS | Likupezeka |
Chiyambi | Shanghai, China |
Mtundu | Ruifu Chemical |
Zinthu | Zofotokozera | Zotsatira |
Maonekedwe | Ufa Wolimba mpaka Woyera | Zimagwirizana |
Kuyera / Kusanthula Njira | >99.0% (HPLC) | 99.57% |
Madzi ndi Karl Fischer | <0.50% | 0.23% |
Zotsalira pa Ignition | <0.10% | 0.06% |
Zitsulo Zolemera (Pb) | ≤20ppm | <10ppm |
Zogwirizana nazo | ||
Max.Chidetso Chimodzi | <0.50% | <0.50% |
Zonse Zonyansa | <1.00% | 0.43% |
Infrared Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
1H NMR Spectrum | Zogwirizana ndi Kapangidwe | Zimagwirizana |
Mapeto | Chogulitsacho chayesedwa ndipo chikugwirizana ndi zomwe zaperekedwa |
Phukusi:Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi zofunika kasitomala.
Mkhalidwe Wosungira:Sungani chidebecho chotsekedwa mwamphamvu ndikusunga pamalo ozizira, owuma (2~8 ℃) komanso molowera mpweya wabwino kutali ndi zinthu zomwe sizingagwirizane.Tetezani ku kuwala ndi chinyezi.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
Enzalutamide (CAS: 915087-33-1) ndi androgen-receptor antagonist (AR) ndi IC50 ya 36 nM, yomwe imalepheretsa androgens kumangiriza ku receptor ya androgen ndikulepheretsa kusuntha kwa nyukiliya ndi co-activator recruitment ya ligand-receptor complex.Enzalutamide yawonetsedwanso kuti imapangitsa chotupa cell apoptosis, ndipo ilibe zochita za agonist.Enzalutamide ndi woimira chithandizo cha khansa ya prostate yolimbana ndi castration.Enzalutamide, ndi m'badwo wachiwiri wa androgen receptor (AR) signing inhibitor.Imatha kuletsa kumangirira kwa androgens ku AR, AR nyukiliya translocation, ndi kuyanjana kwa AR ndi DNA.Mu Ogasiti 2012, FDA idavomereza Enzalutamide, yogulitsidwa ndi Medivation ndi Astellas Pharma US kuti azichiza metastatic castration-resistant prostate cancer (CRPC), makamaka kwa odwala omwe adalandirapo kale Docetaxel.