Cetrorelix Acetate CAS 130143-01-0 GnRH Antagonist Peptide Purity (HPLC) ≥98.0% High Quality

Kufotokozera Kwachidule:

Dzina la Chemical: Cetrorelix Acetate

CAS: 130143-01-0

Maonekedwe: Ufa Woyera

Peptide Purity (HPLC): ≥98.0%

Synthetic Antagonist wa GnRH Receptor

GMP Peptides, API, High Quality

Lumikizanani ndi Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com 


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Kufotokozera:

Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga Cetrorelix Acetate (CAS: 130143-01-0) yokhala ndipamwamba kwambiri.Cetrorelix Acetate ndi mdani wa gonadotropin-release hormone (GnRH).Ruifu Chemical imapereka ma peptides angapo a GMP.Ruifu atha kubweretsa padziko lonse lapansi, mtengo wampikisano, zochepa komanso zochulukirapo zomwe zilipo.Gulani Cetrorelix Acetate,Please contact: alvin@ruifuchem.com

Chemical Properties:

Dzina la Chemical Cetrorelix Acetate
Mawu ofanana ndi mawu N-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-4-Chloro-D-Phenylalanyl-3-(3-Pyridinyl)-D-Alanyl-L-Seryl-L-Tyrosyl-N5-(Aminocarbonyl)- D-Ornithyl-L-Leucyl-L-Arginyl-L-Prolyl-D-Alaninamide Diacetate;NS-75A Diacetate;SB-075 Diacetate
Zotsatizana Ac-3-(2-naphthyl)-D-Ala-4-Chloro-D-Phe-3(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala -NH2
Nambala ya CAS 130143-01-0
Stock Status Mu Stock, Production Scale Up to Kilograms
Molecular Formula Chithunzi cha C70H92N17O14
Kulemera kwa Maselo 1551.16
Kusungirako Temp. Malo Ozizira & Owuma (-20 ℃).Firiji
Shelf Life > Zaka 2 Ngati Zasungidwa Bwino
Gulu GMP Peptides
Chikalata COA, MS, HPLC, NMR, MSDS, etc.
Mtundu Ruifu Chemical

Zofotokozera:

Kanthu Zofotokozera
Maonekedwe Ufa Woyera
Peptide Purity (wolemba HPLC) ≥98.0% (mwa Area Integration)
Zolemba za Peptide ≥80.0% (mwa %N)
Kupanga kwa Amino Acid 10% ya Theetical
Zinthu za Acetate ≤10.0% (mwa HPLC)
Zithunzi za TFA ≤1.0%
Chidetso Chimodzi ≤1.0% (mwa HPLC)
Zomwe zili m'madzi (Karl Fischer) ≤8.0%
Kuyesa 95.0~105.0% (Wopanda Ahydrous, Acetic Acid-Free)
MS Zosasintha
Test Standard Enterprise Standard
Zofunikira Zotumiza Zikwama za Ice, Matumba a Desiccant
Chiyambi Chazogulitsa Zopangidwa
Chidwi Zofufuza Zokha, Osati Zogwiritsa Ntchito Anthu
Kugwiritsa ntchito Synthetic Antagonist wa GnRH Receptor

Phukusi & Kusungira:

Phukusi:Botolo lapulasitiki (lopatulidwira kulongedza peptide) kapena mbale yagalasi, kuchuluka kwake malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Sungani m'mitsuko yomata pamalo ozizira komanso owuma (2~8 ℃) kutali ndi zinthu zomwe sizingagwirizane.Tetezani ku kuwala ndi chinyezi.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.

Ubwino:

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Ntchito:

Cetrorelix Acetate (CAS 130143-01-0) ndi gonadotropin-release hormone (GnRH) yomwe imagulitsidwa makamaka pansi pa dzina la Cetrotide.Decapeptide yopangidwa, imagwiritsidwa ntchito pothandizira kubereka kuti alepheretse kuchuluka kwa mahomoni a luteinizing.Mankhwalawa amagwira ntchito poletsa zochita za GnRH pa pituitary, motero amalepheretsa kupanga ndi kuchitapo kanthu kwa hormone ya luteinizing (LH) ndi follicle-stimulating hormone (FSH).Cetrorelix Acetate imapangidwa ndi mitundu yosiyanasiyana ya ma amino acid omwe siachilengedwe omwe amalepheretsa kutulutsa msanga kwa ovulation m'mayesero azachipatala, zomwe zimapangitsa kuti pakhale kusonkhanitsa ovulation ndikuthandizira chithandizo chaukadaulo waubereki kwa odwala omwe akukhudzidwa ndi kukondoweza kwa ovarian.
Chizindikiro cha Cetrorelix Acetate ndi mahomoni ochita kupanga omwe amaletsa zotsatira za gonadotropin-release hormone (GnRH).Mu ukadaulo wothandizira kubereka, mwa odwala omwe ali ndi kukondoweza kwa ovarian, amapewa kutulutsa msanga.
Pharmacological action Cetrorelix Acetate ndi mdani wa gonadotropin-release hormone (GnRH).GnRH imatha kumangirira ku membrane zolandilira ma cell a pituitary.Cetrorelix acetate imamangiriza pama receptor awa ndi GnRH yokhazikika, motero modalira mlingo kulepheretsa kutulutsa kwa luteinizing hormone (LH) ndi follicle stimulating hormone (FSH) ndi adenohypophysis.Zotsatira zoletsa zidapangidwa nthawi yomweyo pambuyo pa makonzedwe a cetrorelix acetate, ndipo zoletsa zimatha kusungidwa ndi chithandizo chopitilira.kwa amayi, Cetrorelix Acetate imatha kuchedwetsa nsonga ya LH, potero imachedwetsa ovulation.Kwa amayi omwe ali ndi vuto la ovarian, nthawi yochitapo kanthu inali yodalira mlingo.Mlingo umodzi wa cetrorelix 3mg unkaganiziridwa kuti umakhala ndi zotsatira zolepheretsa osachepera masiku 4, ndi zotsatira zoletsa pafupifupi 70% pa Tsiku 4. Kubwereza mobwerezabwereza kwa cetrorelix acetate 0.25mg maola onse a 24 akhoza kukhalabe ndi zotsatira zake.Mphamvu yotsutsa mahomoni ya Cetrorelix Acetate idasinthidwa kotheratu kumapeto kwa chithandizo cha nyama ndi anthu.
Biological zochitika Cetrorelix Acetate ndi mdani wamphamvu wa GnRH receptor ndi IC50 mtengo wa 1.21 nM.
Cholinga cha IC50: 1.21 nM GnRH.

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