α-Cyclodextrin (α-CD) CAS 10016-20-3 Excipients Pharmaceutical
Ruifu Chemical ndi amene amapanga α-Cyclodextrin (α-CD) (CAS: 10016-20-3) yokhala ndi khalidwe lapamwamba.Ruifu Chemical amapereka pharma grade cyclodextrins, othandizira mankhwala.Ruifu Chemical imatha kupereka zoperekera padziko lonse lapansi, zochepa komanso zochulukirapo zomwe zilipo.Gulani α-Cyclodextrin,Please contact: alvin@ruifuchem.com
Dzina la Chemical | α-Cyclodextrin |
Mawu ofanana ndi mawu | α-CD;C;Alfadex;alpha-Dextrin;α-Dextrin;Cyclohexapentylose;Cavamax W6;Schardinger α-Dextrin;α-Schardinger Dextrin;Schardinger alpha-Dextrin;Cyclomaltohexaose;Cyclohexaamylose |
Stock Status | Mu Stock, Commercial Production |
Nambala ya CAS | 10016-20-3 |
Molecular Formula | C |
Kulemera kwa Maselo | g/mol |
Melting Point | >278℃(dec.) (lit.) |
Boiling Point | ℃ |
Pophulikira | ℃ |
Kuchulukana | |
Refractive Index n20/D | 1 |
Zomverera | Hygroscopic.Imamva Kutentha, Kuwala, Kusamva Chinyezi |
Kusungunuka kwamadzi | Zosungunuka mu Madzi |
Kusungunuka | Zosungunuka mkati |
Kukhazikika | Wokhazikika.Zoyaka.Zosagwirizana Ndi Oxidizing Agents Amphamvu. |
COA & MSDS | Likupezeka |
Zitsanzo Zaulere | Likupezeka |
Chiyambi | Shanghai, China |
Gulu | Excipients mankhwala;Zakudya Zowonjezera |
Mtundu | Ruifu Chemical |
Zinthu | Zofotokozera | Zotsatira |
Maonekedwe | Ufa Woyera kapena Wapafupifupi Waamorphous kapena Crystalline | Zimagwirizana |
Kusungunuka | Zosungunuka Mwaulere mu Madzi ndi Propylene Glycol, Zosasungunuka mu Ethanol ndi Methylene Chloride | Zimagwirizana |
kukhazikitsidwa kwa HPLC | Nthawi yosungirako pachimake chachikulu cha yankho lachitsanzo chimafanana ndi yankho lokhazikika. | Zimagwirizana |
Iodine Test Solution | Madzi a Yellow-Brown Precipitate Apangidwa | Zimagwirizana |
Kuyesa | 98.0% ~ 101.0% (Yowerengedwa pa Maziko Ouma) | 100.0% |
Kusinthasintha Kwachindunji [a]20/D | +147.0° kufika +152.0°(C=1 mu H2O) (Calcd. pa Anh. Substance) | + 148.2 ° |
Kumveka & Mtundu wa Solution | 10mg/ml Water Solution ndi Yomveka komanso Yopanda Mtundu | Zimagwirizana |
Malire a Zinthu Zomwe Zimayamwa Kuwala | ≤0.10 (230 nm~350 nm) ≤0.05 (350 nm~750 nm) | Zimagwirizana |
Kutsimikiza kwa Madzi | ≤11.0% | 9.9% |
Zotsalira pa Ignition | ≤0.10% | 0.07% |
Zitsulo Zolemera | ≤5ppm | <5ppm |
Mchere wa Arsenic (Monga) | ≤1.3ppm | <1.3ppm |
Kuchepetsa Shuga | ≤0.20% | 0.16% |
Zogwirizana nazo | ||
Betadex Cyclodextrin | ≤0.25% | N/D |
Gamma Cyclodextrin | ≤0.25% | N/D |
Zina Zogwirizana | ≤0.50% | N/D |
pH | 5.0-8.0 | 6.2 |
Mayeso a Microbiological | ||
Total Aerobic Microbial Counts | ≤1000cfu/g | 30cfu/g |
Kuchuluka kwa Molds & Yeasts Kuwerengera | ≤50cfu/g | <50cfu/g |
Escherichia Coli | Kulibe | Kulibe |
Salmonella | Kulibe | Kulibe |
Infrared Spectrum | Zimagwirizana ndi Kapangidwe | Zimagwirizana |
Test Standard | Chithunzi cha USP41-NF36 |
Phukusi:0.5kg//chikwama, 1kg/thumba, 2kg/thumba, 10kg/thumba, 25kg/Drum, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Sungani chidebecho chotsekedwa mwamphamvu ndipo sungani m'nyumba yozizira, yowuma komanso yolowera mpweya wabwino kutali ndi zinthu zomwe sizingagwirizane.Tetezani ku kuwala ndi chinyezi.Zosagwirizana ndi ma oxidizing amphamvu.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi ndege, ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
Zizindikiro Zowopsa Xi - Zokwiyitsa
Zizindikiro Zowopsa R36 - Zokhumudwitsa m'maso
R36/37/38 - Zokwiyitsa maso, kupuma komanso khungu.
Kufotokozera Zachitetezo S26 - Mukakhudzana ndi maso, yambani nthawi yomweyo ndi madzi ambiri ndikupempha upangiri wamankhwala.
S36 - Valani zovala zoyenera zodzitetezera.
WGK Germany 3
RTECS GU2292000
TSCA Inde
HS kodi 3505100000
α-Cyclodextrin (α-CD) (CAS: 10016-20-3)ndi saccharide yosachepetsa yomwe imakhala ndi mayunitsi asanu ndi limodzi a shuga olumikizidwa ndi ma alpha-1.4 bond.Amapangidwa ndi zochita za cyclodextrin glucosyl transferase pa syrups hydrolysed starch.Mphuno ya alpha-Cyclodextrin ndi yocheperapo kuposa beta-Cyclodextrin, kotero imagwiritsidwa ntchito kulola kupanga mapangidwe ophatikizika okhala ndi mamolekyu ang'onoang'ono.Digiri ya solubility ya Alpha-Cyclodextrin m'madzi ndi 14.5 g/100ml @25°C, kotero kuti pafunika kusungunuka kwambiri kwa cyclodextrin.
Alpha-cyclodextrin amagwiritsidwa ntchito kwambiri mu mankhwala, chakudya, kukoma ndi zodzoladzola.Alpha-cyclodextrin imagwiritsidwanso ntchito kwambiri m'munda wa mankhwala ophera tizilombo komanso kukonza kagayidwe kazakudya ndikuwonjezera kuchuluka kwa mbewu.Makamaka cyclodextrin ndi ramification yake yomwe yapangidwa ndi zaka izi, ena mwa iwo ndi ofunikira solutizer, stablizer, kutulutsa kapena zida zothandizira za Entericcoated mankhwala, zina mwazo ndi zida za organic synthetical macromolecular stuff.
Chakudya cha Alpha cyclodextrin chokhala ndi mayunitsi 6 a shuga ali ndi kabowo kakang'ono kwambiri ka cyclodextrins.Ndiwofunika kusungunula, kukhazikika kapena kutulutsa mamolekyu ang'onoang'ono, mwachitsanzo, kulemera kwa maselo, kukoma kapena kununkhira kosakaniza.Chakudya cha Alpha cyclodextrin chikudziwitsidwa ku makampani azakudya monga chakudya chatsopano chosungunuka chokhala ndi zinthu zokhutiritsa.
Cyclodextrin ili ndi dzenje pakatikati pa kapangidwe ka mphete, ndi atomu ya oxygen momwe -CH- imamangiriza ku glucoside.Ndi sulfure-aqueous, ndipo magulu a hydroxyl pa 2, 3 ndi 6 malo a shuga ndi hydrophilic.Itha kugwiritsidwa ntchito kusokoneza mamolekyu ena kukhala ophatikizika ndi mphamvu yofooka ya van der Waals.Zinthu zambiri zimatha kuzunguliridwa ndi cyclodextrins, kuphatikiza mpweya wabwino, ma halogen, utoto, zonunkhira, mankhwala, zakudya, mankhwala ophera tizilombo komanso zoteteza.Pambuyo encapsulation, kukhazikika kwake, kusasunthika, kusungunuka ndi reactivity bwino.Mphamvu yapadera ya Cyclodextrin imapangitsa kuti ikhale yogwiritsidwa ntchito kwambiri.
1. Kugwiritsiridwa ntchito kwa Cyclodextrin m'makampani opanga mankhwala kungapangitse encapsulation (encapsulation) ndi mankhwala osokoneza bongo, omwe angapangitse (1) Mankhwala osakhazikika kukhala okhazikika;(2) Deliquescence, adhesion kapena madzi mankhwala powderization;(3) Mankhwala osasungunuka kapena osasungunuka amatha kusungunuka (solubilized), etc.
2. Kugwiritsa ntchito mankhwala ophera tizilombo a cyclodextrin encapsulation stabilization, mankhwala ena ophera tizilombo amatha kusungidwa ndikuwongolera mphamvu ya mankhwala ophera tizilombo.
3. Zomwe zimagwiritsidwa ntchito m'makampani a zakudya za cyclodextrin zimagwiritsidwa ntchito muzakudya, zimakhala ndi zotsatirazi: (1) Kuchotsa ndi kuphimba fungo lapadera;(2) Kuwongolera ndi kuwongolera kwa kapangidwe ka minofu yazakudya;(3) kuchepetsa ndi kuchotsa kukoma kowawa;(4) Antioxidant zotsatira;(5) Kusunga ndi kukhathamiritsa kwa kukoma.
4. Kugwiritsiridwa ntchito kwa Cyclodextrin m'makampani opanga mankhwala a tsiku ndi tsiku pakupanga zodzoladzola kungagwiritsidwenso ntchito ngati emulsifier ndi kuwongolera khalidwe.Lilinso ndi deodorization (monga kuwonjezera halitosis) ndi zotsatira antiseptic, angagwiritsidwe ntchito mankhwala otsukira mano, mano ufa kupanga.
5. Zina zomwe zimagwiritsidwa ntchito poteteza chilengedwe zitha kugwiritsidwa ntchito ngati mankhwala opangira zimbudzi zamafuta.Njira yamadzimadzi ya Cyclodextrin imagwiritsidwa ntchito kuyeretsa thanki yamafuta, ndipo madzi otayika amatha kubwezeredwa ndikuthandizidwa kuti apeze mafuta.
6. Kugwiritsa ntchito cyclodextrin mu chemistry Cyclodextrin ndi mankhwala ofunika kwambiri.Pamene ilipo, mphamvu ya fluorescence ya fluorochrome idzawonjezeka kwambiri, kotero ingagwiritsidwe ntchito pofufuza mapuloteni ndi amino acid.Angagwiritsidwenso ntchito kulekanitsa unyolo wautali mankhwala organic, racemes, etc.
Kuphatikiza apo, adsorbent yopangidwa kuchokera ku Cyclodextrin itha kugwiritsidwa ntchito popanga chromatographic adsorption.
Ntchito
1. α-Cyclodextrin Wonjezerani kukhazikika kwa zinthu: Pewani kusinthasintha, kuteteza kutsika;Anti-oxidation;Pewani kuwonongeka kwa optothermal;Anti-chemical kuwonongeka;Wonjezerani nthawi ya kutsimikizika kwa zinthuzo.
2. α-Cyclodextrin Wonjezerani kusungunuka kwa zinthu ndi bioavailability.
3. α-Cyclodextrin kupyolera mu mapangidwe a inclusion complex kuti akwaniritse fungo losangalatsa la chivundikiro.
4. α-Cyclodextrin Mankhwala osokoneza bongo kukhala olimba.
5. α-Cyclodextrin Kuteteza mankhwala - mankhwala, mankhwala - kugwirizana pakati pa zowonjezera.
6. α-Cyclodextrin Chepetsani zotsatirapo.
Kugwiritsa ntchito
1. α-Cyclodextrin imagwiritsidwa ntchito kuonjezera kukhazikika kwa zinthu: Pewani kuphulika, kuteteza kutsika;Anti-oxidation;
2. α-Cyclodextrin imagwiritsidwa ntchito poletsa kuwonongeka kwa optothermal;Anti-chemical kuwonongeka;Wonjezerani nthawi ya kutsimikizika kwa zinthuzo.
3. α-Cyclodextrin imagwiritsidwa ntchito kuonjezera kusungunuka kwa zinthu ndi bioavailability.
4. Kudzera mapangidwe kuphatikizika zovuta kukwaniritsa ogwira chivundikiro fungo losangalatsa.Mankhwala amadzimadzi kukhala olimba.
5. α-Cyclodextrin imagwiritsidwa ntchito poletsa mankhwala - mankhwala, mankhwala - kugwirizana pakati pa zowonjezera.
6. α-Cyclodextrin imagwiritsidwa ntchito kuchepetsa zotsatirapo.
Zamankhwala:
1. Kuchulukitsa kusungunuka kwa kupezeka kwachilengedwe
2. Kupititsa patsogolo bioavailability
3. Kusintha kapena kuwongolera kumasulidwa
4. Kuchepetsa kawopsedwe
5. Kupititsa patsogolo kukhazikika
Zodzikongoletsera:
1. Kuti zigwirizane ndi encapsulation ya zinthu zosakhazikika.
2. Kuonjezera alumali moyo wa zokometsera zodula.
Chakudya:
1.Kuletsa kutuluka kwa zinthu zosakhazikika.
2.Kuchotsa fungo loyipa.
3.Kuwonjezera kwambiri zotsatira za emulsification
α-Cyclodextrin imapezeka kuti ipange zovuta zolimba ndi mafuta a zakudya.Izi zimachepetsa bioavailability ndi kuyamwa kwamafuta.Amadziwika kuti amawongolera kuchuluka kwa triglyceride ndi leptin mu seramu.M'mitundu ya makoswe, α-Cyclodextrin ikuwonetsedwa kuti ipangitse chidwi cha insulin komanso kutulutsa mafuta m'chimbudzi.Chifukwa chake, α-Cyclodextrin imawonedwa kuti ndi yothandiza pochiza kunenepa kwambiri komanso matenda a metabolic.
Kuphatikizidwa mu FDA Inactive Ingredients Database: α-Cyclodextrin (makonzedwe a jekeseni);β-Cyclodextrin (mapiritsi apakamwa, gel osakaniza);γ-Cyclodextrin (IV jakisoni).M'gulu la Canada List of Acceptable Non-medicinal Ingredients (stabilizing agent; solubilizing agent);komanso mu mankhwala opangidwa ndi oral and rectal pharmaceutical ovomerezeka ku Europe, Japan, ndi USA.