Dantrolene Sodium Salt Hydrate CAS 14663-23-1 API Factory High Quality
Perekani ndi Kuyera Kwambiri ndi Ubwino Wokhazikika
Dzina la Chemical: Dantrolene Sodium Salt Hydrate
CAS: 14663-23-1
Chigoba Muscle Relaxant.Calcium Channel Inhibitor
API High Quality, Commercial Production
| Dzina la Chemical | Dantrolene Sodium Salt Hydrate |
| Mawu ofanana ndi mawu | 1- [5-(4-Nitrophenyl)furfurylideneamino]hydantoin Sodium Salt Hydrate |
| Nambala ya CAS | 14663-23-1 |
| Nambala ya CAT | RF-API78 |
| Stock Status | Mu Stock, Kupanga Kufikira Mazana a Kilogram |
| Molecular Formula | C14H11N4NaO5 |
| Kulemera kwa Maselo | 338.25 |
| Kusungunuka | Zosungunuka mu DMSO |
| Mkhalidwe Wotumiza | Kutumizidwa Pansi pa Kutentha Kozungulira |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Wachikasu-Orenji kupita ku Orange Crystalline.Palibe umboni wowoneka wa kuipitsidwa ndi zinthu zakunja |
| Chizindikiro A | Kulowetsedwa kwa IR (197K) |
| Chizindikiro B | Nthawi yosungira pachimake chachikulu mu chromatogram yokonzekera kuyesa imafanana ndi yomwe ili mu chromatogram ya kukonzekera kokhazikika, monga momwe zapezedwa poyesa. |
| Chizindikiro C | Imakwaniritsa zofunikira pakuyesa kwamoto kwa Sodium (191) |
| Chizindikiritso D | Gawo 1: Mpweya wowala, woyera, wa crystalline umapangidwa Gawo 2: Madziwo samasowa Gawo 3: Madziwo amasungunuka kwathunthu Gawo 4: Palibe mpweya wopangidwa |
| Mkati mwa Madzi (wolemba KF) | 14.5% ~ 17.0% |
| Tinthu Kukula | 90% zosakwana 200um |
| Kuyesa | 90.0% ~ 96.0% ya C14H10N405 pa anhydrous basis |
| Zogwirizana nazo | (HPLC, Area%) |
| Related Compound A | ≤0.15% |
| Kuphatikizana B | ≤0.50% |
| Zogwirizana ndi C | ≤0.30% |
| Zosungunulira Zotsalira | |
| Ethanol | ≤2000ppm |
| Methanol | ≤2000ppm |
| Acetone | ≤2000ppm |
| DMF | ≤620ppm |
| Zitsulo Zolemera | ≤10ppm |
| Shelf Life | zaka 2 |
| Test Standard | United States Pharmacopoeia (USP) |
| Kugwiritsa ntchito | Chigoba Muscle Relaxant.Calcium Channel Inhibitor |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
Dantrolene Sodium Salt Hydrate (CAS 14663-23-1), ndi molecule yaying'ono inhibitor ya Ryanodine receptor antagonist ndi Calcium channel inhibitor.Dantrolene Sodium Salt ndi chigoba chotsitsimula minofu, chomwe chimalepheretsa kutulutsa kwa Ca 2 + kuchokera ku sarcoplasmic reticulum.Kutsekeka kwa Ca2 + kumasulidwa kuchokera ku sarcoendoplasmic reticulum, yokhudzana kwambiri ndi chisangalalo ndi kutsika kwa minofu, kumapanga mphamvu yotsitsimula minofu yogwirizana ndi Dantrolene.Neurotoxicity yomwe imawonetsedwa ndi kutchulidwa kwa glutamate imalumikizidwa ndi kukwera kwambiri kwa cytoplasmic Ca2+ milingo, ndipo Dantrolene amawonetsedwa ngati neuroprotective agent motsutsana ndi neurotrasmitter-induced excitotoxicity.Dantrolene, Sodium Salt ndi inhibitor ya RyR-1 ndi RyR-3.
