DAPT (GSI-IX) CAS 208255-80-5 γ-Secretase Inhibitor Assay >98.0% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. ndiye wopanga wamkulu wa DAPT (GSI-IX) (CAS: 208255-80-5) wokhala ndi mawonekedwe apamwamba, γ-Secretase Inhibitor.Ruifu Chemical imapereka ma amino acid angapo ndi zotumphukira.Titha kupereka zoperekera padziko lonse lapansi, zochepa komanso zochulukirapo zomwe zilipo.Gulani DAPT,Please contact: alvin@ruifuchem.com
| Dzina la Chemical | DAPT |
| Mawu ofanana ndi mawu | GSI-IX;γ-Secretase Inhibitor IX;gamma-Secretase Inhibitor;LY-374973;(3,5-Difluorophenylacetyl)-Ala-Phg-OtBu;(3,5-Difluorophenylacetyl) -L-Alanyl-L-2-Phenylglycine tert-Butyl Ester;N- [N-(3,5-Difluorophenacetyl)-L-Alanyl]-S-Phenylglycine t-Butyl Ester;(2S)-N-[2-(3,5-Difluorophenyl)acetyl]-L-Alanyl-2-Phenyl-glycine 1,1-Dimethylethyl Ester |
| Stock Status | Zilipo |
| Nambala ya CAS | 208255-80-5 |
| Molecular Formula | Chithunzi cha C23H26F2N2O4 |
| Kulemera kwa Maselo | 432.47 |
| Kuchulukana | 1.213 g/cm3 |
| Melting Point | 142.0 ~ 146.0 ℃ |
| Zomverera | Kutentha Kwambiri |
| Kusungunuka | Zosungunuka mu DMSO |
| Kusungirako Temp. | Sungani pa 2-8 ℃ |
| COA & MSDS | Likupezeka |
| Mtundu | Ruifu Chemical |
| Ndemanga za Chitetezo | 24/25 - Pewani kukhudzana ndi khungu ndi maso. | ||
| WGK Germany | 3 | HS kodi | 2922491990 |
| Zinthu | Miyezo Yoyendera | Zotsatira |
| Maonekedwe | Ufa Woyera kapena Woyera wa Crystalline | Zimagwirizana |
| Kutaya pa Kuyanika | <0.40% | 0.21% |
| Zotsalira pa Ignition | <0.40% | 0.20% |
| Zitsulo Zolemera (monga Pb) | ≤20ppm | <20ppm |
| Njira Yoyesera / Kusanthula | >98.0% (HPLC) | 98.62% |
| Carbon ndi Elemental Analysis | 62.1-64.1% | Zimagwirizana |
| Nayitrogeni ndi Elemental Analysis | 6.20-6.70% | Zimagwirizana |
| Infrared Spectrum | Zimagwirizana ndi Kapangidwe | Zimagwirizana |
| Chithunzi cha NMR | Zimagwirizana ndi Kapangidwe | Zimagwirizana |
| Mapeto | Chogulitsachi mwa Inspection Accords ndi Enterprise Standard | |
| Shelf Life | Miyezi 24 Kuchokera Tsiku Lopanga Ngati Zasungidwa Moyenera | |
Phukusi: Botolo la Fluorinated, thumba la Aluminiyamu zojambulazo, 25kg / Cardboard Drum, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Sungani m'mitsuko yomata pamalo ozizira, owuma (sitolo pa 2-8 ℃) ndi nyumba yosungiramo mpweya wabwino kutali ndi zinthu zosagwirizana.Tetezani ku kuwala ndi chinyezi.
Kodi kugula?Chonde lemberaniDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
DAPT (GSI-IX) (CAS: 208255-80-5), inhibitor yamphamvu komanso yeniyeni ya γ-secretase.DAPT ndi inhibitor ya γ-secretase (IC50 mu neuroprimary neurons = 115 nM ya Aβ yonse kapena 200 nM ya Aβ42 makamaka).Kuwongolera pakamwa kwa DAPT kwawonetsedwa kuti kumachepetsa milingo ya Aβ muubongo, cerebrospinal fluid ndi plasma kuchokera ku mbewa ndi makoswe.DAPT imatchinga ma Notch signing omwe amalimbikitsa kusiyanitsa kwa ma neuronal a ma cell oyambira.Imakulitsa ma cell a iPS opanda oncogenes KLF4 ndi CMYC5.Cell permeable.DAPT imagwiritsidwa ntchito pofufuza mapangidwe a β-amyloid.DAPT yasonyezedwa kuti imalepheretsa chizindikiro cha Notch mu maphunziro a autoimmune ndi lymphoproliferative matenda, monga ALPS ndi lupus erythematosus, komanso kukula kwa maselo a khansa, angiogenesis, ndi kusiyanitsa kwa maselo amtundu wa pluripotent.Imalepheretsa kusaina kwa Notch mu vitro.Imalepheretsa kupanga kwa Aβ ndi Aβ42 mu zikhalidwe zoyambirira zaumunthu (makhalidwe a IC50 ndi 115 ndi 200 nM, motsatira) popanda zotsatira pa APPα ndi APPβ.Magazi-ubongo chotchinga permeable.3D Growth matrix gawo ndi gawo la cerebral organoid differentiation media.
