DCC CAS 538-75-0 Dicyclohexylcarbodiimide Purity>99.0% (GC) Peptide Coupling Reagent Factory
Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga N,N'-Dicyclohexylcarbodiimide (DCC) (CAS: 538-75-0) yokhala ndipamwamba kwambiri.Ruifu Chemical imapereka ma reagents oteteza ndi ma reagents ophatikiza.Ruifu atha kubweretsa padziko lonse lapansi, mtengo wampikisano, zochepa komanso zochulukirapo zomwe zilipo.Gulani DCC,Please contact: alvin@ruifuchem.com
Dzina la Chemical | N, N'-Dicyclohexylcarbodiimide |
Mawu ofanana ndi mawu | DCC;Dicyclohexylcarbodiimide |
Nambala ya CAS | 538-75-0 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | Chithunzi cha C13H22N2 |
Kulemera kwa Maselo | 206.33 |
Melting Point | 32.0 ~ 36.0 ℃ |
Boiling Point | 122.0 ~ 124.0℃/6 mm Hg(lit.) |
Kuchulukana | 1.247 g/mL pa 25 ℃ |
Zomverera | Sichinyezimira |
Kusungunuka mu Madzi | Zosasungunuka m'madzi |
Kusungunuka | Zosungunuka mu Methanol |
Kusungirako Temp. | Malo Ozizira & Owuma (2~8℃) |
COA & MSDS | Likupezeka |
Gulu | Coupling Reagents |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | White Crystal kapena Light Yellow Liquid |
Kuyera / Kusanthula Njira | >99.0% (GC) |
Melting Point | 32.0℃~36.0℃ |
Kutaya pa Kuyanika | <0.50% |
Mayeso Oyankhira (Mu Acetone) | Zomveka & Zowonekera |
Zinthu Zosasungunuka mu Acetone | Palibe |
Zonse Zonyansa | <1.00% |
Kusungirako | Tetezani kuwala ndikusunga pamalo ozizira komanso owuma |
Test Standard | Enterprise Standard |
Kugwiritsa ntchito | Peptide Coupling Reagents |
Phukusi:Botolo, 25kg / Drum, kapena malinga ndi zomwe kasitomala amafuna.
Mkhalidwe Wosungira:Chinyezi Chosamva, sungani kutali ndi madzi/chinyontho.Sungani m'mitsuko yomata pamalo ozizira komanso owuma (2~8 ℃) kutali ndi zinthu zomwe sizingagwirizane.
Manyamulidwe:Kutumiza kudziko lonse lapansi ndi FedEx / DHL Express.Perekani mwamsanga ndi yodalirika yobereka.
1 Cholinga
Fotokozani ndondomeko yoyendera ya DCC.
2 Mtundu
Imagwira ntchito pakuwunika kwa DCC mu kampani ya Ruifu.
3 Maziko
Chinese Pharmacopoeia 2005 kope, ogwira ntchito mkati ulamuliro muyezo.
4. Udindo
4.1 Dipatimenti Yoyang'anira Ubwino ili ndi udindo wophunzitsa ndi kuwongolera.
4.2 Wofufuzayo adzakhala ndi udindo pa ntchito yeniyeni komanso kulondola kwa zotsatira za mayeso.
5 Njira Zogwirira Ntchito
5.1 Katundu: Izi ndi zoyera zamadzimadzi kapena zachikasu zopepuka.
Tengani nyemba zokwana magalamu 100 ndikuziyika mu beaker, kuziziziritsa mpaka kuzizira kwambiri, ndiyeno zitenthetseni kuti zisungunuke.Yang'anani mtundu ndi kristalo mosiyana
5.2 Kuzizira kozizira
Ikani chitsanzo cha 15ml mu chubu choyesera cha 20ml.Chitsanzocho chinasungunuka kwathunthu chikatenthedwa pa 45 ℃.Tumizani chubu choyesera mubafa lamadzi pa 25 ℃
Kenaka, gwedezani ndikuyika chisindikizo cha thermometer.Masekondi 30 aliwonse mpaka madziwo atakhazikika, ndiye masekondi 15 aliwonse,
Kutentha komwe kukuwonetsedwa ndikuzizira mpaka thermometer ikhalabe yosasinthika kwa pafupifupi 1min.
5.3 Kutsimikiza kwa zomwe zili
Kutsimikiza ndi chromatography ya gasi (Zowonjezera za Chinese Pharmacopoeia Edition 2005).
Chida: Kexiao GC1690 gawo la mpweya wa Chromatograph: ATSE-54
Kutentha kwapakati: 230 ℃ mpweya wonyamula: nayitrogeni
Kuzindikira kutentha: 300 ℃ jekeseni kutentha: 280 ℃
Chiŵerengero cha Shunt: 50: 1 Detector: FID
Lowetsani 0.2ul ya njira yoyesera mu chromatograph kwa mphindi 15.Kuyesedwa ndi dera normalization njira.
5.4 Zotsatira
Kuwerengedwa ndi njira yokhazikika ya dera, DCC sikhala pansi pa 99.0%.
Zizindikiro Zowopsa
R23/24/25 - Poizoni pokoka mpweya, kukhudzana ndi khungu komanso kumeza.
R34 - Imayambitsa kuyaka
R40 - Umboni wochepa wa zotsatira za carcinogenic
R43 - Itha kuyambitsa chidwi pakukhudzana ndi khungu
R41 - Kuopsa kwa kuwonongeka kwakukulu kwa maso
R36/38 - Kukwiyitsa maso ndi khungu.
R21 - Zowopsa pokhudzana ndi khungu
R24 - Pokhudzana ndi khungu
R22 - Zowopsa ngati zitamezedwa
R62 - Chiwopsezo chotheka cha kulephera kubereka
R37/38 - Kukwiyitsa dongosolo la kupuma ndi khungu.
R10 - Yoyaka
R61 - Zitha kuvulaza mwana wosabadwa
R26 - Ndiwowopsa kwambiri pokoka mpweya
R38 - Zowawa pakhungu
R20/22 - Zowopsa pokoka mpweya komanso ngati zitamezedwa.
Kufotokozera Zachitetezo
S26 - Mukakhudzana ndi maso, muzimutsuka nthawi yomweyo ndi madzi ambiri ndipo funsani malangizo achipatala.
S36/37/39 - Valani zovala zodzitchinjiriza zoyenera, magolovesi ndi chitetezo chamaso/nkhope.
S45 - Pakachitika ngozi kapena ngati simukumva bwino, funsani upangiri wachipatala nthawi yomweyo (onetsani chizindikirocho ngati kuli kotheka.)
S41 - Pakakhala moto ndi / kapena kuphulika musapume utsi.
S24 - Pewani kukhudzana ndi khungu.
S37/39 - Valani magolovesi oyenera komanso chitetezo chamaso / kumaso
S24/25 - Pewani kukhudzana ndi khungu ndi maso.
S36 - Valani zovala zoyenera zodzitetezera.
S16 - Khalani kutali ndi magwero oyatsira.
S53 - Pewani kuwonekera - pezani malangizo apadera musanagwiritse ntchito.
S28 - Mukakhudza khungu, sambani nthawi yomweyo ndi sopo wambiri.
Ma ID a UN 2922 8/PG 2
WGK Germany 3
Mtengo wa RTECS FF2160000
FLUKA BRAND F MAKODI 3-8-10-21
TSCA Inde
HS kodi 2925290090
Kalasi Yowopsa 6.1
Packing Gulu II
Poizoni LD50 pakamwa pa Kalulu: 1110 mg/kg LD50 dermal Rat 71 mg/kg
DCC (N,N'-Dicyclohexylcarbodiimide, CAS: 538-75-0) imagwiritsidwa ntchito mu chemistry ya peptide ngati cholumikizira cholumikizira.Makamaka ntchito yokumba synthesis wa peptides Condensation wa amino zidulo.Mwachitsanzo, mu Fmoc-solid phase synthesis, gulu la carboxyl la amino acid limapanga mgwirizano wa amide ndi gulu la amino la amino acid ina.Kuti gulu la carboxyl likhale lomvera kuukira kwa ma nucleophiles, atomu ya okosijeni yomwe ili ndi mpweya woipa imayenera kulowetsedwa kukhala gulu lochoka bwino, ndipo DCC imagwira ntchitoyi.Atomu ya okosijeni ya gulu la carboxyl pa amino acid imakhala ngati nucleophile kuukira atomu ya kaboni pakati pa molekyulu ya DCC kuti DCC imalumikizana ndi gulu la carboxyl kupanga mawonekedwe a ester, kupanga nucleophilic attack ya gulu la amino. zosavuta kuchita coupling reagent.
DCC imagwiritsidwa ntchito popanga komanso kutaya madzi m'thupi kwa amikacin ndi amino acid.ndi yabwino yotsika kutentha kwa biochemical dehydrating agent ndipo imagwiritsidwanso ntchito popanga ma acid, anhydrides, aldehydes, ketoni, ndi zina zotero. Ku Japan, mankhwala osokoneza bongo omwe amagwiritsidwa ntchito pa glutathione chifukwa cha 90% ya ntchito yonse.Mankhwalawa akagwiritsidwa ntchito ngati dehydration ndi condensing agent, amatha kuchitapo kanthu pakanthawi kochepa kutentha kwa firiji, ndipo mankhwalawa atatha kuchitapo kanthu ndi dicyclohexylurea.Popeza solubility wa mankhwala mu zosungunulira organic ndi laling'ono kwambiri, zimene mankhwala n'zosavuta kupatukana;nthawi yomweyo, chifukwa mankhwalawa ndi ovuta kusungunuka m'madzi, zomwe zimachitika zimatha kupitilira ngakhale munjira yamadzi.Mankhwalawa amagwiritsidwanso ntchito popanga peptides ndi nucleic acid.Kugwiritsa ntchito mankhwalawa kumatha kuphatikizira ma peptides kuchokera kumagulu okhala ndi magulu aulere a carboxyl ndikuphatikizana ndi magulu a amino aulere pa kutentha kwa firiji, ndipo zokolola zake ndizambiri.Ntchito kupanga hypertensives ndi cyclic adenosine monophosphate.amagwiritsidwa ntchito ngati biochemical reagent ndi organic synthesis dehydration condensing agent.