Decitabine CAS 2353-33-5 Purity> 99.5% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. ndiye wopanga komanso wogulitsa Decitabine (CAS: 2353-33-5) wokhala ndipamwamba kwambiri.Titha kupereka COA, kutumiza padziko lonse lapansi, zochepa komanso zochulukirapo zomwe zilipo.Ngati muli ndi chidwi ndi mankhwalawa, chonde tumizani zambiri zatsatanetsatane zikuphatikiza nambala ya CAS, dzina lazinthu, kuchuluka kwa ife.Please contact: alvin@ruifuchem.com
| Dzina la Chemical | Decitabine |
| Mawu ofanana ndi mawu | 5-Aza-2'-Deoxycytidine;5-Aza-1-(2-Deoxy-β-D-Ribofuranosyl)cytosine;5-Aza-CdR;5-Aza-dC;5-Deoxy-2'-Azacytidine;ZdCyd;DAC;β-Decitabine |
| Nambala ya CAS | 2353-33-5 |
| Nambala ya CAT | Mtengo wa RF2728 |
| Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
| Molecular Formula | C8H12N4O4 |
| Kulemera kwa Maselo | 228.21 |
| Melting Point | 191 ℃ (Dec.) |
| Zomverera | Simamva Kutentha, Kutentha |
| Kusungunuka | Kusungunuka mu DMSO;Zosungunuka pang'ono m'madzi |
| Mtundu | Ruifu Chemical |
| Kanthu | Zofotokozera |
| Maonekedwe | Ufa Woyera kapena Woyera wa Crystalline |
| Chizindikiro A | IR: Zitsanzo za IR Spectrum Zimagwirizana ndi za Standard |
| Chizindikiro B | HPLC: RT ya Major Peak of the Test Solution Imagwirizana ndi Standard Solution |
| Chizindikiro C | PXRD: Zabwino |
| Kuyera / Kusanthula Njira | > 99.5% (HPLC) |
| Alpha | +56.0°~ 63.0° |
| Kutaya pa Kuyanika | <0.50% |
| Zotsalira pa Ignition | <0.10% |
| Zitsulo Zolemera | <20ppm |
| Zogwirizana nazo | |
| α-Decitabine | <0.20% |
| Chidetso Chosadziwika Chokha | <0.20% |
| Zonse Zonyansa | <0.50% |
| Zosungunulira Zotsalira | |
| DMSO | <0.50% |
| Methanol | <0.30% |
| Methyl Formate | <0.05% |
| Acetonitrile | <0.041% |
| Kusungunuka | Colorless Clear 50 mg/ml, HOAc ndi H2O (1:1) Pass |
| Test Standard | Enterprise Standard |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, 25kg/Cardboard Drum, kapena malinga ndi lamulo la kasitomala
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala ndi chinyezi
Kodi kugula?Please contact: sales@ruifuchem.com or alvin@ruifuchem.com
Zaka 15 Zokumana nazo?Tili ndi zaka zopitilira 15 pakupanga ndi kutumiza kunja kwamitundu yambiri yamankhwala apamwamba kwambiri kapena mankhwala abwino.
Misika Yaikulu?Gulitsani kumsika wapakhomo, North America, Europe, India, Russia, Korea, Japan, Australia, etc.
Ubwino wake?Ubwino wapamwamba, mtengo wotsika mtengo, ntchito zamaluso ndi chithandizo chaukadaulo, kutumiza mwachangu.
UbwinoChitsimikizo?Njira yoyendetsera bwino kwambiri.Zida zaukadaulo zowunikira zikuphatikizapo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Zitsanzo?Zogulitsa zambiri zimapereka zitsanzo zaulere zowunikira zabwino, mtengo wotumizira uyenera kulipidwa ndi makasitomala.
Factory Audit?Takulandilani ku fakitale.Chonde panganitu nthawi yokumana.
MOQ?Palibe MOQ.Dongosolo laling'ono ndilovomerezeka.
Nthawi yoperekera? Ngati mkati mwa katundu, kubweretsa masiku atatu kutsimikizika.
Mayendedwe?Ndi Express (FedEx, DHL), ndi Air, ndi Nyanja.
Zolemba?Pambuyo pa ntchito yogulitsa: COA, MOA, ROS, MSDS, ndi zina zotero.
Custom Synthesis?Itha kukupatsirani ntchito zophatikizira zomwe zikugwirizana bwino ndi zosowa zanu zofufuza.
Malipiro Terms?Invoice ya Proforma idzatumizidwa kaye mukatsimikizira kuyitanitsa, ndikuyika zambiri zathu zakubanki.Malipiro a T/T (Telex Transfer), PayPal, Western Union, etc.
Decitabine (CAS: 2353-33-5) (dzina la malonda Dacogen), kapena 5-Aza-2'-Deoxycytidine.Mankhwala, ndi analogue ya cytidine.Decitabine ndi wothandizira wa hypomethylating.Decitabine yakhazikitsidwa pochiza matenda a myelodysplastic syndromes (MDS).MDS ndi gulu la matenda a hematologic omwe amakhudza mafupa omwe amachititsa kuti maselo a magazi asapangidwe bwino.Kuphatikiza apo, odwala omwe ali ndi MDS ali pachiwopsezo chachikulu chopita ku acute myeloid leukemia (AML).Thandizo lachikhalidwe limaphatikizapo kuikidwa magazi, kukula kwa hematopoietic, ndi mankhwala oletsa tizilombo toyambitsa matenda, koma njirazi zimangowonjezera moyo wabwino ndi zotsatira zokayikitsa pakusintha kwa matenda.Ngakhale kupatsirana kwa stem cell ndi njira yaukali, yokhoza kuchiritsa, ukalamba kapena zovuta zina zathanzi za odwala ambiri zimawalepheretsa kuganizira izi.Kupita patsogolo kwaposachedwa kwa etiology ya MDS, komabe, kwachititsa kuti pakhale gulu latsopano la mankhwala omwe amadziwika kuti '' demethylating agents ''.Decitabine ikutsatira kukhazikitsidwa kwabwino kwa DNA methyltransferase inhibitor Azacitidine.Imasokoneza DNA poletsa DNA methyltransferase.Zimagwira ntchito mofanana ndi Azacitidine, ngakhale kuti decitabine ikhoza kuphatikizidwa muzitsulo za DNA pamene azacitidine ikhoza kuphatikizidwa mu unyolo wa DNA ndi RNA.Zopangira kafukufuku: Decitabine imagwiritsidwa ntchito kwambiri mu biology ya maselo, pharmacology, ndi kafukufuku wina wasayansi.Decitabine monga DNA methyltransferase inhibitor, njira yosinthika ya DNA methylation, inachititsa maselo a chotupa ku maselo abwinobwino kuti asiyanitse kapena kuyambitsa chotupa cell apoptosis.Chonde dziwani kuti kuchuluka kwa Decitabine kumatha kuchita nawo cytotoxic: kumatha kulepheretsa kaphatikizidwe ka DNA kaphatikizidwe ka cell kufa.
