Doxorubicin Hydrochloride CAS 25316-40-9 API USP Standard Factory High Purity
Wopanga ndi Kuyera Kwambiri ndi Ubwino Wokhazikika
Dzina la Mankhwala: Doxorubicin Hydrochloride
CAS: 25316-40-9
Antitumor Antibiotic wothandizira.Imalepheretsa DNA Topoisomerase II
API High Quality, Commercial Production
Dzina la Chemical | Doxorubicin Hydrochloride |
Mawu ofanana ndi mawu | Doxorubicin HCl;Adriamycin HCL;Hydroxydaunorubicin Hydrochloride |
Nambala ya CAS | 25316-40-9 |
Nambala ya CAT | RF-API38 |
Stock Status | Mu Stock, Kupanga Kukula Mpaka Matani |
Molecular Formula | C27H30ClNO11 |
Kulemera kwa Maselo | 579.98 |
Mtundu | Ruifu Chemical |
Kanthu | Zofotokozera |
Maonekedwe | Ufa Wofiira-Wofiira kapena Wakristalo Wofiira;Palibe umboni wowoneka wa kuipitsidwa ndi zinthu zakunja |
Kusungunuka | Zosungunuka m'madzi ndi methanol;kusungunuka pang'ono mu ethanol;pafupifupi osasungunuka mu acetone |
Chizindikiro A | Mawonekedwe a IR amafanana ndi mawonekedwe a IR a muyezo wanthawi zonse |
Chizindikiro B | Nthawi yosungirako pachimake cha doxorubicin mu chromatogram ya Kukonzekera kwa Assay ikufanana ndi yomwe ili mu chromatogram ya Kukonzekera kwa Standard, monga momwe anapezera mu Assay. |
pH | 4.0-5.5 |
Mkati mwa Madzi | ≤4.0% |
Zogwirizana nazo | |
Chidebe A (Doxorubicinol) | ≤0.50% |
Chidetso China Chilichonse Chosadziwika | ≤0.20% |
Zonyansa Zonse Zosadziwika | ≤0.50% |
Zonse Zonyansa | ≤1.0% |
Kuyesa | 98.0% ~ 102.0% ya C27H30ClNO11 yowerengedwa pa maziko a anhydrous, opanda zosungunulira |
Zosungunulira Zotsalira | |
Acetone | ≤0.50% |
Acetone + Ethanol | ≤2.5% |
Methanol | ≤0.30% |
Dichloromethane | ≤0.06% |
Test Standard | United States Pharmacopeia (USP) Reference Standard |
Kugwiritsa ntchito | Active Pharmaceutical Ingredient (API) |
Phukusi: Botolo, Aluminiyamu zojambulazo thumba, makatoni ng'oma, 25kg / Drum, kapena malinga ndi zofuna za kasitomala.
Mkhalidwe Wosungira:Sungani muzitsulo zosindikizidwa pamalo ozizira ndi owuma;Tetezani ku kuwala, chinyezi ndi tizilombo towononga.
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Shanghai Ruifu Chemical Co., Ltd. ndi omwe amapanga komanso ogulitsa Doxorubicin Hydrochloride (CAS: 25316-40-9) yokhala ndipamwamba kwambiri.Doxorubicin hydrochloride, mankhwala a cytotoxic anthracycline, ndi anti-cancer chemotherapy agent.Doxorubicin hydrochloride ndi DNA yamunthu yamphamvu topoisomerase I ndi topoisomerase II inhibitor yokhala ndi IC50s ya 0.8 μM ndi 2.67 μM, motsatana.Doxorubicin hydrochloride imapangitsa apoptosis ndi autophagy.Doxorubicin ndi mankhwala amphamvu a antitumor omwe amagwira ntchito motsutsana ndi matenda osiyanasiyana, kuphatikizapo khansa ya m'magazi, sarcoma, khansa ya m'mawere, khansa yaing'ono ya m'mapapo ndi khansa ya m'mawere.
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